closed circular
Properties of Closed Circular DNA
... A method for the measurement of the superhelix density, a 0 , of a closed circular DNA from the separation between fluorescent buoyant bands of nicked and closed circul[r] ...
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Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein
... 12 Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein䌤 Weifan Gao and Jianming Hu* Department of Microbiology and Immunology, The Pennsylvani[r] ...
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Serum Hepatitis B Virus DNA, RNA, and HBsAg: Which Correlated Better with Intrahepatic Covalently Closed Circular DNA before and after Nucleos(t)ide Analogue Treatment?
... Dynamic changes in serum HBV RNA, HBV DNA, HBsAg, and HBeAg levels during the 96-week NUC treatment. The dynamic changes in serum HBV RNA, HBV DNA, HBsAg, and HBeAg levels during the 96-week NUC treatment are shown in ...
11
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization.
... 795-809 0022-538X/79/09-0795/10$02.00/0 Molecular Cloning of the Harvey Sarcoma Virus Closed Circular DNA Intermediates: Initial Structural and Biological Characterization Received for p[r] ...
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Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus.
... relaxed circular, partially double- stranded DNA genome of about 3 ...covalently closed circular (ccc) DNA during initiation of infection (17, ...relaxed circular viral DNA, takes place in ...
8
Acquisition of Sequences Homologous to Host Deoxyribonucleic Acid by Closed Circular Simian Virus 40 Deoxyribonucleic Acid
... Homology to host DNA of closed circular SV40 DNA extracted from BS-C-I cells infected with undiluted, serially passaged, plaque-purified virusa Virus used for infection Per cent 'H-DNA b[r] ...
8
I. A study by electron microscopy of the RNA and RNA-DNA hybrids of HeLa mitochondria. II. Replication of closed circular mitochondrial DNA in mouse L cells
... ation of subcellular components from poliovirus- infccted and normal He La cell s. Interaction of HeLa cell proteins with RNA. The int e raction of closed circular DNA[r] ...
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PCR mediated recombination impacts the analysis of hepatitis B Virus covalently closed circular DNA
... Incoming partly double stranded hepatitis B virus (HBV) DNA genomes are completed by the viral polymerase generating relaxed circular DNA (rcDNA). Following translocation to the nucleus, the gaps are repaired by ...
5
Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation
... relaxed circular partially double-stranded DNA (rcDNA; ...covalently closed circular DNA (cccDNA), which serves as the template for the transcription of viral RNAs (3, 31, ...
13
Monomer and multimer covalently closed circular forms of Rous sarcoma virus DNA.
... 148 du Centre National de la Recherche Scientifique, Institute of Cancerology and Immunogenetics, Villejuif, France Covalently closed circular molecules of viral DNA synthesized in virus[r] ...
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Characterization of Nucleosome Positioning in Hepadnaviral Covalently Closed Circular DNA Minichromosomes
... covalently closed circular DNA (cccDNA) exists as an episomal minichromosome in the nucleus of virus-infected hepatocytes, and serves as the transcriptional template for the synthesis of viral ...
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Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification.
... We have previously shown that within the first 4 days after infection of primary duck hepatocytes by the duck hepatitis B virus DHBV, the amount of cccDNA in the infected cells increased[r] ...
6
Molecular cloning of covalently closed circular DNA of bovine leukemia virus.
... Comprehensive restriction endonuclease mapping of the unintegrated bovine leukemia virus and the cloned DNA molecules showed that eight of the nine clones carried viral information witho[r] ...
5
Mechanism of Replication of Single-Stranded φX174 DNA VII. Circularization of the Progeny Viral Strand
... This experiment shows that linear strands isolated from particles produced in the ligase-deficient host are intrinsically capable of becoming covalently closed circular SS DNA, but only [r] ...
11
Degradation of the viral strand of phiX174 parental replicative-form DNA in a rep- host.
... Concomitant with this degradation, replicative intermediates are formed which sediment at 21s, the rate of RF I supercoiled-closed circular DNA, in a neutral sucrose gradient but which d[r] ...
6
Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA
... Abbreviations ALT: Alanine transaminase; CAS: CRISPR-associated; cccDNA: covalently closed circular DNA; CI: Confidence interval; CMV: Cytomegalovirus immediate early promoter/enhancer; [r] ...
10
Circular RNA ABCB10 promotes hepatocellular carcinoma progression by increasing HMG20A expression by sponging miR-670-3p
... It is worth noting that the study of previous tumor metastasis in the world mainly focused on the study of proteins and their coding genes, while ignoring the role of non-coding genes (Non-coding RNA, nc RNA) in tumor ...
11
New perspectives on the hepatitis B virus life cycle in the human liver
... al. developed novel molecular diagnostic tools for examining HBV DNA (covalently closed circular DNA [cccDNA] and pro- tein-free relaxed circular DNA [rcDNA]), RNA, and protein in the same liver sec- ...
5
Molecular cloning of biologically active proviral DNA of the anemia-inducing strain of spleen focus-forming virus.
... To simplify the comparison between the permuted cloned viral DNA and the closed circular form of SFFVA proviral DNA, ClaI digestion of clone 1310 DNA was used to separate viral sequences[r] ...
10
Electrophoretic characterization of intracellular forms of bacteriophage phi X174 DNA: identification of novel intermediate of altered superhelix density.
... Electrophoretic analysis of RF DNA after controlled denaturation suggests the existence of four populations of closed circular RF: i molecules of native superhelix density RFI; ii a popu[r] ...
11