Co-option
Independent Co Option of a Tailed Bacteriophage into a Killing Complex in Pseudomonas
... The convergence between these two bacteriocins is striking at both the genomic and molecular levels. Given that the R-type syringacin region is located in at least three (possibly four) distinct genomic locations across ...
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Co-option of Liver Vessels and Not Sprouting Angiogenesis Drives Acquired Sorafenib Resistance in Hepatocellular Carcinoma.
... vessel co-option in a second sorafenib- resistant orthotopic model using MHCC-97H cells (data not shown); therefore, this phenomenon may be applicable to other ...
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Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases.
... HGP. Co-option of sinusoidal vessels by invading cancer cells is ...HGP. Co-option of sinusoidal vessels by cancer cells is physically precluded by the desmoplastic stroma (DS) that separates ...
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Revisiting tumor angiogenesis: vessel co-option, vessel remodeling, and cancer cell-derived vasculature formation
... vessel co‑option, vessel remodeling, and tumor cell‑derived vasculature ...Vessel co‑option may occur in tumors independently of sprouting angiogenesis, and sprouting angiogenesis is not ...
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The skeletal proteome of the coral Acropora millepora: the evolution of calcification by co-option and domain shuffling
... In corals, biocalcification is a major function that may be drastically affected by ocean acidification (OA). Scleractinian corals grow by building up aragonitic exoskeletons that provide support and protection for soft ...
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His Feminist Facade: The Neoliberal Co-option of the Feminist Movement
... We first explore the evolution of the second-and third-wave feminist movements, demonstrating how the “sex work” perspective developed in opposition to the feminist faction advocating to end pornography and prostitution. ...
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Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models.
... vessel co-option has been proposed as a mechanism that could drive resistance to anti-angiogenic ...vessel co-option has not been extensively studied in lung metastases, and its potential to ...
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Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis
... component. It is known that metastatic tumors grow in the mesentery at an accelerated rate and contain a high density of microvessel [39]. The high density of microvessel in adipose tissues would provide vascular niches ...
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Co option of the PRDM14 CBFA2T complex from motor neurons to pluripotent cells during vertebrate evolution
... the co-option of PRDM14-TET complex into pluripotent cells might depend on the expression of TET proteins in pluripotent cells during the emergence of ...
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The Concept of Co-option: Why Evolution Often Looks Miraculous
... The co-option of traits to serve new functions is not a difficult concept to ...evolutionary co-option is that we purposefully change an object’s function, while evolution simply takes ...
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Conservation and co-option in developmental programmes: the importance of homology relationships
... been co-opted repeatedly into new regulatory regions or morphological ...of co- option for similar functions, ...expression. Co- option of this pre-existing mechanism into more specific ...
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Evolution: Gene Co option Underpins Venom Protein Evolution
... actually co-expressed in multiple tissue types (albeit at significantly higher levels in the venom gland), providing a framework for exploring how the expression of genes encoding toxic molecules are ...
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Introgression and repeated co-option facilitated the recurrent emergence of C4 photosynthesis among close relatives.
... sequences descending from a single gene in the common ancestor of grasses via speciation and/or duplication were considered as the same gene lineage (i.e., these are grass co-orthologs). These groups include ...
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Amphioxus SYCP1 : a case of retrogene replacement and co option of regulatory elements adjacent to the ParaHox cluster
... only co-opted a bidirectional promoter from the adjacent gene AmphiCHIC, but also evolved a de novo multi-exonic 5′ UTR in order to make use of this ...has co-opted a bidirectional AmphiCHIC pro- moter, ...
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Introgression and repeated co-option facilitated the recurrent emergence of C4 photosynthesis among close relatives.
... phylogenetic tree was inferred using Phyml (Guindon and Gascuel 2003) with a GTR+G+I model, a model that fits the vast majority of genes (e.g., Fisher et al. 2016) and is appropriate to infer a large number of trees. ...
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Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements
... immunofluorescence of 11-β-hydroxylase protein, a specific marker of Leydig cells, was performed (Fig. 6b). Interstitial cells of Leydig are found adjacent to the seminiferous lobules in the testes and produce androgens ...
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Rational design of artificial genetic switches : co option of H NS repressed operons by the VirB virulence master regulator
... B Transcription from derepressedproU promoters is mediated by promoter P2, not P1 Partial de-repression of the proU promoter by VirB The URE and VirB-dependent proU de-repression Osmoreg[r] ...
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Modular co-option of cardiopharyngeal genes during non-embryonic myogenesis
... In order to investigate the mechanisms underlying clonal replication of muscular systems in colonial ascid- ians and infer the origin of muscle precursors during blastogenesis, we selected genes involved in embry- onic ...
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Co-option of a coordinate system defined by the EGFr and Dpp pathways in the evolution of a morphological novelty
... have co-opted novel expression patterns and interactions to provide the main regulatory information for the epithelial positional cues to be translated into a novel morphology, both br, pnt and very likely mirr ...
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Genetic Enablers Underlying the Clustered Evolutionary Origins of C-4 Photosynthesis in Angiosperms
... if co-option of gene lineages was unbiased, by simulating a random recruitment from the total pool of available lineages across the ten gene families, using 100,000 ...of co-ortholog groups in each ...
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