collagen IV
Immunohistochemical Expression of Collagen IV and MMP9 in Odontogenic Cysts and Tumors
... collagen IV. The present study was conducted to analyze the role of collagen IV and its association with matrix metalloproteinases9 in odontogenic cysts and ...method. Collagen ...
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The prognostic value of quantitative analysis of CCL5 and collagen IV in luminal B (HER2–) subtype breast cancer by quantum-dot-based molecular imaging
... Fourth, collagen IV is not tumor-specific, it is a major extracellular matrix constituent, so we did not analyze its prognostic ...and collagen IV and demonstrated the prognostic value of the ...
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RASA1 dependent cellular export of collagen IV controls blood and lymphatic vascular development
... To further understand the role of RASA1 in the BV and LV systems and how its loss may contribute to the vascular pheno- types observed in CM-AVM1, in the current study, we examined the influence of embryonic loss of ...
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A Study to Assess the Significance of Urinary Collagen IV Excretion to Predict Preeclampsia in Early Pregnancy
... As collagen IV is a principal component of glomerular basement membrane and mesengial matrix, many studies have identified the levels of collagen IV in serum and urinary samples are more ...
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The effect of maternal nicotine on basement membrane collagen IV of brain microvessels changes in neonatal Balb/C mice
... with increased premature parturition, the reduction of placental blood flow sudden abortion and sudden infant death syndrome (SIDS) (2, 3). The cardiovascular effects of nicotine results in reduced blood flow to the ...
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Original Article Double immunohistochemical staining with laminin 5 (γ2 chain) and collagen IV in colorectal neoplasms
... cannot be identified in BM due to the strong sheltering capacity of the DAB based chromo- gen Deep Space Black (collagen IV) [26, 27]. Lenander et al. have shown that the expression of laminin 5 in adenomas ...
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A collagen IV–derived peptide disrupts α5β1 integrin and potentiates Ang2/Tie2 signaling
... The total protein levels of Tie2 and its downstream targets remained unchanged for both Ang1 and Ang2 at all concentrations of AXT107 (Supplemental Figure 1, A and B; supplemental mate[r] ...
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TNF-α promotes cerebral pericyte remodeling in vitro, via a switch from α1 to α2 integrins
... The basal lamina of cerebral blood vessels comprises a number of different ECM proteins and proteoglycans, the precise make-up of which varies with the vessel- maturation state. The basal lamina of mature vessels is ...
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Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study
... To evaluate the contents of Langerhans cells, melano- phages, and mature melanocytes, we used antibodies to CD1a, CD68, and NKI/Beteb, respectively. The integrity of the epidermal basal membrane was assessed using a col- ...
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Diagnostic significance of biochemical indicators of liver fibrogenesis in adolescents with obesity
... type IV collagen (Serum collagen IV EIA, Argutus Medical (Japan)) in blood, N - terminal propeptides of type I collagen (NT-proCNP, Biomedica (Aus- tria)) and C-terminal telopeptides of ...
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Prediction of Hepatic Fibrosis in Patients with Chronic Hepatitis C Genotype 4: A non-Invasive biochemical analysis
... (HA), Collagen type IV (Coll-IV), and aspartate aminotransferase (AST) to platelet ratio index (APRI) as non-invasive diagnostic and stratification markers for hepatic ...both ...
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Direct transcriptional regulation of neuropilin 2 by COUP TFII modulates multiple steps in murine lymphatic vessel development
... In contrast, a marked reduction of the expression of LEC markers, such as LYVE1, Nrp2, and VEGFR3, and ectopic expression of BEC markers, endoglin, laminin, collagen IV, and CD34, was ob[r] ...
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Effects of intravitreal injection of netrin-1 in retinal neovascularization of streptozotocin-induced diabetic rats
... type IV + strands in the rats injected with ...type IV + strands than in the PBS-treated rats from 1 to 6 weeks after treatment ...type IV collagen of the four groups at 6 weeks after ...
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Influence of extracellular matrix on the proliferation and adhesion properties of stem cells derived from different sources
... We obtained different results regarding hair follicle stem cells. The adhesion of these cells to culture surfaces was much slower than in other cell types. Moreover, from all analyzed matrix proteins, the adhesion of ...
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... type IV collagen with large interruptions. The areas without collagen IV staining synchronized with areas of highly proliferating malignant cells ...of collagen IV in basement ...
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Sayyed, Sufyan G. (2010): Role of pro-inflammatory and homeostatic chemokines in diabetic nephropathy. Dissertation, LMU München: Medizinische Fakultät
... Chemokine receptor CCR5 gene polymorphism has been reported in Indian patients with ESRD 133 as well as in Japanese diabetic nephropathy patients 134 . Another study has reported overexpression of CCR5 on peripheral ...
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Increased expression of basement membrane collagen in human diabetic retinopathy
... Because collagen type IV is uniquely present in basement membranes and represents their predominant structural element, we studied its expression in retinas obtained postmortem from five patients with 8 +/- ...
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Original Article miR-192-5p, TGFβ2 and the expression of extracellular matrix moieties in of human trabecular meshwork cells
... Several miRNAs, including miR-23, -29, -192, -194, and -215, are highly expressed in the tra- becular meshwork [22-26] which are associat- ed with fibrosis of the kidney, lung and liver [27, 28]. Overexpression of ...
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Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway
... However, collagen IV expression was still detected in the granulosa cells (data not shown), indicating that additional signaling pathways may be involved in the process of altered ECM deposition in response ...
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Production and Characterization of Recombinant Rat Non Collagen Domain of α3 Chain of Type IV Collagen α3 (IV) NC1 Antigen
... that 3.2% American had been diagnosed one of 24 autoimmune diseases. The most common autoimmune dis- eases are type-I diabetes mellitus, systemic lupus erythematosus, multiple sclerosis, asthma, psoriasis, glomeru- ...
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