Cytokine gene polymorphisms
Cytokine gene polymorphisms and their clinical relevance
... the cytokine gene polymorphisms were calculated by direct counting and then dividing by the number of subjects to produce genotype frequency, or by the number of chromosomes to produce allele ...
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Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms
... genetic polymorphisms to this ...months. Cytokine gene polymorphisms were determined in both mothers and ...γ gene, rs3181032, was found to be associated with child ’ s IFN- γ levels at ...
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Association of Proinflammatory Cytokine Gene Polymorphisms With Susceptibility to Otitis Media
... of cytokine gene polymorphisms in OM susceptibility, Joki-Erkella et al 28 studied TNF- ␣ ⫺308 , IL-1 ␣ ⫺889 , IL-1  ⫺511 , IL-1  ⫹3953 , and IL-1 receptor antagonist genes in 20 OM-susceptible ...
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This study was planned for testing the association of cytokine gene polymorphisms with susceptibility and clinical types of leprosy among Egyptian cases
... of cytokine gene polymorphisms with the susceptibility and clinical severity of leprosy among Egyptian cases from the Nile ...IL-1Ra polymorphisms may influence development of leprosy in the ...
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Association of cytokine gene polymorphisms with hepatitis C virus infection in a population from Rio de Janeiro, Brazil
... Cytokine gene polymorphisms are strongly associated with ...between cytokine polymorphisms and HCV infection because it is a highly genetically diverse population, composed primarily of ...
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The effect of cytokine gene polymorphisms on renal transplantation and atherosclerosis
... affect gene expression and function, and therefore phenotype - encompassing variations within the promoter regions, exons and introns as well as the surrounding ...the polymorphisms was followed by attempts ...
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Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)
... We were able to confirm our previously reported, novel finding of an association between IL6 genotype and atopic phenotypes by observing elevated IgE concentra- tions among G/G genotypes. Contrary to our findings from ...
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Inflammation-related cytokine gene polymorphisms in Behçet’s disease
... These results might have prognostic value for future clini- cal observations. Further, TNF- α ( - 308) polymorphism may serve as a guideline in determining the response to anti-TNF- α therapy, as patients with GG ...
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Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study
... for polymorphisms in cytokine genes affecting the risk of CKD is ...No cytokine genes were identified as susceptibility loci for CKD in a Cauca- sian population in a genome-wide association study ...
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Interaction between cytokine gene polymorphisms and the effect of physical exercise on clinical and inflammatory parameters in older women: study protocol for a randomized controlled trial
... of cytokine production and physical performance in the older adult, but also to the response of these variables to physical ...single cytokine geno- type without considering its interaction with other ...
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Human Leukocyte Antigen and Cytokine Receptor Gene Polymorphisms Associated With Heterogeneous Immune Responses to Mumps Viral Vaccine
... of cytokine genes can affect multiple aspects of cytokine biology, such as transcriptional activity, protein produc- tion, receptor binding, direct interactions with viral pro- teins, and functional ...
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IRF5 gene polymorphisms in melanoma
... As a theoretical limitation of this study, we refrained from genotyping the melanoma metastases with the as- sumption that polymorphisms of the germline were suf- ficiently representative. Due to the genetic ...
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DVWA gene polymorphisms and osteoarthritis
... Summing up, DVWA gene was recently related to OA through a genome wide association study in the Japanese population. Today, a very limited number of reports have clarified its molecular role on cartilage ...
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Gene Polymorphisms Associated with Atrial Fibrillation
... MYZAP gene polymorphisms A polygenic process involving transcription factors, cardiac ion channels, myocardial and cytoskeletal proteins plays an important role in AF ...cytoskeletal gene PLEC, are ...
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Identification of Rabbit Myostatin Gene Polymorphisms
... The existence of selection on the rabbits with potential for meat has only been seen from phe- notypic aspects including performance and productivity, while the molecular genetic studies are still very rare. One of the ...
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Apolipoprotein E gene polymorphisms and migraine
... ApoE: 51 patients (75%) [1] and 47 (67%) [2] had an E3/E3 genotype; 11 (16%) [1] and 11 (16%) [2] had a E3/E4 genotype; 5 (7%) [1] and 7 (10%) [2] had a E2/E3 genotype; 1 (1%) [1] and 5 (7%) [2] had a E4/E4 genotype; 2 ...
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Association of CCR2 Gene but not CCR5 Gene Polymorphisms with Alzheimer’s Disease
... related polymorphisms in a number of autoimmune and infectious ...CCR5 gene mutations with Late-onset Alzheimer’s disease (LOAD) and the relation between clinical features and genotypes in affected ...two ...
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Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed race population with Crohn’s disease
... Conclusion In conclusion, this study has shown that TGFB1 polymor- phisms may be associated with susceptibility to CD, while IL10 polymorphisms may influence CD phenotypes. Thus, the polymorphic sites of both ...
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Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs
... compared with controls. However, TNF α serum levels correlated negatively with the use of antimalarial treatment during at least three months before sampling. Patients under single or combined treatment with these drugs ...
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Association between IL-18/18R gene polymorphisms and coronary artery disease: influence of IL-18/18R genetic variants on cytokine expression
... Discussion This research revealed that the G allele from the rs1169288 carriers is associated with CAD onset. This study’s find- ings are similar to those of Morita et al 11 who reported a significant association between ...
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