Collecting Duct
Hydrogen ion secretion by the collecting duct as a determinant of the urine to blood PCO2 gradient in alkaline urine
... Several theories have been advanced to explain the elevation in urinary PCO2 during bicarbonate loading and include: (a) H+ secretion, (b) countercurrent system for CO2, (c) the "ampholyte" properties of ...
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Collecting duct–specific knockout of endothelin 1 causes hypertension and sodium retention
... that collecting duct–derived (CD-derived) endothelin-1 (ET-1) can regulate renal Na reabsorption; however, the physiologic role of CD-derived ET-1 is ...
9
Response of the Distal Tubule and Cortical Collecting Duct to Vasopressin in the Rat
... cortical collecting duct including the late segment of the distal tubule, a segment that has also been described by morphologists as the initial collecting ...
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K+ transport in the mesonephric collecting duct system of the toad Bufo bufo
... two collecting duct groups, averaging –70 to −75 mV ...in collecting tubules or collecting ducts, as for example reported by Schlatter and Schafer (1987) for the cortical collecting ...
8
Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice
... The mechanism(s) by which ET-1 deficiency leads to ele- vated adenylyl cyclase levels are unknown. We detected a faint signal for AC5 mRNA and a much stronger signal for AC6. Such findings are in agreement with two ...
6
RETRACTED ARTICLE: Collecting duct carcinoma of the kidney: a clinicopathological study of five cases
... cortical collecting tu- bule, which results in poor prognosis, tumor enucleation and partial nephrectomy are not ...renal collecting duct carcinoma survival ...
5
Developmental plasticity and regenerative capacity in the renal ureteric bud/collecting duct system
... a collecting duct system has been seen as a potential problem of the ...bud/collecting duct system can generate new tips anyway, either at once or as a result of minor treatment, the entire ...
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Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice
... in collecting duct epithelial cells and that Klf5 haploinsufficient mice (Klf5 +/– mice) exhibit ameliorated renal injury in the unilateral ureteral obstruction (UUO) model of tubulointerstitial ...or ...
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Adaptation of rabbit cortical collecting duct HCO3 transport to metabolic acidosis in vitro
... the collecting duct, which has a different dis- tribution and number of intercalated cell types, might respond differently to acid incubation and inhibition of a cell ...
10
Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct
... the collecting duct apical membrane water channel of rat kidney, which is important for the formation of concentrated urine (Fushima, ...of collecting duct (hAQP- CD), that encodes a 271-amino ...
8
Osmolar regulation of endothelin 1 production by rat inner medullary collecting duct
... Recent evidence has implicated endothelin-1 (ET-1) as an autocrine inhibitor of inner medullary collecting duct (IMCD) sodium and water transport. The regulators of IMCD ET-1 production are, however, ...
7
Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice
... renal collecting duct enables regulation of fluid, electrolytes, and acid-base homeostasis, but the molecular mechanism of its development has yet to be eluci- ...renal collecting duct ...
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Mineralocorticoid modulation of apical and basolateral membrane H+/OH /HCO3 transport processes in the rabbit inner stripe of outer medullary collecting duct
... Abstract To examine the mechanism by which mineralocorticoids regulate HCO3- absorption in the rabbit inner stripe of the outer medullary collecting duct, we microfluorometrically measur[r] ...
9
Prostaglandin E2 inhibits renal collecting duct Na+ absorption by activating the EP1 receptor
... PGE2 exerts potent diuretic and natriuretic effects on the kidney. This action is mediated in part by direct inhibition of collecting duct Na+ absorption via a Ca++-coupled mechanism. These studies examine ...
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Expression and distribution of aquaporin of collecting duct are regulated by vasopressin V2 receptor in rat kidney
... of collecting duct (AQP-CD) are regulated by vasopressin V2 receptor (V2R), we performed immunohistochemical studies with specific antibody against ...
7
Apical membrane limits urea permeation across the rat inner medullary collecting duct
... Urea diffuses across the terminal inner medullary collecting duct (IMCD) via a facilitated transport pathway. To examine the mechanism of transcellular urea transport, membrane- apparent urea (Purea) and ...
8
Hormonal regulation of proton secretion in rabbit medullary collecting duct
... With the exception of aldosterone, little is known about the hormonal regulation of distal nephron acidification. These experiments investigated the effects of prostaglandin E2, indomethacin, lysyl-bradykinin, ...
9
Medullary collecting duct acidification Effects of potassium, HCO3 concentration, and pCO2
... The medullary collecting duct (MCD) from renal outer medulla possesses significant HCO3 absorptive capacity. In vitro microperfusion studies have shown that HCO3 absorption in this segment is carbonic ...
9
Effect of collecting duct histology on renal cell cancer outcome.
... Collecting duct renal cell carcinoma (CDRCC) is a rare entity, occurring in less than 2.0% of cases of renal cell carcinoma (RCC). As a result, our knowledge of CDRCC has primarily come from small case ...
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Resistance to hypertension mediated by intercalated cells of the collecting duct
... Precise control of urinary sodium excretion is a critical component of blood pressure regulation. At the molecular level, pathways regulating sodium handling by the kidney affect the reabsorptive functions of renal ...
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