concanavalin A
Induction of suppressor activity in the autologous mixed lymphocyte reaction and in cultures with concanavalin A
... activity. Concanavalin A (Con A) augments the suppressor activity generated in cultures containing both T and non-T lymphocytes and can induce suppressor activity in T- lymphocyte preparations that contain too few ...
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A T cell dependent experimental liver injury in mice inducible by concanavalin A
... Male NMRI or BALB/c mice developed severe liver injury as assessed by transaminase release within 8 h when an intravenous dose greater than 1.5 mg/kg concanavalin A Con A was given.. His[r] ...
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Variants of Simian Virus 40-Transformed 3T3 Cells That Are Resistant to Concanavalin A
... The variants i resemble 3T3 cells morphologically and in some of their growth characteristics; ii are not agglutinated by high concentrations of concanavalin A or wheat germ agglutinin, [r] ...
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Amelioration of concanavalin A-induced autoimmune hepatitis by magnesium isoglycyrrhizinate through inhibition of CD4<sup>+</sup>CD25<sup>-</sup>CD69<sup>+</sup> subset proliferation
... Abstract: Magnesium isoglycyrrhizinate (MGL) is a new stereoisomer of glycyrrhizic acid, which is clinically used as a hepatoprotective medicine with more potent effects and less side effects than glycyrrhizic acid. This ...
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Studies of Two Subpopulations of Human Lymphocytes Differing in Responsiveness to Concanavalin A
... We have identified two populations of human lymphocytes differing in responsiveness to the plant mitogen concanavalin A (Con-A). When peripheral blood lymphocytes are passed through a nylon column a population of ...
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Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis
... Hepatitis seriously threatens human health and daily life. It is caused by various factors such as viruses, drugs, chemicals, alcohol, genetic factors, or a patient’s own immune system. Currently, effective drugs in the ...
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Concanavalin A induced liver injury triggers hepatocyte proliferation
... Concanavalin A (Con A) injection into mice leads to immune-mediated liver injury. We studied whether after Con A-induced liver injury, TNF- and IL-6-dependent signaling pathways known to be related to hepatocyte ...
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Derangements of liver tissue bioenergetics in Concanavalin A-induced hepatitis
... of concanavalin A-induced hepatitis is dependent on activated immune cells especially NK T cells and the secretion of cytokines, including IFN-γ, and mice in which the cytokine is genetically deleted develop a ...
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Protective effect of galangin in Concanavalin A- induced hepatitis in mice
... Notes: (A) Molecular structure of galangin. (B) c57Bl/6 mice, n=5 per group, received vehicle or galangin (25 or 50 mg/kg) by intraperitoneal injection. Four hours later, galangin injection was repeated. control mice ...
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Concanavalin A inhibits tissue factor coagulant activity
... Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor. Coagulant activity is recovered by addition of alpha-methyl-D-glucoside to inhibited tissue factor. Inclusion of ...
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Location of Ferritin-Labeled Concanavalin A Binding to Influenza Virus and Tumor Cell Surfaces
... The recent finding that most normal and tumor virus-transformed cells have the same number of binding sites for Con-A 2, 8, 29 has led to a hypothesis that a rearrangement of, but not an[r] ...
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Lectin of Concanavalin A as an anti-hepatoma therapeutic agent
... The Con A-induced autophagic cell death with necrosis can initiate a tumor cell-specific immune response, but although Con A can initiate the immune response in a tumor cell in a non-spe[r] ...
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Separation of Herpes Simplex Virus-Induced Antigens by Concanavalin A Affinity Chromatography
... Figure 3B shows the gel diffusion pattern obtained when anti-CP-1 serum was reacted against HSV-SAM, CP-1 antigen, antigen b from infected cells, and the group I fraction obtained from u[r] ...
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Inactivation of Herpes Simplex Virus by Concanavalin A
... HSV-1, McIntyre VR 3 strain, and 1312 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The infectivity of' herpes simplex virus type 1 HSV-1 was inactivated after treatm[r] ...
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Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration
... We have re- cently reported that PF inhibits liver fibrosis induced by dimethylnitrosamine (DMN) in rats [9]. Renal macro- phages, similar to hepatic Kupffer cells, increased signifi- ca[r] ...
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Quantitative Binding of 125I-Concanavalin A to Normal and Transformed Cells
... Although we do not know enough about the actual differences in cell surfaces between transformed and normal cells to distinguish clearly a mechanism for agglutination, we have shown that[r] ...
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Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice
... inflammation and shows strong anti-inflammatory effects. The study reported here investigated whether ghrelin exerted any effect on Con A-induced immune hepatitis and its mechani[r] ...
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Manganese Superoxide Dismutase Therapy in a Murine Hepatitis Associated Injury
... Concanavalin A (Con A) is a lectin protein originally extracted from the jack bean [15]. During the last decade, a model of liver injury by Con A has been widely de- scribed and characterized. Liver injury in this ...
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Original Article Evaluation of glycophenotype in prostatic neoplasm by chemiluminescent assay
... lectins Concanavalin A (ConA), peanut agglutinin (PNA) and Ulex europaeus agglutinin (UEA-I), respectively, specific to α-D- glucose/mannose, Gal-β(1-3)-GalNAc and α-L- fucose, were conjugated to acridinium ester ...
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DNA BARCODING AND BIOLOGICAL ASSESSMENT ON A FEW MANGROVE PLANT SPECIES OF VISAKHAPATNAM COAST, ANDHRA PRADESH, INDIA
... of concanavalin-A is sufficient for the development of liver ...lesions. Concanavalin-A induced hepatitis is both T-cell and macrophage ...to concanavalin-A, a role has been envisaged for these ...
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