cytokine-induced killer cell
Efficacy of cytokine-induced killer cell infusion as an adjuvant immunotherapy for hepatocellular carcinoma: a systematic review and meta-analysis
... of cytokine-induced killer (CIK) cell-based immunotherapy as an adjuvant therapy for hepatocellular carcinoma ...keywords: cytokine-induced killer cell, ...
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Original Article Inhibition of autophagy in cytokine-induced killer cell promotes its cytotoxicity
... activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL) had potent in vitro cytotoxici- ty against susceptible tumor cells and har- nessed established tumors in animal ...cer. ...
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Original Article Efficacy analysis of triple-negative breast cancer patients treated with dendritic cell-cytokine-induced killer cell immunotherapy
... dendritic cell-cytokine-induced killer (DC-CIK) cell immunotherapy combine with chemotherapy with or without radiotherapy for triple-negative breast cancer (TNBC) patients following ...
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<p>Autologous Cytokine-Induced Killer Cell Immunotherapy for Patients with High-Risk Diffuse Large B Cell Lymphoma After the First Complete Remission</p>
... cancer. Cytokine-induced killer (CIK) cells, a heterogeneous immune cell population induced by speci fi c stimulation (such as rhIFN-a, rhIL-2, and anti-CD3 monoclonal antibody) of ...
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Autologous cytokine-induced killer cell transfusion increases overall survival in advanced pancreatic cancer
... T cell transfer. Cytokine-induced killer (CIK) cells are a heterogeneous subset of T lymphocytes ex- panded ex vivo that express CD3 and CD56 as well as natural killer group 2, member D ...
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Targeting prostate cancer stem-like cells by an immunotherapeutic platform based on immunogenic peptide-sensitized dendritic cells-cytokine-induced killer cells
... hematopoietic cell medium (Lonza X-VIVO™ 15 ...dendritic cell (DC) cul- ture and the suspended PBLs were collected for cytokine-induced killer cell (CIK) ...DC-CIK cell ...
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The prognostic value of peripheral CD4 CD25 T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cells-cytokine induced killer cells infusion
... Since there were increasingly evidences that cancers included immunogenetic or non-immunogenetic types, we were not able to discriminate the types for those BC patients. The T cell infiltration in tumor ...
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Original Article Efficacy of autologous tumor antigen sensitized dendritic cells in combination with cytokine induced killer cells on ovarian cancer immune therapy
... natural killer cells that mainly reflects the nonspecific immune response ...Ag-DC-CIK cell infusion, whereas the control group received CIK cell ...with cytokine induced CIK immuno- ...
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Effect of dendritic cell cytokine induced killer cells in patients with advanced colorectal cancer combined with first line treatment
... recent cell-based therapeutic ...before cell transfusion can enhance anti-tumor effects in previous clinical studies ...T cell activation during cell therapies ...
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Evaluation of tumor response to cytokine induced killer cells therapy in malignant solid tumors
... CIK cells therapy has been evaluated as an adoptive cell immunotherapy for cancer patients in a number of clinical trials [13,17-26]. In our department, CIK cells therapy has been applied on more than 4000 cancer ...
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FOLFOX regimen plus dendritic cells–cytokine-induced killer cells immunotherapy for the treatment of colorectal cancer: a meta-analysis
... Data were extracted by two researchers independently (Yan Liu and Zhong Zheng), and discrepancy was resolved upon discussing with a third researcher (Qixin Zhang). Extracted information included first author’s names, ...
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In vitro influence of mycophenolate mofetil (MMF) and Ciclosporin A (CsA) on cytokine induced killer (CIK) cell immunotherapy
... Regarding cytokine/chemokine secretion, we observed no significant differences between CIK cells with and without MPA treatment expect for a significant reduction in TNFα ...CIK cell therapy with CsA ...
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Long-term survival of a patient with recurrent gallbladder carcinoma, treated with chemotherapy, immunotherapy, and surgery: a case report
... T cell transfer among patients with intra- hepatic bile duct cancer ...DC-activated, cytokine-induced killer cells enhanced the anti-tumor effects of chemotherapy in patients with ad- vanced ...
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Chemotherapy combined with dendritic cell vaccine and cytokine-induced killer cells in the treatment of colorectal carcinoma: a meta-analysis
... Patients and methods: PubMed, Embase, and Cochrane Library databases were searched systematically for clinical trials of DC vaccine and CIK cell therapy combined with chemotherapy for CRC. The primary and ...
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Cytokine-induced killer (CIK) cells: from basic research to clinical translation
... Compared with unrelated donor peripheral blood and bone marrow, umbilical cord blood (UCB) has several ad- vantages, including easy acquisition, rapid availability, and low to no risk of adverse events such as GVHD [57]. ...
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<p>Application Of Adoptive Immunotherapy In Ovarian Cancer</p>
... CIK cell therapy in patients with hematologic ...CIK cell therapy following fi rst-line treatment in advanced ...CIK cell maintenance immunotherapy can help improve overall sur- vival, but CIK ...
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Cytokine-Induced Killer Cells as an Adoptive Cellular Immunotherapy Strategy for Hepatocellular Carcinoma
... T cell receptor signaling or IL-10, and transforming growth factor-β-mediated suppression, cause a scene of immune tolerance to tumors ...natural killer (NK) cells ...T cell stimulation, activate ...
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Cellular immunotherapy as maintenance therapy prolongs the survival of the patients with small cell lung cancer
... CIK: Cytokine-induced killer; CIT: Cellular immunotherapy; CR: Complete remission; CT: Computed tomography; CSCs: Cancer stem cells; CTL: Cytotoxic T lymphocyte; CTLA-4: Cytotoxic T-lymphocyte ...
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Clinical applications of dendritic cells–cytokine-induced killer cells mediated immunotherapy for pancreatic cancer: an up-to-date meta-analysis
... Literature screening and data extraction were carried out by two independent reviewers (YZ and XZ), and disagreements were eliminated upon discussing with a third researcher (AZ). Extracted information included first ...
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Efficacy and safety of cord blood-derived dendritic cells plus cytokine-induced killer cells combined with chemotherapy in the treatment of patients with advanced gastric cancer: a randomized Phase II study
... CB-DC-CIK could be infused in patients at the end of the culture period. CB-DC-CIK can induce gastric cancer cell death in vitro and produce high levels of cytokines such as IFN- γ , TNF- α , and IL-2, which can ...
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