Concanavalin-A (Con A)
Induction of suppressor activity in the autologous mixed lymphocyte reaction and in cultures with concanavalin A
... activity. Concanavalin A (Con A) augments the suppressor activity generated in cultures containing both T and non-T lymphocytes and can induce suppressor activity in T- lymphocyte preparations that contain ...
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Amelioration of concanavalin A-induced autoimmune hepatitis by magnesium isoglycyrrhizinate through inhibition of CD4<sup>+</sup>CD25<sup>-</sup>CD69<sup>+</sup> subset proliferation
... against concanavalin A (Con A)-induced autoimmune ...by Con A in C57/6J mice with or without MGL administration; injury score and serum ALT were ...
11
Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis
... clinic. Concanavalin A (Con A) can induce necrosis of hepatocytes; this causes hepatic dysfunction and also attracts and activates immune ...Therefore, Con A is often applied in the animal model of ...
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Studies of Two Subpopulations of Human Lymphocytes Differing in Responsiveness to Concanavalin A
... mitogen concanavalin A ...to Con-A adheres to the fibers while a second population of cells relatively unresponsive to Con-A emerges from the ...
11
Concanavalin A induced liver injury triggers hepatocyte proliferation
... after Con A-induced liver injury, TNF- and IL-6-dependent signaling pathways known to be related to hepatocyte proliferation are ...after Con A injection, maximum TNF-alpha, and after 4-8 h, maximum IL-6 ...
11
Concanavalin A inhibits tissue factor coagulant activity
... of con A with tissue factor preserves coagulant ...that con A interacts reversibly with a carbohydrate residue in such a way as to inhibit coagulant activity of the ...
6
Derangements of liver tissue bioenergetics in Concanavalin A-induced hepatitis
... of concanavalin A-induced hepatitis is dependent on activated immune cells especially NK T cells and the secretion of cytokines, including IFN-γ, and mice in which the cytokine is genetically deleted develop a ...
13
Protective effect of galangin in Concanavalin A- induced hepatitis in mice
... Abstract: Galangin is an active pharmacological ingredient from propolis and Alpinia officinarum Hance, and has been reported to have anti-inflammatory and antioxidative prop- erties. The present study aims to reveal the ...
10
A T cell dependent experimental liver injury in mice inducible by concanavalin A
... revealed leukocyte sticking to endothelial cells and bleb formation of hepatocytes. The hepatotoxicity of the lectin correlated neither with its agglutination activity nor with its sugar specificity. Administration of ...
9
Lectin of Concanavalin A as an anti-hepatoma therapeutic agent
... orally-fed Con A also inhibited liver nodule forma- tion in our system, and this is intriguing because it might open a new field for chemopreventive treatment in ...Natural Con A-like substances that ...
12
Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice
... reduced Con A-induced hepatocellular inflammation and apop- ...reduced Con A-induced elevation of serum ALT and AST levels, as well as levels of the pro-inflammatory cytokines IL-1 β , IL-6, and TNF- α ...
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Modulation of cell-mediated hypersensitivity in experimental allergic encephalomyelitis
... ABBREVIATIONS BSA Bovine serum albumin CFA Complete Freunds Adjuvant CNS Central Nervous System Con A Concanavalin A CSF Cerebrospinal fluid DFO Desferrioxamine DMEM Dulbeccos modified E[r] ...
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Inactivation of Herpes Simplex Virus by Concanavalin A
... HSV-1, McIntyre VR 3 strain, and 1312 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The infectivity of' herpes simplex virus type 1 HSV-1 was inactivated after treatm[r] ...
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Quantitative Binding of 125I-Concanavalin A to Normal and Transformed Cells
... Although we do not know enough about the actual differences in cell surfaces between transformed and normal cells to distinguish clearly a mechanism for agglutination, we have shown that[r] ...
6
Original Article Evaluation of glycophenotype in prostatic neoplasm by chemiluminescent assay
... Here, as reported in these previous works from of our lab, it was observed relationship between the light emitted by the chemiluminescent reaction (RLU) and the tissue area. The nature (linear, hyperbolic and other ...
9
A lectin histochemical study on carbohydrate moieties of the gonadotropin-like substance in the epithelial cells of Hatschek's pit ofBranchiostoma belcheri
... Concanavalin A (Con A), Ulex europaeus agglutinin I (UEA I) and Ricinus corn- munis agglutinin I (RCA l)) indicate that the carbohydrate composition of the gonadotrophic [r] ...
7
Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus
... Normal peripheral blood mononuclear cells demonstrated increased DNA synthesis and secretion of newly synthesized protein when suboptimal concentrations of Concanavalin A (Con A) were added to the cultures ...
12
Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice
... mitogen concanavalin-A (Con A) and anti–CD3 were significantly increased in the mice treated with srmCD40L, suggesting CD40 stimulation also af- fects T cell function ...
9
Mesenchymal stem cells overexpressing IL-35: a novel immunosuppressive strategy and therapeutic target for inducing transplant tolerance
... in concanavalin A (Con A)-induced auto- immune ...with Con A to induce hepatitis, and then they were divided into three groups and intravenously injected with IL-35-MSCs, MSCs, or phosphate-buffered ...
8
Cloning and analysis of the rearranged interleukin-3 gene in the leukaemia cell line WEHI - 3B
... bp base pair CIAP calf intestinal alkaline phosphatase cMGF chicken myelomonocytic growth factor Con A concanavalin A DEAE diethylaminoethyl EDF eosinophil differentiation factor EDTA et[r] ...
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