Claudin-7
Original Article Expression of Claudin-7 in Benign Kidney and Kidney Tumors
... of claudin-7 was increased in chromophobe renal cell carcinoma in a recent oligonucleotide microarray ...of claudin-7 in benign and neoplastic kidneys by immunohistochemical ...for ...
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Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors
... that claudin 7 is exclu- sively located in non-tight-junction regions of mammary and renal epithelial cells [7] suggests that claudins might have functions other than the regulation of tight-junction ...
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Claudin-7 promotes the epithelial – mesenchymal transition in human colorectal cancer
... cld7: claudin-7, CoCa: colon cancer, EMT: epithelial mesenchymal transition, EpC: EpCAM, EpIC: EpCAM intra cellular domain, GEM: glycolipid- enriched membrane domains, IP: immunoprecipitation, iv: intrave ...
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Original Article Upregulation of fibronectin, vitronectin and claudin-7 in cervical cancer
... and claudin-7 in CC ...and claudin-7 were not correlated with any of the recording clinical characteristics, except that higher vitronectin was negatively correlated with ...
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The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities
... Palmitoylated claudin-7 and invasion (a) HEK cells were seeded in matrigel-coated transwell plates, matrigel invasion (recovery within the matrigel) and penetration (recovery at the lower site of the ...
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Emerging clinical significance of claudin-7 in colorectal cancer: a review
... after claudin-7 knockdown, and E-cadherin was significantly ...low claudin-7 expression induced mesenchy- mal–epithelial transition (MET), and the cell migration and invasion potential was ...
12
<p>Non-tight junction-related function of claudin-7 in interacting with integrinβ1 to suppress colorectal cancer cell proliferation and migration</p>
... CRC, claudin-7 might regulate the proliferation and migration of tumor cells through interac- tion with integrin β ...of claudin-7 and integrin β 1 on the cell membrane of HCT116NC cells and a ...
9
<p>MiR-1193 Inhibits the Malignancy of Cervical Cancer Cells by Targeting Claudin 7 (CLDN7)</p>
... Through the above expression and function studies, we con- cluded that miR-1193 was an important tumor suppressing miRNA in CC. However, the mechanism about how miR- 1193 exerted tumor suppressing activities was unknown ...
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Involvement of claudin 7 in HIV infection of CD4( ) cells
... nef (222 bp), and insertion of the EGFP gene, as previous described [20]. At 16 hours post-transfection, medium containing the plasmid was removed from transfected cell cultures. The transfected cell cultures were then ...
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Original Article Changes in the phosphorylation of claudins during the course of experimental colitis
... phorylated claudin-6 (Figure 2G-I). Immuno- staining of phosphorylated claudin-7 was detected in the colon and distributed in the colonic epithelium at the tip of crypts and in the luminal colonic ...
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Matriptase mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis
... and claudin-7 that relates to IEC homeostasis and ...protein claudin-7. EpCAM stabilizes claudin-7 in IECs, and HAI-2 regulates the cell surface serine protease matriptase, a ...
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Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung
... airways. Claudin-1 was expressed moderately or strongly in the epithelium of bronchi and bronchioles, whereas alveolar epithelium was negative (Fig ...2A). Claudin-3, claudin-4 and ...
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Original Article The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues
... parallelly, claudin-7 has also been found to be reduced in invasive breast cancer ...several claudin proteins are often up-regulated in certain ...that claudin-3 and claudin-4 was ...
7
Original Article Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues
... proteins claudin-5, -7, -8 and -9 in the adjacent non-neoplastic tissues and cervical carcinoma tissues, 72 cervical carcinoma tissues and the samples of non-neoplastic tissues adjacent to the tumors were ...
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Original Article Somatostatin regulates tight junction proteins expression in colitis mice
... Tight junctions are located apically in the inter- cellular junctions, and they contribute to main- taining homeostasis in the intestinal lumen. Multiple proteins that form the tight junction have been identified, ...
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Original Article Claudins 1, 2, 3, 4, 5 and 7 in solar keratosis and squamocellular carcinoma of the skin
... and claudin 1 knockout mice die of dehydration [35]. In our series claudin 1 was strongly exp- ressed in normal epidermis and decreased in solar keratosis and squamocellular carcino- ...epithelia. ...
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Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways
... between Claudin-5 and N-WASP or Claudin-5 and ROCK 1 as well as whether any dir- ect effect was occurring at the protein level of these molecules in the control and transfected ...with Claudin-5, ...
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Pfefferle_unc_0153D_15508.pdf
... murine claudin-low ...a Claudin-low Ex BALB/c Trp53 -/- tumor (753R), which maintains its claudin-low expression features even after multiple transplant passages ...human claudin-low subtype, ...
185
Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus
... Identification of amino acid residues in CLDN9 critical for HCV entry. Although CLDN3 shared the highest EL1 homol- ogy to CLDN6 and CLDN9, it was unable to serve as an HCV coreceptor. Comparison of EL1 sequences was ...
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Regulated expression of claudin 4 decreases paracellular conductance through a selective decrease in sodium permeability
... of claudin-4–overexpressing cell lines, trans- fected MDCK cells were plated in twelve-well dishes on Trans-well ...days; claudin-4 protein levels were always compared with that seen in unin- duced cells of ...
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