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CSF, colony-stimulating factor

Human granulocyte colony stimulating factor (hG-CSF): cloning, overexpression, purification and characterization

Human granulocyte colony stimulating factor (hG-CSF): cloning, overexpression, purification and characterization

... Biopharmaceuticals are medicinal products comprising biotechnology-derived recombinant proteins as active substances, according to the European Agency for the Evaluation of Medicinal Products [1]. Biopharmaceuticals have ...

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Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis

Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis

... Randomized allocation sequence was adequately gen- erated in six trials [41-43,46-48], for the other six trials it was judged to be unclear based on the available docu- ments [37-40,44,45]. Allocation sequences ...

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Small Molecules that Mimic or Antagonize Actions of Granulocyte Colony- Stimulating Factor (G-CSF)

Small Molecules that Mimic or Antagonize Actions of Granulocyte Colony- Stimulating Factor (G-CSF)

... In order to identify a mode of action for the Kusano compounds (Cmpds#1-3), a limited computational analysis was performed. In brief, the coordinates for G-CSF bound to its receptor were obtained from the NCBI ...

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Pichia pastoris versus Saccharomyces cerevisiae: a case study on the recombinant production of human granulocyte macrophage colony stimulating factor

Pichia pastoris versus Saccharomyces cerevisiae: a case study on the recombinant production of human granulocyte macrophage colony stimulating factor

... Expression of rhGM‑CSF in P. pastoris and S. cerevisiae Recombinant P. pastoris and S. cerevisiae rhGM-CSF clones were expressed as described previously [9, 10]. The expression of the rhGM-CSF was ...

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Effect of Combination Therapy Using Hypothermia and Granulocyte Colony-Stimulating Factor in a Rat Transient Middle Cerebral Artery Occlusion Model

Effect of Combination Therapy Using Hypothermia and Granulocyte Colony-Stimulating Factor in a Rat Transient Middle Cerebral Artery Occlusion Model

... A previous study reported that G-CSF treatment in aged rats led to a reduced mortality, an improved functional recovery of motor function [10]. In addition to enhanced recovery of post stroke motor and cognitive ...

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Clinical use of plerixafor in combination with granulocyte-colony stimulating factor in hematopoietic stem cell transplantation

Clinical use of plerixafor in combination with granulocyte-colony stimulating factor in hematopoietic stem cell transplantation

... A phase II multicenter pilot study trial consisting of 26 MM and 14 NHL patients addressed the issue of whether plerixafor can boost the PBSC mobilization associated with chemotherapy and G-CSF. The design ...

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Recombinant Granulocyte Colony-Stimulating Factor Administered Enterally to Neonates Is Not Absorbed

Recombinant Granulocyte Colony-Stimulating Factor Administered Enterally to Neonates Is Not Absorbed

... Granulocyte colony-stimulating factor (G-CSF) is present in liquids swallowed by the fetus and neonate; specifically, amniotic fluid, colostrum, and hu- man ...as stimulating neutrophil ...

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Activities of stromal and immune cells in HPV-related cancers

Activities of stromal and immune cells in HPV-related cancers

... Granulocyte-macrophage colony- stimulating factor; HGF: Hepatocyte growth factor; HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; HNSCC: Head and neck squamous cell ...

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Increased granulocyte colony stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony stimulating factor receptor mutation derived from a patient with severe congenital neutropenia

Increased granulocyte colony stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony stimulating factor receptor mutation derived from a patient with severe congenital neutropenia

... appear to be unique to SCN as they have not yet been re- ported in other neutropenic syndromes (0 of 18 tested) or in healthy subjects (0 of 30 tested) (10, 26, 27). These mutations all result in the generation of a ...

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Intravenous Administration of Granulocyte-Colony Stimulating Factor for Stem Cells Mobilization and Third Degree Burn Wound Healing in Rats

Intravenous Administration of Granulocyte-Colony Stimulating Factor for Stem Cells Mobilization and Third Degree Burn Wound Healing in Rats

... The increasing importance of cell therapy in burn wound healing and the necessity of developing a safe and effective therapeutic method, has attracted the attention of researchers for designing an alternative strategy to ...

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The Effect of stem cell mobilisation with granulocyte colony-stimulating factor on the morphology of the haematopoietic organs in mice

The Effect of stem cell mobilisation with granulocyte colony-stimulating factor on the morphology of the haematopoietic organs in mice

... The foetal liver of mice is a major site of embry- onic blood cell production from, approximately, embryonic day 12 to birth [36]. In adults the liver is an auxiliary organ where between 10% and 15% of the total pool of ...

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RESEARCH ARTICLE Granulocyte-colony stimulating factor in neonatal sepsis with leukopenia: A prospective cohort study

RESEARCH ARTICLE Granulocyte-colony stimulating factor in neonatal sepsis with leukopenia: A prospective cohort study

... Conclusions: The mean duration for recovery from leukopenia with G-CSF treatment in neonatal sepsis was less than 2 days and had no significant relationship with pre-GCSF absolute neutrophil count. The ...

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In vitro and in vivo activation of endothelial cells by colony stimulating factors

In vitro and in vivo activation of endothelial cells by colony stimulating factors

... granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage-colony-stimulating factor (GM-CSF), and to compare them with those elicited by prototypic ...

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Osteoclasts; culprits in inflammatory osteolysis

Osteoclasts; culprits in inflammatory osteolysis

... granulocyte/macrophage colony-stimulating factor [67] and vascular endothelial growth factor [68], which compensate for the absence of ...

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Host microenvironment in breast cancer development Inflammatory and immune cells in tumour angiogenesis and arteriogenesis

Host microenvironment in breast cancer development Inflammatory and immune cells in tumour angiogenesis and arteriogenesis

... important factor responsible for increased macrophage infiltration in breast cancer is the macrophage colony-stimulating factor (CSF)-1; this is a haematopoietic growth factor ...

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Granulocyte macrophage colony stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes

Granulocyte macrophage colony stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes

... Granulocyte-macrophage colony-stimulating factor (GM-CSF) is known as an inducer of proliferation and functional activation of myeloid ...necrosis factor-alpha (TNF-alpha); ...

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A randomized study comparing chemotherapy followed by G-CSF alone or in combination with GM-CSF for mobilization of peripheral blood stem cells in patients with non-Hodgkin’s lymphomas

A randomized study comparing chemotherapy followed by G-CSF alone or in combination with GM-CSF for mobilization of peripheral blood stem cells in patients with non-Hodgkin’s lymphomas

... Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) are the two most commonly used cytokines for ...

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A Randomized Trial of Granulocyte-Macrophage Colony-Stimulating Factor in Neonates With Sepsis and Neutropenia

A Randomized Trial of Granulocyte-Macrophage Colony-Stimulating Factor in Neonates With Sepsis and Neutropenia

... adequate renal and liver function, and had documented serum creatinine levels ⱕ2.0 mg/dL and serum glutamic-pyruvic transaminase ⱕ 3 times normal. Exclusion criteria were the pres- ence of major congenital anomaly or ...

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Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system

Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system

... growth factor; G-CSF: Granulocyte colony-stimulating factor; GM-CSF: Granulocyte macrophage colony- stimulating factor; Ig: Immunoglobulin; INF: Interferon; ...

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A screen for peptide agonists of the G CSF receptor

A screen for peptide agonists of the G CSF receptor

... Granulocyte-colony stimulating factor (G-CSF) is one the most widely employed protein ...G- CSF can reduce the infarct size in animal stroke models [9-11] and that it has significant ...

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