Colon-Specific
NOVEL COLON SPECIFIC DRUG DELIVERY SYSTEM: A REVIEW
... Phosphated cross-linked guar gum was prepared for colon-specific drug delivery. Guar gum cross-linked with increasing amounts of trisodiumtri- metaphosphate to reduce its swelling properties for use as a ...
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SURFACE TENSION BASED MICROCAPSULES AND MICRODISCS FOR COLON SPECIFIC DELIVERY OF SULFASALAZINE
... inflamed colon to provide relief. Often sulfasalazine is targeted in colon to minimize side ...dependent colon targeted system was developed and ...various colon specific polymeric ...
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COLON SPECIFIC DRUG DELIVERY SYSTEM: AN APPROACH TO TARGET COLONIC DISEASES
... for colon- specific drug delivery are usually complex, and the dissolution methods described in the USP cannot fully mimic in-vivo conditions such as those relating to pH, bacterial environment and mixing ...
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Preparation and characterization of azathioprine microspheres for colon specific delivery
... oral colon-specific drug delivery system (CDDS) has been developing as one of the site-specific drug delivery ...of colon following oral administration 1, 2, 3 ...
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Starch film coated microparticles for oral colon specific drug delivery
... ideal colon-specific DDS should effectively suppress the release of active compounds in the stomach and small ...of colon delivery carriers, including the use of bacteria-degradable, pH-sensitive, ...
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DEVELOPMENT OF CHITOSAN CAPSULE FOR COLON SPECIFIC DELIVERY OF BUDESONIDE
... Hence, colon specific delivery of budesonide by using Chitosan capsule was proved to be beneficial in the treatment of Crohn’s ...the colon-specific delivery of budesonide using Chitosan ...
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FORMULATION AND EVALUATION OF SYNTHESIZED QUINAZOLINONE DERIVATIVE FOR COLON SPECIFIC DRUG DELIVERY
... of colon specific delivery is the advantage of 7-chloro-3-(4-chlorophenyl)- 2-phenyl quinazolin-4(3H)-one derivative for colon ...the colon resulting in better patient approval, higher drug ...
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POLYSACCHARIDE MATRIX TABLET FOR COLON SPECIFIC DRUG DELIVERY
... for colon targeting, was selected as the other ...in colon-specific drug delivery as matrix forming material and as a compression coat 12-14 ...
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COLON SPECIFIC DRUG DELIVERY SYSTEMS: CURRENT TRENDS AND APPROACHES
... a colon-specific formulation in various media simulating pH conditions and times likely to be encountered at various locations in the gastrointestinal tract The different media that are used for the ...
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Carbonic anhydrase 1: A study of colon-specific gene regulation
... l colon promoter, notably in the CPI (-78), CP2 (-1 7 9 ) and CP5 (-4 1 7 and -4 7 0 ) ...l colon promoter to repress transcriptional activation in the small ...of colon- specific expression ...
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Different Approaches To Colon Specific Drug Delivery: A Review
... the colon. Pressure controlled colon- delivery capsules of ethylcellulose, were prepared by coating the inner surface of gelatin capsule with ethylcellulose which were insoluble in water ...the ...
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COLON SPECIFIC DRUG DELIVERY SYSTEM: REVIEW ON NOVEL APPROACHES
... of colon targeted drug delivery system. Colon was considered as “BLACK BOX” as, most of drugs are absorbed from upper part of GIT ...the colon would ensure direct treatment at the disease site, ...
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Design and Development of Colon Specific Delivery Systems of Aceclofenac Tablet
... of colon specific drug delivery ...of colon-specific drug delivery systems ...the colon was elucidated much later in 1970 i.e., colon specific azoreductase splits ...
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POLYSACCHARIDE AS A POTENTIAL CARRIER FOR MULTIUNIT COLON SPECIFIC DRUG DELIVERY SYSTEM
... of colon specific drug delivery system have been well recognized and ...of colon related diseases such as ulcerative colitis, colorectal cancer, irritable bowel syndrome and inflammatory bowel ...
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FORMULATION AND EVALUATION OF COLON SPECIFIC MATRIX AND COATED TABLET OF METRONIDAZOLE
... Metronidazole is an ideal drug for formulation as a colon-specific drug delivery. Currently there are a number of sustained release preparations of metronidazole in the market. But that preparation has the ...
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FORMULATION AND EVALUATION OF MICROBIAL TRIGGERED COLON SPECIFIC DELIVERY OF AZATHIOPRINE
... the colon, the use of bacterial degradable polymers for colon specific drug delivery seems to be a more site specific approach as compared to other approaches ...
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FORMULATION AND CHARACTERIZATION OF COLON SPECIFIC DRUG DELIVERY SYSTEM OF A MATRIX TABLET
... develop colon targeted drug delivery system by using Chitosan as a carrier for ...the colon as compare to other matrix tablets containing different ...for colon-specific drug delivery gives ...
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COLON SPECIFIC DELIVERY SYSTEM: THE LOCAL DRUG TARGETING
... transverse colon is ...in colon specific drug delivery are insoluble at low pH levels but become increasingly soluble as pH ...site specific release 14 ...
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A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model
... a colon-specific prodrug of 5-ASA widely used clini- cally) demonstrated that the two prodrugs delivered comparable amounts of 5-ASA to the ...a colon-specific prodrug of ...the colon ...
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STUDIES ON THE DEVELOPMENT AND EVALUATION OF COLON SPECIFIC DRUG DELIVERY SYSTEM CONTAINING MEBEVERINE
... The colon specific drug delivery system (CDDS) should be capable of protecting the drug that entered in the route to the colon ...the colon 3 . The colon is believed to be a suitable ...
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