Contextual fear conditioning
Temporary inhibition of dorsal or ventral hippocampus by muscimol: distinct effects on measures of innate anxiety on the elevated plus maze, but similar disruption of contextual fear conditioning
... of contextual fear by dorsal hippocampal muscimol (Esclassan et ...of contextual, but not tone, fear conditioning by hippocampal muscimol resembles the selective anterograde deficits in ...
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Dopamine D1 like receptor signalling in the hippocampus and amygdala modulates the acquisition of contextual fear conditioning
... the conditioning context and another separate context after learning, suggesting that they show generalization of con- textual ...on contextual fear generalization, although this could be ...
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Intraperitoneal sertraline and fluvoxamine increase contextual fear conditioning but are without effect on overshadowing between cues
... examined contextual condi- tioned freezing rather than discrete cue conditioning procedures (Inoue et ...of contextual conditioned fear assessed in freezing procedures (Inoue et ...the ...
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Impaired learning and memory in CD38 null mutant mice
... the contextual fear conditioning task, which is another hippocampus- dependent memory task ...a conditioning chamber where mild foot shocks were ...same conditioning chamber and their ...
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Effects of D amino acid oxidase inhibition on memory performance and long term potentiation in vivo
... neuronal and behavioral effects are influenced by DAAO inhibition remain elu- sive. In anesthetized rats, extracellular field excitatory postsynaptic potentials (fEPSPs) were recorded before and after a theta frequency ...
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Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
... in contextual fear conditioning (CFC) which is a hippocampus- dependent associative learning and memory task [28– ...profound contextual fear memory deficit at 24 h after training ...
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Antidepressant like effects of a water soluble extract from the culture medium of Ganoderma lucidum mycelia in rats
... MAK was provided by Noda Shokukin-kogyo Co. Ltd. (Noda, Japan). The preparation of MAK (overall yield, ≈ 10%) was as follows: a pure culture of G. lucidum mycelia was inoculated into a solid culture medium that was ...
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The Regulation of Gene Expression During Memory Consolidation in the Hippocampus
... Long-term contextual memories are formed in the hippocampus of the rodent through a process involving distinct stages of acquisition, consolidation, maintenance and retrieval ...[2]. Contextual fear ...
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Genes and signaling pathways involved in memory enhancement in mutant mice
... recognition, contextual fear conditioning, context discrimination, and the Mor- ris water maze ...and contextual fear conditioning, which are hippocampus- dependent tasks ...
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Prior observation of fear learning enhances subsequent self-experienced fear learning with an overlapping neuronal ensemble in the dorsal hippocampus
... Contextual fear conditioning and subsequent testing were performed in a triangular conditioning chamber (length of sides: 15 cm, 18 cm, 23 cm; height: 27 cm) that had a stainless-steel grid ...
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α2 adrenoceptor mediated inhibition in the central amygdala blocks fear conditioning
... Contextual Fear conditioning. Subjects. Subjects were 32 experimentally naïve, male, Sprague-Dawley rats (weighting between 320 g to 400 g). Rats were obtained from a commercial supplier (Animal ...
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Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females
... or fear renewal. This is the return of learned fear after extinction when the CS is presented outside of the extinction context and evidence indicates that fear renewal activates PL and hippocampus ...
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Effects of dopamine D1 modulation of the anterior cingulate cortex in a fear conditioning procedure
... of contextual fear conditioning as has previously been demonstrated in nucleus accumbens (Albrechet-Souza et ...study contextual fear conditioning was increased by treatment with ...
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Preclinical Models of Overwhelming Sepsis Implicate the Neural System that Encodes Contextual Fear Memory
... impaired contextual fear conditioning has emerged as a robust phenotype in post-septic animals (21,41–45, but see ...the contextual as- pects of emotional ...in contextual emotional ...
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Propranolol–induced Impairment of Contextual Fear Memory Reconsolidation in Rats: A Similar Effect on Weak and Strong Recent and Remote Memories
... impairs fear memory ...auditory fear conditioning (Dębiec & LeDoux, 2004), contextual fear conditioning (Abrari, Rashidy-Pour, Semnanian, & Fathollahi, 2008; Mu- ravieva ...
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Hippocampal function is not required for the precision of remote place memory
... a contextual fear conditioning paradigm, which is an associative learning between a place and aversive experience, some studies demonstrated that the hippocampus is always necessary for the precision ...
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Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory
... The hippocampus plays a crucial role in contextual fear conditioning and consolidation of this memory [46, 52–54]. To understand the role of calpain in memory formation, we investigated whether ...
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Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory
... hippocampus-dependent contextual fear ...of contextual fear memory. However, the extinction of contextual fear memory was not ...to contextual fear memory, they may ...
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PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory
... Background: Memory consolidation, reconsolidation, and extinction have been shown to require new gene expression. Poly ADP-ribosylation mediated by poly (ADP-ribose) polymerase-1 (PARP-1) is known to regulate ...
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Analyses of fear memory in Arc/Arg3 1 deficient mice: intact short term memory and impaired long term and remote memory
... of fear memory in ...impaired fear memory in both contextual and cued test ...a conditioning trial, their performance was impaired in the retention test after 24 hr or longer, either with or ...
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