claudin-5
Dysregulated claudin 5 cycling in the inner retina causes retinal pigment epithelial cell atrophy
... of claudin-5 at the iBRB in the aging eye, ongoing studies aimed at elucidating changes in retinal permeability in preclinical species and AMD patients will extend our ...
14
Original Article Roles of claudin-5 and von Willebrand factor in patients with rheumatoid arthritis
... used. Claudin-5 and vWF assess- ment were derived from serum samples gath- ered from the patients known to have RF and anti-CCP titers in the normal ...
6
The Role of Claudin-5 on Xenopus Heart Development
... 2005). Compare with other factors such as noggin, chd can gain detectable dorsalizing and neutralizing activity in lower amount and has much stronger blocking function for BMP4 (Piccolo, 1996). Except for dorsal axis ...
87
Original Article Hydrogen-rich saline prevents the down regulation of claudin-5 protein in septic rat lung via the PI3K/Akt signaling pathway
... the severity of pulmonary edema, were incre- ased in LPS group as compared with that in control group. As reported in previous studies [17], the intraperitoneal injection of hydrogen- rich saline improved lung function ...
11
Dose dependent expression of claudin 5 is a modifying factor in schizophrenia
... of claudin-5 with schizophrenia in the general population were weak, our studies here showing a nominal association in a cohort of individuals with 22q11DS with a single remaining claudin-5 ...
12
Original Article Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues
... Hence, claudin proteins are organized into multimolecular complexes, and the activa- tion of signaling pathways [28, ...the claudin protein family has been reported to par- ticipate in ...of ...
8
A New Explanation of Inflammation in Rheumatoid Arthritis Patients With Respect to Claudin-5, Matrix Metalloproteinase-9, and Neuroserpin
... NSP, a natural inhibitor of tPA, was significantly increased in RA and strongly associated with the level of MMP-9 in RA patients in our study. Figure 1. Relationship between (a) claudin-5, (b) MMP-9 and ...
7
Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways
... of Claudin-5 in a cell alters levels of integrins and other ad- hesion-related proteins, thus changing the adhesion of the cancer cell when compared to the ...whether Claudin-5 might be ...
18
Claudin 5: Gatekeeper of neurological function
... of claudin-5 and ZO-1 were observed in the ...of claudin-5 within 12 h of kainic acid injection with increased levels observed after 3 ...days, claudin-5 in the vasculature ...
15
Original Article Tripterygium hypoglaucum (Levl.) Hutch attenuates oleic acid-induced acute lung injury in rats through up-regulating claudin-5 and ZO-1 expression
... mouse claudin-5 monoclonal antibody (1:200; Abcam; Cambridge, MA, USA) and rabbit anti- mouse ZO-1 polyclonal antibody (1:400; Ab- cam; Cambridge, MA, USA) at 4°C overnight, while negative controls were ...
14
Developmental Profile of Claudin-3, Claudin-5, and Claudin-16 Tight Junction Proteins in the Chick Intestine.
... Magnesium and calcium: Mg ++ is the fourth most abundant intracellular cation and the second most abundant divalent cation, coming after Ca ++ (See review for Quamme and Rouffignac, 2000). Mg ++ plays a crucial role as ...
110
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB
... Background: The blood-brain barrier (BBB) strongly restricts the entry of anti-glioma drugs into tumor tissues and thus decreases chemotherapy efficacy. Malignant gliomas are highly invasive tumours that use the ...
17
RETRACTED ARTICLE: Differences in the expression profiles of claudin proteins in human nasopharyngeal carcinoma compared with non-neoplastic mucosa
... follows: claudin-2 for- ward primer (5′-CCAACCTCAGCCAGAGAGAGG-3′) and claudin-2 reverse primer (5′-TCCCCAAACCCAC- TAATCACA-3′); claudin-5 forward (5′-CCTTCATCGG- ...
9
Enhanced expressions of neurodegeneration associated factors, UPS impairment, and excess Aβ accumulation in the hippocampus of mice with persistent cerebral toxocariasis
... (TG2), claudin-5, substance P (SP) and interleukin (IL)-1 β , and the ubiquitin-proteasome system (UPS) function in the hippocampus and associated cognitive behavior in ICR mice orally inoculated with a ...
14
Novel Role of MCP-Induced Protein 1 in Ischemic Brain Damage in Animals of Transient Focal Ischemia
... levels of ZO-1 and claudin-5 were significantly lower in Mcpip1-/- mice as compared to 209. that of wild type after 2 hour ischemia followed by 24 hours reperfusion[r] ...
10
Enhancement of Blood-Brain Barrier Permeability and Reduction of Tight Junction Protein Expression Are Modulated by Chemokines/Cytokines Induced by Rabies Virus Infection
... To decipher the pathway(s) by which chemokines/cytokines reduce the expression of TJ proteins, molecular networks associ- ated with differentially expressed genes were analyzed in the pres- ent study. In mice infected ...
13
Bacterial induction of Snail1 contributes to blood brain barrier disruption
... Invitrogen); claudin 5 (1:1,000; catalog ABT45; EMD Millipore); pan-cadherin (1:1,000; catalog 4068; Cell Signaling Technology); and Snail1 (1:1,000; catalog ab85931; ...
12
Tight junction structure, function, and assessment in the critically ill: a systematic review
... of claudin-5, ZO-1, occludin, and zonulin in each ...of claudin-5 and JAM-A are elevated and correlate with ...serum claudin-5 in hemorrhage conversion of ischemic stroke ...
18
Original Article Tightness comparison of ECV304 cells grown on two different types of transwell inserts
... and claudin-5 are transmembrane proteins, and they interact with the corresponding proteins on adjacent endothelial cells to seal the intercellular cleft, resulting in the limited paracellular permeabili- ...
6
Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke
... [47]), Claudin-5 (1:500, ThermoFisher 35–2500), ZO-1 (1:500, ThermoFisher 61–7300), and anti-GAPDH (1:1000, Abcam AB9484)] over night at 4 °C, followed by appropriate horseradish peroxidase-conjugated ...
18