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Cough reflex

Bradykinin sensitizes the cough reflex via a B2 receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

Bradykinin sensitizes the cough reflex via a B2 receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

... of cough that BK, microinjected into the nTS, enhanced the cough reflex but did not affect respiratory parameters ...the cough response. For example, several studies investigating central ...

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Detection of airway protective level of the cough reflex in acute stroke patients

Detection of airway protective level of the cough reflex in acute stroke patients

... [1]. Cough reflex plays a very important role in airway protection, the site of aspiration into the lung is the larynx, there are two main types of laryngeal mechanism that prevent aspiration: those that ...

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Evaluation of antitussive activity of Lycopus europaeus on cough reflex induced by different cough induced models in mice

Evaluation of antitussive activity of Lycopus europaeus on cough reflex induced by different cough induced models in mice

... painful cough. Cough suppressants act to reduce the urge to ...in cough. These putative cough receptors have myelinated afferents and are found mainly in the larynx and the extrapulmonary ...

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Anti-Tussive Activity of Oldenlandia Umbellata on Cough Reflex Induced by Sulfur Dioxide in Mice

Anti-Tussive Activity of Oldenlandia Umbellata on Cough Reflex Induced by Sulfur Dioxide in Mice

... a cough model induced by sulfur dioxide gas in ...of cough reflex at 3 hours after drug administration and the anti-tussive activity was comparable to that of codeine phosphate, a standard ...

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Anatomy and neuro-pathophysiology of the cough reflex arc

Anatomy and neuro-pathophysiology of the cough reflex arc

... Since cough is an important defensive reflex, required to maintain the health of the lungs, people who do not cough effectively are at risk of atelectasis, recurrent pneumonia, and chronic airways ...

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A physiological model of the human cough reflex: investigations of the afferent pathway and antitussive studies

A physiological model of the human cough reflex: investigations of the afferent pathway and antitussive studies

... Lack of effect of codeine in the treatment of cough associated with acute upper respiratory tract infection.. Codeine and its alternatives for pain and cough relief.[r] ...

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Role of Autonomic Nervous System and the Cough Reflex in the Increased Responsiveness of Airways in Patients with Obstructive Airway Disease

Role of Autonomic Nervous System and the Cough Reflex in the Increased Responsiveness of Airways in Patients with Obstructive Airway Disease

... of cough receptors results in bronchoconstriction through efferent cholinergic ...sensitized cough receptors may be involved in triggering reflex airway constriction in such ...

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Assessment and modulation of the sensorimotor cough response

Assessment and modulation of the sensorimotor cough response

... The cough reflex test (CRT) challenges the integrity of the sensorimotor cough response by introducing a tussive agent to the respiratory tract via inhalation, and observing for a cough ...

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Effects of aural stimulation with capsaicin ointment on swallowing function in elderly patients with non-obstructive dysphagia

Effects of aural stimulation with capsaicin ointment on swallowing function in elderly patients with non-obstructive dysphagia

... induce cough reflex, which has been shown to prevent aspiration pneumonia, aural stimulation with capsaicin may reduce the incidence of aspiration pneumonia in dysphagia patients via Arnold’s ...

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ANTITUSSIVE MEDICINAL HERBS - AN UPDATE REVIEW

ANTITUSSIVE MEDICINAL HERBS - AN UPDATE REVIEW

... the cough reflex (number of cough efforts, cough frequency, intensity of the maximal cough effort and intensity of the coughing attack during inspiration and during expiration) were ...

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Proton pump inhibitor responsive chronic cough without acid reflux: a case report

Proton pump inhibitor responsive chronic cough without acid reflux: a case report

... Recent studies have indicated that PPIs have effects well beyond acid suppression, and have revealed many types of inflammatory cytokines in the esophageal mucosa of GERD patients [8]. Hamaguchi et al. [9] showed that ...

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A novel reflex cough testing device

A novel reflex cough testing device

... stimulates cough receptors in the vestibule of the larynx and initiates the laryngeal cough reflex [3, 6, ...a cough re- sponse was elicited or the subject failed to respond within 30 s after ...

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Changes in terminology and management of over-the-counter cough therapy – time for a fresh perspective?

Changes in terminology and management of over-the-counter cough therapy – time for a fresh perspective?

... receptors are located in the middle ear, diaphragm, pleura and stomach, the external auditory canals, eardrums, paranasal sinuses, pharynx, diaphragm, pleura and pericardium. These receptors include rapidly-adapting ...

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XII AIST 2018 Conference: “The thousand faces of cough: clinical and therapeutic updates”

XII AIST 2018 Conference: “The thousand faces of cough: clinical and therapeutic updates”

... chronic cough (often referred to as idiopathic, unexplained or cough hypersensitivity syndrome) is a condition when cough persists despite the treatment of associated co-morbid conditions such as ...

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Bradykinin as a Probable Aspect in SARS-Cov-2 Scenarios: Is Bradykinin Sneaking out of Our Sight?

Bradykinin as a Probable Aspect in SARS-Cov-2 Scenarios: Is Bradykinin Sneaking out of Our Sight?

... Bradykinin as a potent vasodilator autacoid peptide is widely distributed in plasma and different tissues. It is produced via enzymatic activity of kallikrein on the low molecular weight and high molecular weight ...

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The Objective Assessment of Cough Frequency in Bronchiectasis

The Objective Assessment of Cough Frequency in Bronchiectasis

... of cough. We did not assess patients for potential causes of cough, such as laryngeal and sinus disease, gastro-oesophageal reflux and ...influenced cough frequency since it is associated with ...

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CLINICAL EFFICACY AND SAFETY OF KOFAREST DROPS IN PRODUCTIVE COUGH

CLINICAL EFFICACY AND SAFETY OF KOFAREST DROPS IN PRODUCTIVE COUGH

... A cough is usually a sudden, involuntary, expulsion of air from the lungs with a characteristic and easily recognizable ...The cough reflex is characterized by complexicity and plasticity that is ...

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Cough Modulation by Upper Airway  Stimuli in Cat—Potential Clinical Application?

Cough Modulation by Upper Airway Stimuli in Cat—Potential Clinical Application?

... the cough motor pattern (Figure ...within cough E1 phase was able to temporarily interrupt the active expiratory phase (Figure 3), but it did not change EMG amplitude or phase durations ...reduced ...

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The efficacy of QingfengGanke granule in treating postinfectious cough in pathogenic wind invading lungs syndrome: a multicenter, randomized, double-blind, placebo-controlled trial

The efficacy of QingfengGanke granule in treating postinfectious cough in pathogenic wind invading lungs syndrome: a multicenter, randomized, double-blind, placebo-controlled trial

... persistent cough triggered by URTI and lasting for 3–8 weeks [8, ...of cough [14], pathogenic wind invading lungs syndrome was diagnosed in the presence of cough, throat itchiness, cough ...

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Whooping Cough

Whooping Cough

... A BSTRACT : Pertussis or whooping cough is a highly contagious infection of the respiratory tract caused by the bacterium albordtella pertussis. It’s a disease that could affects human at all his stages of life ...

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