comparative genomic hybridization analysis
Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridization
... Copy number increase of EFNA1 (1q22), PTGS2 (1q31.1), KDM5B (1q32.1), ESRRG (1q41), KIFC1 (6p21.32), PBX2 (6p21.32) and SOX4 (6p22.3) were only detected in rectal cancer in array CGH. Among them, EFNA1 had increased ...
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Well differentiated angiosarcoma of spleen: a teaching case mimicking hemagioma and cytogenetic analysis with array comparative genomic hybridization
... cytogenetic analysis indicated complex karyotypes, and the specific aberration characteristics for tumor development and behavior have far not been identified ...Cluster analysis of aCGH has identified two ...
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Molecular genetic analysis of cervical cancer using fluorescence in situ hybridization and comparative genomic hybridization
... CGH analysis is extremely dependent on the characteristics of the metaphase ...CGH analysis, all reasonably straight, non-overlapping chromosomes are analysed at each ...
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16p13.3 duplication associated with non-syndromic pierre robin sequence with incomplete penetrance
... chromosomal analysis and subsequently characterized by array-comparative genomic hybridization (array CGH) and confirmed by fluorescence in situ hybridization ...
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Discrepancy of QF-PCR, CMA and karyotyping on a de novo case of mosaic isodicentric Y chromosomes
... (CMA) analysis based on Comparative Genomic Hybridization (aCGH) platform was performed and identified a ...situ hybridization (FISH) revealed a mosaic cell line of 45,X[27]/46,X, ...
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Characterization of Chromosomal Abnormalities in Cancer by Spectral Karyotyping
... The analysis of bands has further advanced into high-resolution chromosome banding ...situ hybridization technique (FISH) enabled detection of chromosomal microdeletions and structural abnormalities ...as ...
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High resolution genomic analysis of sporadic breast cancer using array based comparative genomic hybridization
... our analysis, we reviewed the existing lit- erature on whole genome DNA copy number analysis of human breast cancers; four chromosomal CGH studies [5-8] and two array-based CGH studies [9,10] were used for ...
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Array Comparative Genomic Hybridization as a Diagnostic Tool in Cancer
... Genomic DNA was isolated with QIAamp DNA Mini Kit (51306, Qiagen, Hil- den, Germany) from the above cells and then, aCGH protocol with Sureprint G3 human CGH 8 × 60 K platform (G4450A, Agilent, CA, USA) followed ...
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Porphyromonas gingivalis Strain Diversity
... heteroduplex analysis of the ribosomal operon intergenic spacer region (ISR) to type strains in clinical samples and identified 22 heteroduplex ...sequence analysis to determine the relatedness of ...
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Array-CGH characterization and genotype-phenotype analysis in a patient with a ring chromosome 6
... Array-Comparative Genomic Hybridization (Array-CGH) The array-Comparative Genomic Hybridization (aCGH) study was performed using the Agilent Human Genome CGH Microarray Kit ...
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Genetic analysis of products of conception using a HLPA/SNP-array strategy
... Array-based comparative genomic hybridization; BOBs: BACs-on-Beads; CMA: Chromosomal microarray analysis; CNVs: Copy number variations; FISH: Fluorescence in situ hybridization; HLPA: ...
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Copy number variants in a sample of patients with psychotic disorders: is standard screening relevant for actual clinical practice?
... array comparative genomic hybridization, studies on the putative genetic etiology of schizophrenia have focused on the detection of copy number variants (CNVs), ie, microdeletions and/or ...
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Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature
... One recent microarray technology applied to distin- guish between DLBCL subtypes is array based compara- tive genomic hybridization (aCGH). Array-based CGH provides high resolution genome wide measurement ...
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Monoallelic and biallelic deletions of 13q14 in a group of CLL/SLL patients investigated by CGH Haematological Cancer and SNP array (8x60K)
... with biallelic 13q14 deletion we have detected UPD re- gions. In one patient this neutral copy number LOH covered whole chromosome 13. In the second case small biallelic deletion was located in much bigger UPD re- gion. ...
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Preimplantation genetic screening of blastocysts by multiplex qPCR followed by fresh embryo transfer: validation and verification
... array comparative gen- omic hybridization (CGH), single nucleotide polymorph- ism (SNP) array, quantitative real-time polymerase chain reaction (qPCR), and next generation sequencing (NGS) ...
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Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome
... In general, the patient presented here presents a clin- ical picture that overlaps significantly with the majority of subjects with UPD(14)mat [59], including short stat- ure, small hands and feet, hypotonia, somewhat ...
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Cytogenetics of Leukemias: Identifying Genetic Abnormalities with Clinical and Prognostic Significance
... Cytogenetic analysis helps to confirm the diagnosis of leukemias, and it also aids in obtaining data on prognosis, response to treatment and possibility of ...this analysis and the cells are in active ...
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Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages
... the comparative genomic analysis of ST131 strains and other promi- nent non-ST131 strains (ST38, ST408, and ST648) spanning the extent of extraintestinal pathogenic ...
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MET in glioma: signaling pathways and targeted therapies
... One study searched for genetic alterations in glioblast- omas occurring with or without IDH1 mutations (typical for secondary and primary glioblastoma) using data from The Cancer Genome Atlas (TCGA) and identified 25 ...
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Genome wide array-CGH and qPCR analysis for the identification of genome defects in Williams’ syndrome patients in Saudi Arabia
... WBS is reliably detected by FISH technique, however, no deletions on chromosome 7q could be detected by conventional GTG banding [20]. Although visible deletion could be detected by high resolution tech- nique [21] FISH ...
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