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composite outcome

Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

... the composite in a trial ...the composite outcome may be invalidated or inappropriate for ...the composite outcome, viewing it as meaning- ful, interpretable to represent treatment ...

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The dynamics of response as measured by multiple composite outcome tools in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial

The dynamics of response as measured by multiple composite outcome tools in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial

... Baseline composite scores differed, with the tight control having higher baseline ...the composite measures for the entire population are given in the online supplementary table ...each composite ...

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Validation of a guideline based composite outcome assessment tool for asthma control

Validation of a guideline based composite outcome assessment tool for asthma control

... of composite endpoints is not straightforward when considering a measure that produces a 'state' rather than a ...the composite measures of TC and WC asthma the valida- tion tests have focused on ...

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Development of a composite outcome score for a complex intervention   measuring the impact of Community Health Workers

Development of a composite outcome score for a complex intervention measuring the impact of Community Health Workers

... primary outcome is likely to result in increased statistical power over consid- eration of any one individual screening/immunisation programme ...primary outcome measures distort complex interventions in ...

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Antiretroviral treatment regardless of CD4 count: the universal answer to a contextual question

Antiretroviral treatment regardless of CD4 count: the universal answer to a contextual question

... primary outcome was severe morbidity, a composite outcome that included all- cause deaths, AIDS diseases, and non-AIDS cancers in the three ...primary outcome also included: severe bacterial ...

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Evaluation of hospital outcomes: the relation between length of stay, readmission, and mortality in a large international administrative database

Evaluation of hospital outcomes: the relation between length of stay, readmission, and mortality in a large international administrative database

... a composite outcome measure in which the different combinations of outcomes were or- dered from best to worst outcome: 1) alive, no long LOS, no readmission, 2) alive, long LOS, no readmission, 3) ...

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Neonatal outcomes among multiple births ≤ 32 weeks gestational age: Does mode of conception have an impact? A Cohort Study

Neonatal outcomes among multiple births ≤ 32 weeks gestational age: Does mode of conception have an impact? A Cohort Study

... SC. Composite outcome was defined as combination of death or any of the three neonatal morbidities (grade 3/4 intraventricular hemorrhage or periventricular leukomalacia; retinopathy of prematurity > ...

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Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

... the composite outcome (figure 1A) and all-cause death (figure ...a composite outcome and 2073 ...a composite outcome and 1758 ...

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Follow-up of a Randomized, Placebo-Controlled Trial of Dexamethasone to Decrease the Duration of Ventilator Dependency in Very Low Birth Weight Infants: Neurodevelopmental Outcomes at 4 to 11 Years of Age

Follow-up of a Randomized, Placebo-Controlled Trial of Dexamethasone to Decrease the Duration of Ventilator Dependency in Very Low Birth Weight Infants: Neurodevelopmental Outcomes at 4 to 11 Years of Age

... among controls was ⬎ 70%, a prolonged course of dexa- methasone was used, and no crossover was allowed leads to the conclusion that dexamethasone is associated with significantly reduced odds for mortality (OR: 0.4; 95% ...

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Relationship of Mode of Conception and Sex Concordance With Mortality/Morbidity in Preterm Twins

Relationship of Mode of Conception and Sex Concordance With Mortality/Morbidity in Preterm Twins

... Findings from our analyses are consistent with previous studies reporting no overall difference between ART or SP conception on outcomes in preterm or low-birth-weight twins (Messerschmidt et al., 2010; Schimmel et al., ...

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Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway

Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway

... Results Compared with cephalic births, breech births had substantially increased risk for NNM but not for CP. Vaginal delivery was planned for 7917 of 16 700 fetuses in breech, while 5561 actually delivered vaginally. ...

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Relationships among achieved heart rate, β-blocker dose and long-term outcomes in patients with heart failure with atrial fibrillation

Relationships among achieved heart rate, β-blocker dose and long-term outcomes in patients with heart failure with atrial fibrillation

... established by Fiuzat et al . 10 We plotted unadjusted Kaplan-Meier survival curves strati fi ed by β -blocker and heart rate groups. We then used multivariable-adjusted Cox models to estimate the associations between ...

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Temporal trends in neonatal mortality and morbidity following spontaneous and clinician-initiated preterm birth in Washington State, USA: a population-based study

Temporal trends in neonatal mortality and morbidity following spontaneous and clinician-initiated preterm birth in Washington State, USA: a population-based study

... a composite outcome of neonatal mortality or severe morbidity among preterm ...of composite outcome including neonatal death or severe morbidity among all late preterm ...

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Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis

Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis

... the composite outcome of postoperative complica- tions, while more traditional perioperative risk factors in the medical literature, such as older age and ASA status, were not ...

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Relationship between STarT Back Screening Tool and prognosis for low back pain patients receiving spinal manipulative therapy

Relationship between STarT Back Screening Tool and prognosis for low back pain patients receiving spinal manipulative therapy

... primary outcome (PGIC) at any of the follow up points (Table 4) However, the utility of the SBT to discriminate poor out- come using the PGIC did increase over time, with both medium and high risk groups being ...

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Adults with repaired tetralogy: low mortality but high morbidity up to middle age

Adults with repaired tetralogy: low mortality but high morbidity up to middle age

... A composite end point of ‘serious adverse events’ was prospectively defined as all-cause mortality, heart transplant, documented ventricular arrhythmias and/or heart failure requiring ...

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Meta-analysis of cognitive function in Chinese first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) profile of impairment

Meta-analysis of cognitive function in Chinese first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) profile of impairment

... primary outcome was the overall cogni- tive function (composite score of MCCB); secondary outcomes included the seven MCCB cognitive domains: speed of processing, attention, working memory, verbal learning, ...

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Post renal transplant anemia: severity, causes and their association with graft and patient survival

Post renal transplant anemia: severity, causes and their association with graft and patient survival

... Methods: Patients who underwent kidney transplantation in Rabin Medical Center (RMC) were included in the study. Data were collected during the years 2002 – 2016. Anemia was defined as hemoglobin (Hb) level less than 12 ...

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Nevirapine  versus Efavirenz based antiretroviral therapy regimens in antiretroviral naive patients with HIV and Tuberculosis infections in India: a multi centre study

Nevirapine versus Efavirenz based antiretroviral therapy regimens in antiretroviral naive patients with HIV and Tuberculosis infections in India: a multi centre study

... Ruling out opportunistic infections (OIs) and treating the same, along with early initiation of ART, are the mainstays of HIV management. TB, being the second most common OI in PLHIV [1], causes significant morbidity and ...

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Is competitiveness in the European Union converging?

Is competitiveness in the European Union converging?

... Our choice of approach to national competitiveness draws on the goals specified in the strategy Europe 2020, specifically those of sustainable and inclusive growth. For this reason the approach proposed by Aiginger et ...

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