Cutaneous lupus
Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
... Results: Accumulation of TNFa protein in conditioned medium containing PBMCs from DLE patients, but not from SCLE, TLE or DM patients, was significantly greater (19-fold) than that from controls (P < 0.001). In DLE ...
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<p>A review of cutaneous lupus erythematosus: improving outcomes with a multidisciplinary approach</p>
... and cutaneous lupus with the fi nding that low levels are not ...of cutaneous lupus as measured by a clinical scoring system called the Cutaneous Lupus ...
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Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus
... Fifteen consecutive patients with refractory CLE were included. The major subtypes of the recruits were discoid lupus erythematosus (DLE) (60%), lupus profundus (13%) and subacute cutaneous ...
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Validity and sensitivity to change of laser Doppler imaging as a novel objective outcome measure for cutaneous lupus erythematosus.
... localised cutaneous lupus disease area and severity index, LDI: Laser Doppler imaging, PSAC: physician subjective assessment of change, PU: perfusion unit, VAS: visual analogue scale ...
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Inflammatory and T Helper 17/ Regulatory T Cells Related Cytokines Balance in Cutaneous Lupus Erythematosus (CLE)
... study, IL-17/IL-10 ratio was greater in patients with malar rash compared to other patients and normal controls and IL-23/IL-10 ratios were higher in patients with SLE and CLE compared to normal individuals. Therefore, ...
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Original Article Apoptosis in chronic cutaneous lupus erythematosus, discoid lupus, and lupus profundus
... Introduction: Lupus erythematosus is a multisystemic disease that is characterized by autoantibody production and immune complex deposition in such tissues as the mucosa, joints, the central nervous system, and ...
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Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti Ro (SSA) autoantibodies into human skin grafted mice
... Subacute cutaneous lupus and neonatal lupus are closely associated with the presence of anti-Ro (SSA) autoantibodies, but there is no direct evidence establishing a role for anti-Ro (SSA) in these ...
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Fas ligand promotes an inducible TLR dependent model of cutaneous lupus–like inflammation
... the lupus subtype by clini- cal presentation, either acute cutaneous lupus (ACLE), subacute cutaneous lupus (SCLE), or chronic cutaneous lupus ...human lupus ...
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Pathophysiology of cutaneous lupus erythematosus
... chronic cutaneous lupus erythematosus, such as DLE, while showing some effect in ACLE and SCLE ...chronic cutaneous lupus erythe- matosus responded to B cell-depleting therapy, with some ...
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Toxic Epidermal Necrolysis-Like Cutaneous Lupus in Pediatric Patients: A Case Series and Review
... systemic lupus erythematosus (SLE) is difficult as the differential diagnosis is broad and includes drug reactions such as toxic- epidermal necrolysis (TEN)/Stevens- Johnson syndrome (SJS), bullous SLE, Rowell ...
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Study on Clinicopathological Spectrum of Cutaneous Lupus Erythematosus and Its Correlation with Ancillary Tests
... This is to certify that dissertation entitled “ A STUDY ON CLINICOPATHOLOGICAL SPECTRUM OF CUTANEOUS LUPUS ERYTHEMATOSUS AND ITS CORRELATION WITH ANCILLARY TESTS’’ is a record of bonafide work done by ...
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Applicability of the Cutaneous Lupus Erythematous disease Area and Severity Index (CLASI) in patients with Systemic Lupus Erythematosus (SLE)
... Cutaneous lupus erythematosus disease area and severity index (CLASI) is a relatively new tool formulated in 2005 by American dermatologists at the Veterans Affairs Hospital, Philadelphia, ...of ...
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Subacute Cutaneous Lupus Erythematosus in Older Man: Case Report
... Systemic lupus erythematosus (SLE) is an autoimmune disease that affects mainly women, presents several clinical manifestations and has no known ex- act ...taneous lupus erythematosus (SCLE) being one of ...
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Update on the use of topical calcineurin inhibitors in cutaneous lupus erythematosus
... Abstract: Cutaneous manifestations of lupus erythematosus (CLE) are manifold, presenting with unspecific skin manifestations or well-defined clinical dermatological ...systemic lupus erythematosus is ...
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Human histocompatibility antigen associations in subacute cutaneous lupus erythematosus
... subacute cutaneous LE of either type and an even greater relative risk ...subacute cutaneous LE can now be added to the growing list of HLA-B8, DR3-associated diseases that ...
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Topical calcineurin inhibitors in systemic lupus erythematosus
... diseases. Cutaneous lupus erythematosus (CLE) is a broad term which includes a variety of lesions which may appear without the systemic manifestations of systemic lupus erythematosus ...contrast, ...
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Thalidomide Responsiveness in an Infant With Behçet's Syndrome
... arthritis, cutaneous lupus erythematosus, inflammatory bowel disease, and most recently, has been used to treat the aphthous ulceration seen in human immunodeficiency virus- associated ...
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Systemic Lupus Erythematosus (SLE)
... Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus ...acute cutaneous lupus, chronic cutaneous lupus, oral ulcers, nonscarring ...
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A short overview on systemic drug induced lupus erythematosus
... Drug-induced lupus erythematosus (DILE) arises after exposure to certain drugs for a period of time that induces a lupus like syndrome, which resolves after the offending drugs are ...idiopathic ...
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Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature
... systemic lupus erythematous (SLE) ...refractory cutaneous lupus (non SLE), suggesting that targeting the TH-17 pathway may be useful in this condition, its use in SLE remains poorly described ...
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