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- Comparative Genomics & Genome Annotation

Genome Annotation and Comparative Genomics of ORF Virus

Genome Annotation and Comparative Genomics of ORF Virus

... The genome of the ORFV is dsDNA of 139,962 bp which has about 89% coding region, 63% GC content and codes 130 ...the genome revealed by homology search of them two posses’ strong regulatory region and ...

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A Comparative Genomics Pipeline for In Silico Characterization and Functional Annotation of Short Hypothetical Proteins

A Comparative Genomics Pipeline for In Silico Characterization and Functional Annotation of Short Hypothetical Proteins

... functional annotation of short hypothetical proteins (only which were < 400 amino acids) comparing two case studies, using amino acid sequence informations retrieved from two different protein ...Our ...

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Computational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insects

Computational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insects

... a genome-sequencing project has proved to be an important step in ensuring the accuracy and reliability of the output into public ...whole genome sequencing to be brought to a close? It is im- portant to ...

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Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae

Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae

... lusitaniae annotation process, we took advantage of available RNA-seq reads obtained from isolates P1, P3, and P4 isolates (see ...reference genome available as a fasta file from PacBio assemblies (see ...

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Comparative Genomics Suggests Primary Homothallism of Pneumocystis Species

Comparative Genomics Suggests Primary Homothallism of Pneumocystis Species

... target genome, which presumably included the genes of inter- ...existing annotation of the genes was considered, and existing collinear coding sequences (CDSs) were retained after assessment using the ...

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Comparative Genomics of Pneumocystis Species Suggests the Absence of Genes for myo Inositol Synthesis and Reliance on Inositol Transport and Metabolism

Comparative Genomics of Pneumocystis Species Suggests the Absence of Genes for myo Inositol Synthesis and Reliance on Inositol Transport and Metabolism

... Pneumocystis Genome Project (PGP, ...the genome, as a comparison for expression of the inositol phosphate metabolism pathway genes, and the Pneumocystis mitochondrial large ribosomal subunit (mtLSU), as a ...

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The Genome of Model Malaria Parasites, and Comparative Genomics

The Genome of Model Malaria Parasites, and Comparative Genomics

... yoelii genome, and by extension, of the other rodent malaria parasite genomes, and their syntenic regions in ...the genome data. For example, creation of a map using partial genome data requires that ...

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Inferring the Minimal Genome of Mesoplasma florum by Comparative Genomics and Transposon Mutagenesis

Inferring the Minimal Genome of Mesoplasma florum by Comparative Genomics and Transposon Mutagenesis

... Genome annotation and phylogenetic ...Every genome was predicted to contain 29 tRNA genes, as well as two rRNA gene loci, each encoding 5S, 16S, and 23S ...

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Comparative Genomics of Escherichia coli Isolated from Skin and Soft Tissue and Other Extraintestinal Infections

Comparative Genomics of Escherichia coli Isolated from Skin and Soft Tissue and Other Extraintestinal Infections

... comparative genomics. Eight of the isolates were sequenced, and comparative genomics analyses were done, including four strains from previous and ongoing studies, providing virulome, ...

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Bioinformatics and Next Generation Sequencing: Applications of Arthropod Genomes

Bioinformatics and Next Generation Sequencing: Applications of Arthropod Genomes

... as genomics, medical diagnosis, biotechnology, virology, biological systematics, forensic biology, and ...on genome assembly, genome annotation, and comparative genomics, using ...

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Genome wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus

Genome wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus

... aureus genome) were identified in ...in genome annotation across multiple strains of ...8325). Genome annotation is typically performed bioinformatically and is rarely validated and ...

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Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure

Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure

... more genome se- quences will generally improve our predictive abilities, our experience shows that propagated errors occur deep into the raw data which render them extremely difficult to ...research, ...

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Comparative genomics of Eucalyptus and Corymbia reveals low rates of genome structural rearrangement

Comparative genomics of Eucalyptus and Corymbia reveals low rates of genome structural rearrangement

... reference genome for eucalypts [29]. Analysis of this genome provided evidence for a whole genome duplication (dated approximately 110 million years ago [MYA]) in eucalypts, which was suggested to ...

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Comparative genomic tools and databases: providing insights into the human genome

Comparative genomic tools and databases: providing insights into the human genome

... For visual comparison of the VISTA and PipMaker outputs, orthologous ApoE genomic sequence from humans and chimpanzees was independently exam- ined by web-based versions of each program (Figure 2, a and b; and Table 1). ...

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Development and Characterization of SSR Markers in Proso Millet Based on Switchgrass Genomics

Development and Characterization of SSR Markers in Proso Millet Based on Switchgrass Genomics

... [17,18]. Comparative genomics has great po- tential to speed up development of genomic tools in mi- nor crops such as proso millet using genome resources of other major crops such as rice, maize, ...

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The genome sequence of the biocontrol fungus Metarhizium anisopliae and comparative genomics of Metarhizium species

The genome sequence of the biocontrol fungus Metarhizium anisopliae and comparative genomics of Metarhizium species

... The comparative genomics of ...published genome analysis of ...acridum genome assembly, which would prevent whole-genome scale synteny from being accurately ...whole genome ...

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Mammalian comparative genomics reveals genetic and epigenetic features associated with genome reshuffling in Rodentia

Mammalian comparative genomics reveals genetic and epigenetic features associated with genome reshuffling in Rodentia

... Sequence coordinates of all mouse genes were obtained from BioMart (RefSeq genes, NCBIm37). Genes were clustered into two groups: (i) total genes, which included protein- coding genes, novel genes with unknown function, ...

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Known unknowns: building an ethics of uncertainty into genomic medicine

Known unknowns: building an ethics of uncertainty into genomic medicine

... whole genome sequencing (and the information they could give rise to) means that results with uncertain significance, uncertain prognostic indicators or a meaning that changes over ...

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Extracting functional trends from whole genome duplication events using comparative genomics

Extracting functional trends from whole genome duplication events using comparative genomics

... A gene duplicability hypothesis has emerged in the scientific literature [15]. Part of this hypothesis centers on the role of gene dosage and interaction, as well as specific attributes of function. Are the same genes ...

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Aldo-keto reductase (AKR) superfamily: Genomics and annotation

Aldo-keto reductase (AKR) superfamily: Genomics and annotation

... identity. Annotation of non-vertebrate AKRs at the National Center for Biotechnology Information or Vertebrate Genome Annotation (vega) database does not often include the systematic nomenclature ...

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