Clock gene
The association of inherited variation in the CLOCK gene with breast cancer tumor grade
... The CLOCK gene is the master circadian regulator and key to the maintenance of our circadian ...this gene affect the length of the rhythm period and change the circadian rhythm ...The CLOCK ...
6
Clock gene Per2 as a controller of liver carcinogenesis
... other clock genes through the interaction of their protein heterodimers with the CLOCK::BMAL1 protein heterodimer or clock gene promoters ...
16
The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells
... various clock genes in normal cells, through their interaction, establish a number of positive and negative feedback loops that compose a network ...of clock gene PER1 is decreased in many types of ...
13
Expression of circadian clock gene human Period2 (hPer2) in human colorectal carcinoma
... of clock gene expression was due to DNA methylation of the promoters rather than gene mutations of the clock ...Period gene family using a forward genetic screen, unveiling a new ...
8
Clock gene Per2 as a controller of liver carcinogenesis
... other clock genes through the interaction of their protein heterodimers with the CLOCK::BMAL1 protein heterodimer or clock gene promoters ...
17
Phototransduction and clock gene expression in the troglobiont beetle Ptomaphagus hirtus of Mammoth cave
... circadian clock genes is restricted to small cell groups in the brain (Tomioka and Matsumoto, ...of clock genes in ...and clock gene expression using a very marginally cell type-enriched ...
10
Light and Clock Expression of the Neurospora Clock Gene frequency Is Differentially Driven by but Dependent on WHITE COLLAR-2
... circadian clock by acting through heterodimers of the WHITE COLLAR-1 and WHITE COLLAR-2 proteins to induce transcription of the frequency ...this clock gene were strongly ...and clock-driven ...
10
The Expression of Circadian Clock Gene Promoters in Arabidopsis Callus.
... containing clock gene promoters fused to luciferase gene by Agrobacterium transformation and callus induction from seedlings and setting the system for detecting bioluminescence to determine the ...
72
Daily rhythm variations of the clock gene <em>PER1</em> and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma
... the clock gene PER1 and cancer-related CCGs involved in the stages of carcinogenesis and the development of carcinoma are ...of clock gene PER1 and cancer-related genes VEGF, KI67, C-MYC, and ...
8
The Clock Gene period of the Housefly, Musca domestica, Rescues Behavioral Rhythmicity in Drosophila melanogaster: Evidence for Intermolecular Coevolution?
... CRYPTOCHROME. Science 285: 553–556. Lee, C., K. Bae and I. Edery, 1998 The Drosophila CLOCK protein Citri, Y., H. V. Colot, A. C. Jacquier, Q. Yu, J. C. Hall et al., undergoes daily rhythms in abundance, ...
12
Lack of association between cluster headache and PER3 clock gene polymorphism
... internal clock cycle is reset every day by sev- eral external factors, of which light is the most im- ...the clock gene PERIOD3 (PER3, rs57875989) has been shown to correlate with diurnal preference ...
6
The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity
... These cKO mice were crossed onto a PER2::luc reporter back- ground (25) for the tracking of circadian clock activities. Real-time photon counting and bioluminescence imaging confirmed the loss of circadian rhythms ...
13
The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition
... Circadian clock has been implicated in regula- tion of drug metabolism and detoxification ...Circadian clock regulates drug detoxification through modulation of expressions of XMEs ...Several clock ...
14
Transcription factor interactions at the promoter of the Arabidopsis circadian clock gene LHY
... of clock-controlled ...the clock-regulated CAB2 and TOC1 promoters (Green & Tobin, 1999, Alabadi et ...the clock: with LHY and CCA1 found to repress TOC1 expression, and TOC1 required for ...
199
Analysis of circadian clock gene BMAL1 in Pakistani
... cataract families to identify the novel pathogenic variants in the BMAL1 gene.. We have studied 21.[r] ...
8
Rhythmic profiles of cell cycle and circadian clock gene transcripts in mice: a possible association between two periodic systems
... The overall rhythm pattern of the cell cycle is determined by the tissue’s circadian clock and modified by developmental programming, illumination and metabolic (feeding) cycles (Borgs et al., 2009; Kondratov et ...
7
Effects of Psychosocial Stress on the Gene Expression of the Clock Genes hPER1 and hPER2 in Humans
... of clock gene expres- sion (Balsalobre et ...of clock genes ...of gene expression over two hours post-stress; therefore, we might have missed a possible later increase or change of the ...
8
The circadian gene Clock is required for the correct early expression of the head specific gene Otx2
... ABSTRACT The circadian cycle is a universal molecular mechanism for imposing cyclical control on cellular processes. Here we have examined the role of one of the crucial circadian genes, Clock, in early Xenopus ...
6
“Circadian System and Bipolar Disorder” by Bhagya Rajendrana, Chitra Loganathan, India.
... circadian clock genes. At cellular level, oscillation of various clock genes required for maintenance of biological rhythms to an approximate 24 hour cycle is generated by transcriptional autoregulatory ...
9
The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit
... The mutant allele thus competes with the wild-type allele of the gene in the generation of circadian rhythms, providing strong evidence that the Clock gene is an essenti[r] ...
12