circulating cell-free DNA
Prognostic and diagnostic value of eosinopenia, C reactive protein, procalcitonin, and circulating cell free DNA in critically ill patients admitted with suspicion of sepsis
... of circulating cell-free DNA (cf-DNA) concentrations, compared with C-reactive protein (CRP), procalcitonin (PCT) and eosinophil count, in the diagnosis of infections in patients with ...
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Circulating Cell-Free DNA in Dogs with Mammary Tumors: Short and Long Fragments and Integrity Index
... Circulating cell-free DNA (cfDNA) has been considered an interesting diagnostic/prognostic plasma biomarker in tumor-bearing ...lysed circulating cells, and some yet unrevealed ...
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Circulating cell-free DNA as a prognostic and predictive biomarker in non-small cell lung cancer
... Circulating cell-free DNA (cfDNA), which can be obtained from plasma or serum by non-invasive procedures, has showed great potential to predict treatment response and survival for cancer ...
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<p>Circulating Cell-Free DNA as Inflammatory Marker in Egyptian Psoriasis Patients</p>
... Circulating cell-free DNA appears following cell damage, and its levels are increased in pathological con- ditions characterized by marked in fl ammation such as cancer, severe sepsis, ...
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Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib
... in DNA iso- lated from plasma samples obtained on cycle 1 day 1 prior to treatment, cycle 1 day 8, and cycle 2 day ...before DNA pre- paration, with cell debris removed by ...of free ...
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Circulating cell free DNA based epigenetic assay can detect early breast cancer
... cfDNA: circulating cell-free DNA; CNA: copy number alteration; CPXM1: carboxypeptidase X (M14 family) member1; CREM: cAMP-responsive element modulator; CTC: circulating tumor ...
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Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer
... with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) emerging as “ liquid biopsies ” ...of circulating tumor DNA (ct-DNA) and CTCs ...
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KRAS mutations in blood circulating cell-free DNA: a pancreatic cancer case-control study
... plasma circulating cell-free DNA (cfDNA) samples as non-invasive biomarkers for the detection of pancreatic cancer has never been evaluated in a large case-control ...
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<p>The value of the plasma circulating cell-free DNA concentration and integrity index as a clinical tool for prostate cancer diagnosis: a prospective case–control cohort study in an Iranian population</p>
... of circulating cell-free DNA (ccfDNA) in plasma/serum as a liquid biopsy which could replace tissue biopsy and facilitate the evaluation of focal ...tumor DNA in cancerous patients. ...
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<p>Molecular Alterations in Circulating Cell-Free DNA in Patients with Colorectal Adenoma or Carcinoma</p>
... blood cell and plasma samples for each patient were processed for pairwise variant calling using VarScan ...blood cell samples; the P-value threshold to call a somatic site was ...blood cell samples ...
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Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition.
... Prostate cancer is a major cause of male cancer mortality globally. Studies indicate substantial inter- and intra-patient genomic heterogeneity although treatment to date has not incorporated molecular stratification. ...
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Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing
... plasma DNA was lost to follow-up. The median recurrence-free survival time for patients with tumor-associated somatic mutations detected in plasma DNA was 89 days (range, 34 to 299 days), compared ...
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DNA methylation analysis of selected genes for the detection of early-stage lung cancer using circulating cell-free DNA
... The DNA was extracted from 500 µL of plasma of the sub- jects using a QIAamp MinElute Virus Spin Kit (Qiagen, Hilden, Germany), according to the manufacturer’s in- ...extracted DNA was amplified using a ...
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Circulating cell-free DNA has a high degree of specificity to detect exon 19 deletions and the single-point substitution mutation L858R in non-small cell lung cancer
... “cell free DNA OR circulating DNA OR circulating tumor DNA OR serum DNA OR plasma DNA” AND “lung cancer OR non-small cell lung cancer” AND “EGFR OR ...
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Cancer gene mutation detection in circulating cell free DNA in blood
... (short DNA oligonucleotides complementary to a specific target DNA sequence) but they additionally have a fluorescent “reporter” dye molecule bound to the ...synthesised DNA molecule (during PCR) the ...
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<p>Circulating Cell-Free DNA or Circulating Tumor DNA in the Management of Ovarian and Endometrial Cancer</p>
... plasma DNA were detected (before che- motherapy and at relapse) in 138 patients with stage IC – IV OC who experienced a ...of DNA mismatch repair (MMR) might involve in the process of acquired drug ...
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Liquid Biopsy in Liquid Tumors
... need. Circulating cell free DNA (ccfDNA), other cir- culating nucleic acids such as microRNA and circulating tumor cells (CTCs), can be obtained from a peripheral blood ...of ...
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Emerging molecular technologies in renal cell carcinoma: liquid biopsy
... the circulating tumor cells (CTCs) and cell-free nucleic acids ...(i.e., circulating cell-free DNA (ccfDNA), circulating tumor DNA (ctDNA), ...
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Cell Free DNA and CD38 Expression on T helper Cells as Biomarkers of Disease Activity in Rheumatoid Arthritis
... life. Circulating cell-free DNA (cfDNA) is a cell damage marker, while CD38 molecule expressed on immune cells is involved in activation, and survival ...
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Next-generation sequencing-based genomic profiling analysis reveals novel mutations for clinical diagnosis in Chinese primary epithelial ovarian cancer patients
... clear cell carcinoma (OCCCs) ...samples, circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) [23] have emerged as “liquid biopsies” for non-invasive ...
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