cortical collecting duct
Electrical properties of the rabbit cortical collecting duct from obstructed and contralateral kidneys after unilateral ureteral obstruction
... Abbreviations used in this paper: CCD, cortical collecting duct; CD cell, collecting duct cell; control, sham operation; DOCA, deoxycorticosterone acetate; ZXEMF, change in basolateral m[r] ...
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Effects of uninephrectomy on electrical properties of the cortical collecting duct from rabbit remnant kidneys
... the collecting duct cell in the isolated cortical collecting duct (CCD) from rabbits 14 d after uninephrectomy (UNX); results were compared with those from sham-operated rabbits ...
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Mechanism of enhanced Na K ATPase activity in cortical collecting duct from rats with nephrotic syndrome
... The maximal hydrolytic activity of Na-K-ATPase is specifically increased in the cortical collecting duct (CCD) of rats with puromycin-induced nephrotic syndrome (NS). This stimulation is independent ...
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Response of the Distal Tubule and Cortical Collecting Duct to Vasopressin in the Rat
... the cortical collecting ...the cortical collecting duct including the late segment of the distal tubule, a segment that has also been described by morphologists as the initial ...
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Transcriptional activation of RACTK1 K+ channel gene by apical alkalization in renal cortical collecting duct cells
... of renal collecting tubule cells. To determine whether extra- cellular pH induces the RACTK1 gene expression in the re- nal cortical collecting duct (CCD) cells, we measured mRNA of the RACTK1 ...
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Endothelium derived relaxing factor inhibits transport and increases cGMP content in cultured mouse cortical collecting duct cells
... Stimulation of the release of endothelium-derived relaxing factor (EDRF) in the kidney has been shown to result in natriuresis without affecting glomerular filtration rate. This may be due to EDRF directly regulating ...
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Prostaglandin E2 inhibits sodium transport in rabbit cortical collecting duct by increasing intracellular calcium
... The mechanism by which prostaglandin E2 (PGE2) inhibits sodium absorption (JNa) in the rabbit cortical collecting duct (CCD) was explored. PGE2 activates at least three signaling mechanisms in the ...
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Expression of GTPase deficient Ras inhibits vasopressin signaling in cultured cortical collecting duct cells
... Cross-talk between signaling pathways is increasingly recognized as integral to cellular function. We investigated whether the mitogen-activated protein kinase (MAPK) pathway alters vasopressin (AVP) stimulation of ...
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Effects of vasopressin and bradykinin on anion transport by the rat cortical collecting duct Evidence for an electroneutral sodium chloride transport pathway
... in cortical collecting ducts isolated from rat kidneys have shown that vasopressin increases both sodium absorption and potassium secretion, while bradykinin inhibits sodium absorption without affecting ...
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Electrical properties of the rabbit cortical collecting duct from obstructed kidneys after unilateral ureteral obstruction Effects of renal decapsulation
... the cortical collecting duct ...the collecting duct cell, were inhibited in the obstructed kidney after unilateral ureteral obstruction ...
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Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct
... enzymatically to their respective diols, vic-dihydroxyeicosatrienoic acids (DHETs). We studied the effect of pretreatment with DHETs on 10 microU/cm2 arginine vasopressin (AVP)-stimulated hydraulic conductivity (Lp) (Lp ...
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Cyclic adenosine monophosphate stimulated anion transport in rabbit cortical collecting duct Kinetics, stoichiometry, and conductive pathways
... Cyclic AMP stimulates HCO3 secretion and Cl self-exchange in rabbit cortical collecting tubule. We found that varying peritubular [Cl] changed the Cl self-exchange rate with saturation kinetics (Km, 3-4 ...
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Short term effects of uninephrectomy on electrical properties of the cortical collecting duct from rabbit remnant kidneys
... We conclude: a the initial effect of UNX 3 h in the collecting duct cell is an increase in apical membrane Na+ conductance; b the delayed effects of UNX 6 and 24 h are increases in apica[r] ...
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Inhibition of amiloride sensitive apical Na+ conductance by acetylcholine in rabbit cortical collecting duct perfused in vitro
... the collecting duct cells accompanied by a positive deflection of VT and an increase in transepithelial resistance, whereas it did not affect these parameters in the beta-intercalated ...
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Control of sodium and potassium transport in the cortical collecting duct of the rat Effects of bradykinin, vasopressin, and deoxycorticosterone
... absorption and potassium secretion in cortical collecting ducts perfused in vitro. Arginine vasopressin causes a reversible increase in net potassium secretion and net sodium absorption. Bradykinin in the ...
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Adaptation of rabbit cortical collecting duct HCO3 transport to metabolic acidosis in vitro
... lactate and 6 l -alanine, pH 7.4, 290 6 2 mosmol / kg (13, 17). CCDs were isolated by freehand dissection from the medullary rays of the midcortex using fine forceps under a stereomicroscope. The midcorti- cal tubules ...
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Functional characterization of three intercalated cell subtypes in the rabbit outer cortical collecting duct
... The distribution of Na+-independent Cl--HCO3- exchange was studied in individual intercalated cells from in vitro perfused rabbit outer CCDs using dual excitation laser scanning confocal[r] ...
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Luminal vasopressin modulates transport in the rabbit cortical collecting duct
... However, because the principal cell is thought to participate, if not exclusively, in AVP-regulated water transport in the CCD 26, 35, the inhibition of the hydroosmotic effect of basola[r] ...
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Effect of isoproterenol on intracellular pH of the intercalated cells in the rabbit cortical collecting ducts
... Abstract To examine the mechanisms which regulate the functions ofthe intercalated cells ICs in the cortical collecting duct CCD, the effect of isoproterenol on intracellular pH pHi of I[r] ...
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Differential expression of mRNA for guanylyl cyclase linked endothelium derived relaxing factor receptor subunits in rat kidney
... the cortical collecting duct contained mRNA only for alpha 1 and beta 2 ...and cortical collecting duct, suggesting that several different EDRF receptors exist in ...
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