clock genes
Body weight, metabolism and clock genes
... the clock genes [3,5]. The clock genes codify a family of proteins that generate an auto-regulatory mechanism of positive and negative transcriptional feedback loops which occur on a 24-hour ...
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Functional circadian clock genes are essential for the overwintering diapause of the Northern house mosquito, Culex pipiens
... circadian clock consists of a self-regulatory negative feedback loop (Hardin, ...circadian clock, the proteins CLOCK (CLK) and CYCLE (CYC), bind to E- box promoter regions of other circadian ...
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Effects of Psychosocial Stress on the Gene Expression of the Clock Genes hPER1 and hPER2 in Humans
... In any case, a sudden increase of cortisol seems to affect the mRNA levels of both hPER1 and hPER2 in the periphery or at least in oral mucosa, albeit the effect is not as pronounced as in animal studies which report an ...
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The rhythmic expression of clock genes attenuated in human plaque-derived vascular smooth muscle cells
... rhythms, Clock mutant and Bmal1-knockout, pathological remodeling and vascu- lar injury (such as intimal hyperplasia) ...of clock genes are significant decreased in human plaque- derived VSMCs ...
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Postnatal ontogenesis of clock genes in mouse suprachiasmatic nucleus and heart
... core clock genes which is Clock gene, Bmal1 gene, three Period genes(Per1, Per2, Per3), two Cryptochrome genes(cry1, cry2), CKIε and Rev-Erba ...
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Unproductive alternative splicing and nonsense mRNAs: A widespread phenomenon among plant circadian clock genes
... of clock genes is demonstrated beyond ...in clock regulation remains a hypothesis, and the authors are quite careful ...in clock genes to the overall background in Arabidopsis? Is it ...
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Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells
... apoptosis-related genes and fibrinolytic-related genes are controlled by core clock genes like Bmal1, CLOCK, Per2, Cry1 and Rev-erb α [23 – ...of clock genes we reported ...
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Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study
... and CLOCK genes with CH in Chinese Han ...HCRTR2 genes, and revealed obvious difference for the polymorphisms of the HCRTR2 rs2653349 loci between case and control ...
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A laboratory simulation of Arabidopsis seed dormancy cycling provides new insight into its regulation by clock genes and the dormancy related genes DOG1 , MFT , CIPK23 and PHYA
... Footitt, Steven, Ölcer-Footitt, Hülya, Hambidge, Angela J. and Finch-Savage, William E.. (2017) A laboratory simulation of Arabidopsis seed dormancy cycling provides new insight into its regulation by clock ...
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Photoperiodic diapause under the control of circadian clock genes in an insect
... dian clock regulating the cuticle deposition ...circadian clock in distinct ...circadian clock genes: per RNAi induced ovarian development even under short-day conditions, whereas cyc RNAi ...
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THE IMPACT OF PHYSICAL EXERCISE ON THE SKELETAL MUSCLE CLOCK GENES
... core clock gene identified impairments in skeletal muscle glucose ...circadian genes involved in glucose utilization and adrenergic signaling; and accompanied by increases in expres- sion of lipogenic ...
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Deregulated expression of circadian clock genes in gastric cancer
... In this study, we observed an up-regulation of PER2 in GCs. PER2 play an important role in tumor suppression and DNA damage response in vivo [27]. Our previous studies have revealed down-regulation of PER2 in HCC [18], ...
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<p>The role of circadian clock genes in tumors</p>
... circadian clock participates in tumorigenesis by regulating downstream tumor-related ...these genes impacts tumor cell proliferation, apoptosis, migration, and ...Silencing Clock diminishes the ...
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Critical cholangiocarcinogenesis control by cryptochrome clock genes
... Circadian disruption induced by Per2 mutation, constant light or chronic jet lag exposure has been shown to promote DEN-induced liver carcinogenesis, resulting in increased formation of a majority of HCC and few CCA in ...
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Clock genes and their genomic distributions in three species of salmonid fishes: Associations with genes regulating sexual maturation and cell cycling
... NPAS2 genes exist in vertebrates (a teleost-specific form and Sarcopterygian form) with the teleost-specific form more closely related to Clock3 and Clock1 vertebrate genes [see data for family TF324568 in: ...
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The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma
... Clock genes sustain organismal circadian rhythm and regulate downstream CCGs to affect cellular activities [2, 5, 11-13, 18, 20, ...cycle genes, including CyclinB1, CyclinD, CyclinE, WEE-1 and p21, ...
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Impact of chronically alternating light-dark cycles on circadian clock mediated expression of cancer (glioma)-related genes in the brain
... and clock disruption is yet to be understood ...core clock genes seem essential in ...circadian clock, is an endogenous timekeeping system which further controls many peripheral clocks in the ...
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Identification of Circadian-Clock-Regulated Enhancers and Genes of Drosophila melanogaster by Transposon Mobilization and Luciferase Reporting of Cyclical Gene Expression
... these clock genes, period (per) and Not all clock components exhibit daily fluctuations in timeless (tim), begin to be transcribed in the late morn- their abundance: Products of the cyc and dbt ...
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Creating The Water Clock
... his recommendation. He believed the scene was too naked in terms of sound, but I believe minimalistic soundscape can help add realism and tension in a drama. Immediately after this scene there was another chance to do a ...
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On the Overdispersed Molecular Clock
... T h e possibility that each substitution in a gene changes the degree of selective constraints (neutral space) is analyzed as a time-dependent renewal process. In the[r] ...
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