Consequence of AIF-interaction during viral replication
Dynamics of viral replication in blood and lymphoid tissues during SIVmac251 infection of macaques
... in viral load in the peripheral blood and the depletion of central memory CD4+ T cells after two years of SIV ...of viral replication in peripheral cell subsets showed this subpopulation to be highly ...
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Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
... The viral polymerase com- plexes that assembled in the insect cells were purified using an Ni-NTA resin, followed by heparin affinity chromatography, gel filtration, and anion-exchange ...rified viral ...
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Interaction between Geminivirus Replication Protein and the SUMO-Conjugating Enzyme Is Required for Viral Infection
... DNA replication protein PCNA (proliferating cellular nuclear antigen), and the sumoylation enzyme that conjugates SUMO to target proteins (SUMO-conjugating enzyme ...the interaction with SCE1, but no ...
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The interaction of hepatitis B virus with the ubiquitin proteasome system in viral replication and associated pathogenesis
... body: During hepatitis B virus (HBV) infection, the UPS is shown to act as a double-edged sword in viral ...the viral life cycle and induces their ubiquitin-dependent proteasomal degradation to limit ...
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Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication
... FIG 1 Application of I-DIRT to identify mLANA-binding proteins in lytic MHV68 infection. (A) Overview of the I-DIRT method. Light or heavy isotopically labeled 3T3 fibroblasts were infected with either recombinant MHV68 ...
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Nuclear IE2 Structures Are Related to Viral DNA Replication Sites during Baculovirus Infection
... parental viral genomes show the tendency, initially described for HSV-1 genomes, to associate with the periphery of PML domains ...initiating viral DNA replication ...incoming viral genomes ...
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Interaction of the Human Papillomavirus E1 Helicase with UAF1 USP1 Promotes Unidirectional Theta Replication of Viral Genomes
... E1-UAF1 interaction during the initial replicative amplification of the HPV11 ...of viral replication intermediates (RIs) generated by the unidirectional mechanism more severely than those ...
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ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication
... activation during active HIV replica- tion ...expression during the HIV infection of Jurkat cells, we evaluated whether the interaction of these proteins with PKR reflected these ...inhibited ...
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Heterogeneous Nuclear Ribonucleoprotein A2 Participates in the Replication of Japanese Encephalitis Virus through an Interaction with Viral Proteins and RNA
... specific interaction between the JEV core protein and hnRNP ...of viral RNA replication in cells infected with JEV, and the reduction was cancelled by the expression of an siRNA-resistant hnRNP A2 ...
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Interaction of JC Virus Agno Protein with T Antigen Modulates Transcription and Replication of the Viral Genome in Glial Cells
... and replication of the viral genome in glial ...the viral late gene promoter and T-antigen-induced replication of viral ...antigen interaction in the observed down-modulation of ...
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Replication of Avian Sarcoma Virus In Vivo Requires an Interaction between the Viral RNA and the TψC Loop of the tRNATrp Primer
... includes during cloning, when each vector library is ligated and propagated in bacteria; during transfection of TEFs with the vector libraries; and during infection of TEFs with the virus ...
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HMGB1 Promotes Hepatitis C Virus Replication by Interaction with Stem-Loop 4 in the Viral 5′ Untranslated Region
... In this study, we investigated HMGB1 functions in HCV rep- lication and translation. We found that the level of HCV RNA and protein was significantly increased or reduced when we conducted HMGB1 overexpression or ...
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Viral Replication. Viral Replication: Basic Concepts
... Schematic of Replication Cycle of (+) RNA Single Strand Viruses Coding for. Genomic and Subgenomic RNA’s Genomic RNA binds to ribosomes but only a portion of 5’ end is translated into [r] ...
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Structural and biochemical insights of CypA and AIF interaction
... Some CypA regions suggested by our data as potential sites of recognition for AIF, do not fit with this model. However, additional contacts have been suggested by the docking computational solutions, like the one ...
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Cellular Compartmentalization of Herpesvirus Antigens During Viral Replication
... viously (7), labeled Ra-BIC antibody reacts with viral antigens localized in nuclei of infected cells, i.e., the nuclear granules and the amorphous mass.. The pool of human 'y-globulin c[r] ...
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The role of a viral microRNA and RNA interference during viral replication in mammalian cells
... viruses during natural infection in ...suggest viral miRNAs might make worthy anti-viral drug ...identifying viral-encoded miRNAs that does not require an experimental infectious ...
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Cellular and Viral Factors Regulate the Varicella-Zoster Virus gE Promoter during Viral Replication
... for viral replication and is involved in cell-to- cell spread, secondary envelopment, and ...of viral and cellular transcriptional factors in regulation of the gE ...VZV replication ...
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AIF Downregulation and Its Interaction with STK3 in Renal Cell Carcinoma
... Moreover, AIF is a free radical scavenger that prevents apoptosis induced by reactive oxygen species ...of AIF on cell death may be cell type-specific. For example, AIF gene silencing protects renal ...
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Interaction of Epstein-Barr virus nuclear antigen 1 with the viral latent origin of replication.
... To determine how the binding of EBNA-1 to sites in region II leads to the initiation of DNA synthesis and to investigate the role of region I, EBNA-1 has been overproduced in insect cell[r] ...
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Analysis of the interaction of viral RNA replication proteins by using the yeast two-hybrid assay.
... to viral positive-strand RNA replication has not been ...the interaction between and among the BMV viral ...the interaction between the helicase-like region of 1a and the N terminus of ...
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