Colon Cancer Stem Cells
Original Article Colon cancer stem cells from HT29 cell line resist to arctigenin via suppressing ROS production
... Abstract: Cancer stem cells (CSCs) are a minority of the tumor cell population with stem cell properties, being con- sidered as the major culprit for tumor initiation, relapse and ...of ...
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Is CD133 a marker of metastatic colon cancer stem cells?
... epithelial cells in adult mouse tissues and on spontaneous primary colon tumors in ...human colon tumors, all of the epithelial cells also expressed CD133, whereas metastatic colon ...
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<p>miR-194 Inhibits the Proliferation of SW620 Colon Cancer Stem Cells Through Downregulation of SSH2 Expression</p>
... in cancer stem cells, controlling the growth and migratory, invasive, and metastatic capacity of ...glioma stem cells isolated from both primary human glioma specimens and a ...
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Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis
... anti- cancer properties in a variety of models, including human studies ...human colon cancer cell lines, however, it was effective only at higher con- centrations (75–100 μM) ...anti-colon ...
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ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs)
... ovarian cancer and melanoma where they appear to play an important role ...CRC cells [14, ...melanoma cells, explaining the different response of these two ...
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Bile acid: a potential inducer of colon cancer stem cells
... of colon carcinogenesis ap- pears to be regulated by the muscarinic cholinergic family of G-protein-coupled receptor, which consists of five sub- types M1R – ...for colon cancer progression [41, ...
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Understanding the colon cancer stem cells and perspectives on treatment
... with cancer chemoresistance; however, increased ATP can activate ABC transporters to increase drug efflux [61] and upregulate HIF-1α signaling, inducing hypoxia-associated drug ...allows cells to tolerate a ...
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Effects of pericytes and colon cancer stem cells in the tumor microenvironment
... In colon cancer, Notch activation in cancer cells by adjacent blood vessel cells increases trans-endothelial migration, and therefore, metastasis ...precursor cells to induce ...
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CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors
... Colon cancer stem cells are believed to originate from a rare population of putative CD133 + intestinal stem ...of colon cancer cells expresses CD133, and that only ...
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CD44variant exon 9 plays an important role in colon cancer initiating cells
... for colon cancer stem ...between cells and the extracellular matrix, cellular motion, and growth/invasion/metastasis of cancer ...in cancer stem cells remains ...
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Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1
... normal colon stem/ progenitor cells in vivo, thus encouraging its potential use for metastatic CRC ...in cancer, we do not exclude it could also be used to successfully treat ...
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Adipose-derived stem cells promote tumor initiation and accelerate tumor growth by interleukin-6 production
... and colon cancer cells. Interaction of ADSCs and cancer cells stimulated secretion of IL-6 in ADSCs, which in turn acted in a paracrine manner on cancer cells to enhance ...
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Isolate and identified cancer stem cells by using MCF7 human breast cancer cell line, using mammospheres formation in two different methods
... of cancer will allow scientists to develop an active target therapy of cancer ...many cells that have the ability to rapidly reproduce many more new cells and increase the ...tumour. ...
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Clusterin , a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis
... during colon cancer progression whose expression is also elevated in intestinal stem cells, we compared patterns of upregulated gene expression that we obtained from L1-overexpressing Ls174T ...
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Effective colon cancer prophylaxis in mice using embryonic stem cells and carbon nanotubes
... staining. Cells were fixed in 2% paraformaldehyde, permeabilized with PermWash buffer (Pharmingen), and incubated with anti-IFN- γ allophycocyanin antibody (BD Biosciences) and anti-TNF-phycoerythrin antibody ...
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Cancer stem cell subsets and their relationships
... precancerous stem cells have the fol- lowing ...instance, colon cancer goes through mild, moderate and severe dysplasia, adenoma, carcinoma in situ, to invasive cancer and metastasis ...
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<p>Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model</p>
... Colon cancer is a common malignant tumor, and its morbidity and mortality are on the rise in recent ...tumor cells but also cause great damage to normal ...tumor cells without harming normal ...
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The role of P63 in cancer, stem cells and cancer stem cells
... basal cells in the breast and prostate, whereas TAp63 isoforms were more widely expressed in these tissues and in tumors at these ...normal colon and in colon ...lymphoid cells and in some ...
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Original Article Down-regulation of lncRNA CCAT1 inhibits colon cancer cell proliferation and promotes apoptosis by targeting apoptosis-related proteins
... Total proteins were prepared from transfect- ed Ishikawa or HEC-1-B cells using radioimmu- noprecipitation assay (RIPA) lysis buffer (Sig- ma, USA) supplemented with protease inhi- bitors. An equal amount (50 μg) ...
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Positive detection of exfoliated colon cancer cells on linear stapler cartridges was associated with depth of tumor invasion and preoperative bowel preparation in colon cancer
... elective colon cancer because of employing “enhanced recovery after surgery” (ERAS) protocol ...colorectal cancer, leading to decrease the possibility of anastomotic recurrence in addition to ...
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