Cleavage and polyadenylation
Identification and Characterization of Two Internal Cleavage and Polyadenylation Sites of Parvovirus B19 RNA
... additional cleavage site at nt 2840 (labeled b ⬘ in ...mutant, cleavage was directed by both core se- quences at approximately equal ...downstream cleavage site b ⬘ ...of cleavage and ...
6
Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation
... and polyadenylation gives rise to transcripts with var- ied 3′-UTR lengths and in some cases an altered reading frame, a process known as alternative polyadenylation (APA) (6, ...recognition, ...
17
Stiff matrix instigates type I collagen biogenesis by mammalian cleavage factor I complex-mediated alternative polyadenylation
... endonucleolytic cleavage and addition of a poly(A) tail at the 3′ end of ...Constitutive polyadenylation occurs in pre-mRNAs with a single encoded cleavage and polyadenylation ...potential ...
16
Direct Interactions between the Paf1 Complex and a Cleavage and Polyadenylation Factor Are Revealed by Dissociation of Paf1 from RNA Polymerase II
... the cleavage and polyadenylation factors with chromatin ...for cleavage and polyade- nylation factors, but the defects we and others have observed in 3 ⬘ -end formation in the absence of the Paf1C ...
10
HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6
... doi:10.1128/JVI.06607-11 jvi.asm.org 3851 Downloaded from http://jvi.asm.org/ on November 7, 2019 by guest The antiviral factor CPSF6-358 restricts human immunodeficiency virus type 1 HI[r] ...
10
Alternative cleavage and polyadenylation of genes associated with protein turnover and mitochondrial function are deregulated in Parkinson’s, Alzheimer’s and ALS disease
... Raw sequencing data in the form of FASTQ files and alignment information was downloaded from the Se- quence Read Archive (SRA). GEO Accession numbers of datasets used are outlined in Table 1. FASTQ files were groomed and ...
14
Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control
... alternative polyadenylation (SAAP) method to identify significantly regulated APA events, as previously described ...tive polyadenylation (GAAP) was previously described in ...
17
Twist of messenger Fate: novel mechanisms for TDP43 in modulating mRNA decay and alternative polyadenylation
... and polyadenylation site selection in mammalian pre-mRNAs is controlled by cis- acting RNA elements and trans-acting factors (Figure ...The polyadenylation signal (PAS) represents the leading cis-element; ...
91
Minute Virus of Canines NP1 Protein Interacts with the Cellular Factor CPSF6 To Regulate Viral Alternative RNA Processing
... which cleavage and polyadenyl- ation events for (pA)p, we made mutations of these motifs either individually or in combination ...internal polyadenylation was again significantly diminished, and ...
18
Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs
... follow cleavage and ...3=-end polyadenylation but not when bound to internal ...inefficient polyadenylation is associated with impaired recruitment of splicing factors to affected introns, which are ...
13
Sequences regulating poly(A) site selection within the adenovirus major late transcription unit influence the interaction of constitutive processing factors with the pre-mRNA.
... endonucleolytic cleavage of the nascent transcript followed by rapid addition of poly(A) to the newly formed 3 9 end (for reviews, see references 24, 46, and ...the cleavage event is directed by two RNA ...
9
A block in full-length transcript maturation in cells nonpermissive for B19 parvovirus.
... To characterize the activity of B19 virus cleavage and polyadenylation signals in isolation, we constructed expression plasmids linking the middle or end 3' processing regions to fragmen[r] ...
7
Regulation of Human Papillomavirus Type 31 Polyadenylation during the Differentiation-Dependent Life Cycle
... early polyadenylation signals and proceeds to a poly(A) site downstream of ...differentiation-dependent polyadenylation and read-through in ...of polyadenylation sites in undifferentiated ...for ...
8
Mollison_unc_0153D_16545.pdf
... stimulate polyadenylation in mammals ...induce cleavage and polyadenylation in the absence of a canonical poly(A) signal, and inefficient poly(A) tail addition leads to the degradation of these ...
82
Specificity factors in cytoplasmic polyadenylation
... the cleavage site. 5,14 A fourth sequence element contributing to cleavage site recognition is a G rich sequence down- stream of the DSE, for which the binding factor has not yet been ...
25
Molecular Characterization of Proteolytic Processing of the Gag Proteins of Human Spumavirus
... Analysis of peptide 4 illustrates the approach taken (Table 1). In the MALDI mass spectrum of the 11-mer peptide 4, a molecular ion at m/z 1,236.3 was observed in the control di- gestion with the enzymatically inactive ...
5
Characterization of the polyadenylation signal of influenza virus RNA.
... Instead, sequence analysis of influenza virus vRNAs shows that the 3' and 5' terminal sequences form a panhandle structure 2, 6, 16, 19, and it has been postulated that this duplex struc[r] ...
5
Geology, geochronology and structural evolution of La Escondida copper district, Northern Chile
... Cleavage Cleavage Cleavage Cleavage Cleavage Bedding Bedding Bedding Dyke Dyke Dyke Dyke Dyke Dyke Dyke Reverse fault Reverse fault Reverse fault Reverse fault Reverse fault Reverse faul[r] ...
163
Polyadenylation of Vesicular Stomatitis Virus mRNA
... In this report, we demonstrate that the virion RNA does -not contain polyuridylic acid [polyU ] sequences corresponding in length to the polyA in the transcription product, and show that[r] ...
6
Polyadenylation sites for influenza virus mRNA.
... The analysis described in this report demonstrates that in at least four of the eight RNA segments of the influenza virus genome, the tract of uridine residues common to each segment of [r] ...
7