Congenic strain
Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt resistant rats
... the congenic R strain carrying the S renin gene, BP and plasma renin concentration were lower than in the progenitor Dahl R ...the congenic strain would be ex- pected to increase renin gene ...
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Gene expression profiles of a mouse congenic strain carrying an obesity susceptibility QTL under obesigenic diets
... tabw2 congenic and control mice used in this study were from previously established lines ...the congenic strain at which point two heterozygotes were intercrossed to yield offspring that were either ...
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Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10
... double congenic strain contain some candidate genes that could mediate BP ...of congenic substrains de- rived from the Chr 2 congenic strain (Rapp, ...
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Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat
... progenitor strain and SHR- Lx congenic ...SHR-Lx congenic strain is large, congenic sublines can now be derived for exclusion mapping and for refining the map position(s) of QTLs with ...
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Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
... Idd9 congenic mice pos- sess the potential to transfer disease, demonstrating that the immune system in Idd9 congenic mice is fully capable of mounting a pathogenic anti-islet autoimmune ...Idd9 ...
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Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model
... for strain-specific behavior in the current ...the congenic strain were distinctly up- or downregulated by ATRA in the soleus ...SHR-Lx congenic to result from ...
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Genetic Dissection of X-Linked Interspecific Hybrid Placental Dysplasia in Congenic Mouse Strains
... several congenic laboratory mouse lines (Mus musculus) in which different parts of the maternal X chromosome were derived from ...one congenic strain that retained a ...This strain ...
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Mucosal associated invariant T cell–rich congenic mouse strain allows functional evaluation
... congenic strain that was then crossed to a transgenic Rorcgt-GFP reporter ...hi congenic strain allows phenotypic and functional characterization of naturally occurring mouse MAITs in health ...
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Molecular cloning and duplication of the nematode sex-determining gene tra-1.
... A congenic strain, containing about 5 cM of Bergerac-derived DNA around tra-I, but otherwise isogenic with N2, was constructed by repeated back-crossing (see Mate- r[r] ...
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Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD
... and congenic strains of the same parental ...and congenic placeholder: ...the strain types are first nodes (Figure ...inbred strain which is placed under “inbred” with all substrains under it, ...
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Strain Improvement Studies on T. Thalpophilus strain KS-05
... to strain improvement program with a view to obtain increased amylase ...the strain improvement programme resulted in a mutant that produced ...wild strain (1128 U/ml), which is a significant ...
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The non protein coding breast cancer susceptibility locus Mcs5a acts in a non mammary cell autonomous fashion through the immune system and modulates T cell homeostasis and functions
... In all flow cytometry experiments, cells were stained with fluorophore-conjugated antibodies against rat CD3, CD4, CD8, CD62L, or g δ TCR (BD Biosciences, San Jose, CA, USA) or isotype controls in serum-con- taining ...
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Selection with Recurrent Backcrossing to Develop Congenic Lines for Quantitative Trait Loci Analysis
... If the recurrent line is inbred and the backcrossing and selection is conducted in a series of replicate lines, in each of which only one backcross parent is selected for each generation[r] ...
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Determination of strain deformation statein the meduiim of the initial strain condition
... though strain situation at any one communication area of initial strain viscous-elastic medium depends on the given boundary conditions and boundary form it doesn’t depend on mechanical properties of the ...
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Serious limitations of the QTL/Microarray approach for QTL gene discovery
... By performing three independent congenic microarray experiments, we found high enrichment of genes within donor regions among differentially expressed genes. Within the limits of the donor regions, no clustering ...
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γ-GLUTAMYL CYCLOTRANSFERASE: A NEW GENETIC POLYMORPHISM IN THE MOUSE (MUS MUSCULUS) LINKED TO LYT—2
... Data from genetic crosses, recombinant inbred strains and three congenic strains showed that y-glutamyl cyclotransferase isozymes are under the control of a single gene (Gg[r] ...
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Increased susceptibility to collagen induced arthritis in female mice carrying congenic Cia40/Pregq2fragments
... Cia40 congenic mice and corresponding littermate controls of both sexes were immu- nized with rat CII and monitored three times a week for 90 ...Cia40 congenic mice suffer from an elevated incidence of the ...
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Inheritance of Susceptibility to Friend Mouse Leukemia Virus
... Reciprocal Alteration of Innate Resistance or Susceptibility by Bone Marrow Transplantation Between Congenic Strains Received for publication 2 September 1969 Two newly established mouse[r] ...
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The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice
... two congenic strains heterozygous and homozygous for Idd5 locus by regular SAM analysis, although this had much influence on the severity of ...the congenic mice, although not significantly ...
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Loss of p27Kip1 enhances the transplantation efficiency of hepatocytes transferred into diseased livers
... knockout strain on a 129/Sv × C57BL/6 hybrid background (4), our results, in theo- ry, could be complicated by contributions from other genes that are functionally dif- ferent in the two ...
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