circulating microRNAs
Circulating microRNAs as potential diagnostic biomarkers for osteoporosis
... 30 obtained from the microRNA PCR array were considered to be below the detection level of the reaction. Quantitation of microRNA levels using real-time quantitative PCR [RT-qPCR]. Real-time quan- titative PCR (RT-qPCR) ...
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Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease
... termed microRNAs, has been shown to be altered in ...Furthermore, microRNAs identified as being highly expressed in breast cancer tumours can also be detected in the ...circulation. Circulating ...
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Circulating microRNAs and prediction of asthma exacerbation in childhood asthma
... Additional file 1: Circulating MicroRNAs and Prediction of Asthma Exacerbation in Childhood Asthma. e-Table S1. Asthma Exacerbation Clinical Score. e-Table S2. Cross-validation (10-fold) of AUROC (all ...
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A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer
... [5]. MicroRNAs are involved in several, essential biological processes, and based on microRNA profiles, tumor cells can be distinguished from normal cells ...release microRNAs into circulation which can be ...
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Original Article Circulating microRNAs as potential biomarkers for unstable angina
... of circulating microRNAs (miRNAs) for differentiating UA from non-ischemic chest pain (NICP) in the ...of circulating miRNAs in patients with UA were evaluated relative to individuals with NICP ...
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Circulating microRNAs as Specific Biomarkers for Breast Cancer Detection
... Circulating microRNAs have drawn a great deal of devotion as hopeful and novel biomarkers for the breast ...tumor. microRNAs (miRNAs) are the main class of small, noncoding RNA molecules that control ...
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Circulating microRNAs predict survival of patients with tumors of glial origin
... Only miR-4443 and miR-549a were signi fi cantly differentiating be- tween Glial Tumors and CTRL at both RT-qPCR and NanoString. ISH staining showed stronger differences of miR-4443 expression in glial tu- mors compared to ...
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Circulating microRNAs are deregulated in overweight/obese children: preliminary results of the I.Family study
... mainly prompted by the massive recruitment of macro- phages into adipose tissues [11]. Adipogenesis is tightly controlled by a mixture regulatory signals including endo- cellular transcription factors and ...
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Profiling of circulating microRNAs in children with recent onset of type 1 diabetes
... particular, circulating miRNA patterns are cur- rently being investigated as potential biomarkers for metabolic diseases and cancers as a means of providing noninvasive, rapid, sensitive, and specific diagnostic ...
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Novel circulating microRNAs expression profile in colon cancer: a pilot study
... opment of a positive and effective preventive measure is a major public health concern [1]. Additionally, early diagnosis of cancer in the clinical setting is particularly important [2]. As a new detection technology, ...
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Circulating microRNAs as biomarkers for diffuse myocardial fibrosis in patients with hypertrophic cardiomyopathy
... between circulating miRNAs and regional fibro- sis quantified by LGE in HCM patients, and they found that miR-29a significantly correlated with regional fibro- sis ...
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Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer
... MicroRNAs (miRNAs), a large family of small (20–22 nucleotides) non-coding RNAs, regulate approximately 30% of the genes in the human genome at the post-transcriptional level, by binding to the complemen- tary ...
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Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs
... Figure 1. Dendritic cells are the recipients of circulating miR-410-5p produced by cancer cells. A. Levels of miR-410-5p in serum from RM-1 tumor-bearing mice that were subcutaneously injected with ...
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Circulating microRNAs are associated with early childhood obesity: results of the I.Family Study
... Although numerous aspects remain to be clarified, miR- NAs research has contributed to shed lights on epigen- etic mechanisms related to obesity. Circulating miRNAs are increasingly explored as innovative and ...
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Association of circulating microRNAs with prevalent and incident knee osteoarthritis in women: the OFELY study
... purpose, microRNAs (miRNAs) are new potential ...their circulating level in patients might reflect the underlying disease state ...Indeed, circulating miR- NAs are considered to be attractive ...
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<p>Circulating microRNAs as promising diagnostic biomarkers for pancreatic cancer: a systematic review</p>
... on microRNAs (miRNAs) has become a popular research fi eld for the early diagnosis of ...malignancies. MicroRNAs are highly conserved, small noncoding RNA species of 17 – 25 nucleotides in length 14 and ...
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Circulating microRNAs correlate to clinical parameters in individuals with allergic and non-allergic asthma
... Our study shows that several miRNAs found in the serum correlate to clinically relevant parameters and are significantly and differentially expressed not only be- tween healthy individuals and asthmatics, but also be- ...
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Circulating microRNAs as potential biomarkers to detect transformation of Barrett’s oesophagus to oesophageal adenocarcinoma
... seven circulating miRNAs (miR-128-3 p, miR-328-3 p, miR-143-3 p, miR-144-3 p, miR-15a-5p, miR-1-3 p and miR-133b), consisting of three different characteristic miRNA groups, were identified as prom- ising ...
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Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO)
... impact of dysregulation of a single miRNA can be consid- erable. Recent research has shown that miRNAs have potential as non-invasive biomarkers for the diagnosis and prognosis of disease as well as monitoring of ...
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Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failure
... dyspnea, circulating miR-423-5p has been identified as a potential biomarker that can distinguish patients with left-sided heart failure from those with other causes of dyspnea ...of circulating miRNAs in ...
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