clotting factors
Mechanism of the anticoagulant effect of warfarin as evaluated in rabbits by selective depression of individual procoagulant vitamin K dependent clotting factors
... dependent clotting factors to the ability of warfarin to protect rabbits against tissue factor- induced ...procoagulant factors were determined, in assays with rabbit substrates, for a group of ...
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Hereditary combined deficiency of the vitamin K-dependent clotting factors
... K-dependent clotting factors deficiency (VKCFD) is a rare congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X as well as natural ...
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Synthesis of clotting factors by the isolated perfused rat liver
... The slight shortening of the Factor X assay clotting time is surmised to reflect the absence of Factor X activity in adsorbed rat serum sample 1 and the presence of some Factor X activi[r] ...
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Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family
... This studywas performed to establish evidence for a genetic basis for plasma concentrations of hemostatic markers known to confer risk of thrombosis. The highest heritabilityestimates were found for the measures of ...
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THE EFFECT OF GLASS UPON THE ACTIVITY OF THE VARIOUS PLASMA CLOTTING FACTORS
... Therefore, a difference in the clotting times of "silicone" and "glass activated" plasma with excess strong brain thromboplastin, as in a Quick "prothrombin time," must mean that glass a[r] ...
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Consumption coagulopathy in acute aortic dissection: principles of management
... of clotting factors and fibrinogen ultim- ately lead to coagulopathy and DIC, which was consist- ent with our previous findings ...massive clotting factor consumption is one of the causes of ...
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EFFECT OF AQUEOUS LEAF EXTRACT OF TRIDAX PROCUMBENS ON BLOOD COAGULATION
... and clotting times obtained with the extract are approximately one half of their respective observed values without application of the extract to wound or blood ...the clotting cascade may have been ...the ...
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Marieb_ch10 (1).ppt
... thromboplastin, blood protein clotting factors, and calcium ions to trigger a clotting cascade. Thrombin joins fibrinogen proteins into[r] ...
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Congenital Deficiency of α2 Plasmin Inhibitor Associated with Severe Hemorrhagic Tendency
... known clotting factors, platelet glass bead retention, Factor VIII-related antigen, platelet aggregation by ADP, collagen and ristocetin, and clot ...
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WARFARIN RESISTANCE MECHANISMS AND MANAGEMENT
... Mechanism of Action of Warfarin: Warfarin and related 4- hydroxycoumarin- containing molecules decrease blood coagulation by inhibiting vitamin K epoxide reductase, an enzyme that recycles oxidized vitamin K to its ...
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The measurement of thrombin in clotting blood by radioimmunoassay
... the clotting factor structurally most similar to ...in clotting blood in polypropylene tubes and observed that thrombin appears (approximately equal to 3 ng/ml) within 45 S-5 min after ...in clotting ...
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Partial purification and characterization of contact activation cofactor
... intrinsic clotting involves Factor XI, Factor XII, Fletcher factor, and a fourth activity that we call contact activation cofactor ...of Factors XI and XII, and Fletcher ...
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A Case of Alveolar Bleeding from Clotting Abnormality by Cefmetazole
... to clotting abnormality following the use of cefmetazole, one of cephalosporins containing an N- methylthiotetrazole (NMTT) side ...K-dependent clotting factors via inhibition of the vitamin K ...
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Evaluation of clotting factor activities early after severe multiple trauma and their correlation with coagulation tests and clinical data
... VIII, clotting factor activities were generally reduced in the early time period following ...with clotting factor activities is somewhat contrary to the con- cept of shock induced coagulopathy also ...
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Anticoagulant synergism of heparin and activated protein C in vitro Role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C
... one-stage clotting time of normal plasma was markedly en- hanced by addition of purified APC to the ...purified clotting factors showed that heparin enhanced by fourfold the phospholipid-dependent ...
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THE SITE OF INHIBITION OF BLOOD CLOTTING BY SOY BEAN TRYPSIN INHIBITOR
... Determination of prothrombin: The amount of active prothrombin being used in a given experiment was checked by using a 1/25 dilution of purified stock beef lung thromboplastin and a 1/10[r] ...
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THE CLOTTING BEHAVIOR OF HUMAN “PLATELET FREE” PLASMA: EVIDENCE FOR THE EXISTENCE OF A “PLASMA THROMBOPLASTIN”
... Three of these patients had marked prolongation of their whole blood clotting times and in each of these instances the "platelet-free" plasmas were spontaneously incoagulable in glass an[r] ...
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Selection of Tissue Factor-Deficient Cell Transplants as a Novel Strategy for Improving Hemocompatibility of Human Bone Marrow Stromal Cells
... All clotting parameters were cell dose- dependent to a variable ...reduced clotting time and faster fibrin deposition (higher α -angle) in the presence of WAT and UC stromal cells compared to BMSCs at all ...
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ENZYMES AND BLOOD CLOTTING I TRYPSIN AS AN ACCESSORY FACTOR
... time PT, after Quick, Stanley-Brown and Bancroft 12; 4 Ca-cephalin-plasma clotting time PTT, after Langdell and co-workers 13, using substrate plasmas from a normal N, b hemophilic VIII-[r] ...
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PLATELET PHOSPHATIDES THEIR FATTY ACID AND ALDEHYDE COMPOSITION AND ACTIVITY IN DIFFERENT CLOTTING SYSTEMS
... The results with platelet and brain PI, containing small amounts of PS, were striking in that these showed excellent activity in both the TGT and recalcified clotting times.. Lecithin wa[r] ...
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