Cxcl1/Cxcl2
Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains
... Since the source of the HS preparation appeared to determine its inhibitory activity, compe- tition assays were performed using isolated endothelial glycocalyx, HS from bovine kidney or the highly sulfated enoxaparin. ...
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<p>Candidate Gene Analysis Of Alopecia Areata In Jordanian Population Of Arab Descent: A Case–Control Study</p>
... Background: Alopecia areata (AA) is a non-cicatricial patchy hair loss on the scalp, face or other parts of the body. AA was found to be responsive to immunosuppressive therapies, a fi nding that supports an autoimmune ...
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TNF α Promotes Nuclear Enrichment of TonEBP/NFAT5 to Selectively Control Inflammatory but not Osmoregulatory Responses in Nucleus Pulposus Cells
... of CXCL2 and ...of CXCL1, CXCL2, and CXCL3, which were significantly decreased in TonEBP-knockdown NP cells ...the CXCL1 promoter via a highly conserved NF-κ B binding site To investigate ...
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RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo developmental competence in PCOS patients
... ADAMTS9, CXCL1, CXCL2, CXCL3, and ITGB5) were targeted from our previous cDNA microarray data which isolated genes related to oocyte nuclear maturation in PCOS ...
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CCR2 Deficiency Promotes Exacerbated Chronic Erosive Neutrophil-Dominated Chikungunya Virus Arthritis
... CXCL1, CXCL2, G-CSF, and IL-1  levels were increased in arthritic feet of CCR2 ⫺/⫺ mice, whereas IL-10 levels were de- creased, suggesting that multiple mediators were involved in pro- moting neutrophil ...
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NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG
... CCL5, CXCL1, and CXCL2, to over 2 μg/mL for ...and CXCL1 production at levels exceeding tenfold ...and CXCL1, while SN50 and NBP only weakly inhibited production of any of the four fac- ...of ...
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CXCL1 CXCR2 axis mediates neutrophils recruitment in rat oral mucosa
... of CXCL1 and CXCL2 production ...of CXCL1-CXCR2 axis in neutrophils recruitment, we further testify whether CXCL1-CXCR2 axis is FK506’s target on neutrophils ...both CXCL1 and CXCR2 ...
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<p>ELR positive CXCL chemokines are highly expressed in an animal model of ulcerative colitis</p>
... of CXCL1-4, CXCL6- 7, CXCL13, and CXCL16 chemokines were increased, the expressions of CXCL9, CXCL10, CXCL11, CXCL12, and CXCL17 chemokines had no change, and the expression of CXCL14 was decreased compared to the ...
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Vol 69, No 1 (2017)
... A well-known characteristic of TRPV1 function- ing is that its response can be sensitized or desen- sitized. Sensitization, mainly due to increased phos- phorylation by PKC or PKA [33,34], is associated with higher or ...
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MicroRNA 223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment
... was Cxcl2, a chemokine involved in PMN chemotaxis ...(Cxcl2, Cxcl1, Il6, Ccl2, and Ccl3) (Figure 5B and Supplemental Figure ...of CXCL2, CCL3, and IL-6 were sig- nificantly increased in lung ...
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An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE
... EAE. CXCL1 is released by choroid plexus epithelium in the early stages of both cEAE and aEAE, and promotes neutrophil migration into the fourth ven- tricle and meningeal ...a CXCL2 concentration gradi- ...
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PubMedCentral-PMC5334284.pdf
... (B) CXCL1 (KC) and (C) CXCL2 (inflammatory protein 2-alpha, MIP-2α), of pro-fibrotic markers (D) transforming growth factor (TGF) β1, (E) TGFβ3 and (F) connective tissue growth factor (CTGF) as well as ...
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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow
... endothelial cells and osteoblasts constitutively expressed the ELR + chemokines CXCL1 and CXCL2, and CXCL2 expression was induced in endothelial cells during G-CSF– induced neutrophil mobilization. ...
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TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis
... study, CXCL1 (KC) was the most highly upregulated gene by microarray analysis in the retinas of eyes infected with ...of CXCL1. Elevated CXCL1 expression was not surprising, considering its ...
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Chemokine (C-C Motif) Receptor 1 Is Required for Efficient Recruitment of Neutrophils during Respiratory Infection with Modified Vaccinia Virus Ankara
... Ccl5, Cxcl1, and Cxcl2 by MVA and constitutive expression of Ccl9 ...or Cxcl2 in primary MLFs and trig- gered only a slight upregulation of ...
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Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a
... (IHC). CXCL1 expressed in both the epithelial and stromal components of the HCC ...stroma, CXCL1 was expression was diffuse. In tumor cells, CXCL1 expression was mainly localized to the cytoplasm ...
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On the inflammatory response in metal on metal implants
... In patients with metallosis gene expression of cytokines, particularly of CXCL2 and CXCL10, was higher compared to patients with aseptic loosening of a total joint replace- ment. Due to the small number of ...
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The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts
... of CXCL1 or IL8 in human colon cancer cells promotes tumorigenicity and are upregulated in human ulcerative colitis and colon cancer [18, ...elevated CXCL1 mRNA expression in human occurs throughout the ...
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Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells
... Our data clearly demonstrate that both the immortalized BEAS-2B cell line and primary NHBE cells are activated by C. neoformans. Using either cell source, acapsular C. neofor- mans grown at 37°C elicited the maximal ...
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Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis
... Concerning CXCL2, which is extremely chemotactic for neutrophils [20], an upregulated expression of mRNA and protein in inflamed gut, predominantly in UC has been shown ...
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