COPD Exacerbations
Thiazolidinediones are associated with a reduced risk of COPD exacerbations
... of COPD severity, including previous COPD exacerbations and prescriptions for respiratory medications, but it was unclear whether fewer base- line exacerbations and respiratory medications ...
7
Optimizing bronchodilation in the prevention of COPD exacerbations
... in exacerbations between IND/GLY (110/50 μg ...all COPD exacerbations (RR ...severe exacerbations (RR ...of exacerbations in patients with a history of ≥2 exacer- bations in the ...
24
The causes and consequences of seasonal variation in COPD exacerbations
... The seasonality of COPD exacerbations is an important feature of COPD, and the mechanisms responsible are complex and interrelated. More research is always needed, but a fruitful area would be an ...
10
Colds as predictors of the onset and severity of COPD exacerbations
... between exacerbations coinciding with colds and those occurring when colds were absent was estimated by a generalized estimating equation (GEE) ...of COPD exacerbations and colds was further ...
10
Th17 profile in COPD exacerbations
... Abstract: COPD is characterized by an ongoing inflammatory process of the airways that leads to obstruction or limitation of ...of COPD, the most important are neutrophils, macrophages and CD4+ and CD8+ T ...
9
Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo – a post-hoc analysis of the BACE randomized controlled trial
... We recently reported the results of the Belgian trial with Azithromycin for acute COPD Exacerbations requiring hospitalization (BACE, NCT02135354) [7]. The BACE trial was an investigator-initiated ...
12
Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients
... for COPD exacerbations was significantly higher in the hospital sample compared to the population sample, even after extensive adjustment for potential ...
10
COPD exacerbations by disease severity in England
... of COPD-related admissions in the first group indicate that although patients in GOLD B incur fewer exacerbations compared to GOLD C, these are likely to be more severe and lead to hospital ...that ...
13
Treatment of COPD exacerbations: antibiotics
... In the first study conducted by the current author, Treatment of Acute exaCerbaTions of chronIC bronchitis (TACTIC) [43], the quinolone antibiotic moxifloxacin 400 mg o.d. for 5 days was compared with the ...
7
Optimizing antibiotic selection in treating COPD exacerbations
... in exacerbations of ...for exacerbations, antibiotic treatment was only prescribed if the procalcitonin level was above a certain ...with exacerbations, where the majority of exacerbations are ...
14
Pulmonary biomarkers in COPD exacerbations: a systematic review
... Pulmonary biomarkers sampled during stable COPD have been assessed for their potential to predict an imminent ECOPD and to identify patients at risk for fre- quent ECOPD (Table 3). Some molecules, such as FeNO ...
12
Observational study of the outcomes and costs of initiating maintenance therapies in patients with moderate exacerbations of COPD
... of COPD exacerbations, COPD-related costs, and maintenance treatment rates during the 1-year period after the index ...date. COPD exacerbations were defined as a COPD-related ...
8
Exacerbations of COPD
... While COPD is a mainly chronic disease, a substantial number of patients suffer from ...Severe exacerbations are related to a significantly worse survival ...severe exacerbations should be treated ...
9
The comparative effectiveness of initiating fluticasone/salmeterol combination therapy via pMDI versus DPI in reducing exacerbations and treatment escalation in COPD: a UK database study
... moderate/severe COPD exacerbations and long-acting muscarinic antagonist (LAMA) prescriptions, for COPD patients initiating fluticasone propionate (FP)/salmeterol xinafoate (SAL) via pMDI versus DPI ...
10
Variability of antibiotic prescribing in patients with chronic obstructive pulmonary disease exacerbations: a cohort study
... for COPD patients being administered in this ...with exacerbations or the effect of prescribing antibiotics on this utilisation ...acute COPD exacerbations ...acute exacerbations ...
8
Improving Interprofessional and Coproductive Outcomes of Care for Patients with Chronic Obstructive Pulmonary Disease
... acute COPD exacerbations is nearly ...for COPD exceed $35 billion. 3 Up to 40% of patients with COPD exacerbations do not receive guideline-directed therapies, and up to 50% receive at ...
8
Observational study on the impact of initiating tiotropium alone versus tiotropium with fluticasone propionate/salmeterol combination therapy on outcomes and costs in chronic obstructive pulmonary disease
... COPD exacerbations are associated with significant risk of persistent disability and death, incur substantial economic and clinical burdens in terms of healthcare resource use and costs, and are a major ...
9
Use of a care bundle in the emergency department for acute exacerbations of chronic obstructive pulmonary disease: a feasibility study
... with COPD exacerbations following the introduction of a COPD bundle, it is difficult to be certain that the bundle alone was responsible for ...of COPD following the demonstration of indices ...
7
Exacerbations in the pre- and post-COPD diagnosis periods
... the COPD diagnosis, this same group of individuals experienced a range of 0 to 28 respiratory ...probable COPD exacerbations the mean (SD) was ...probable COPD exacerbations was lower ...
6
Elevated serum of ECP in acute exacerbations of COPD
... mortality. Exacerbations of COPD are a major cause of morbidity, mortality and hospital ...During COPD exacerbations, airway inflammation shows some features of Eosinophilic inflammatory ...
6