cytoplasmic domain
Fusion Activity of Transmembrane and Cytoplasmic Domain Chimeras of the Influenza Virus Glycoprotein Hemagglutinin
... of cytoplasmic water- soluble molecules as ...and cytoplasmic domain sequences nor any particular length of its ...membrane-spanning domain is ...and/or cytoplasmic amino acid sequences ...
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The Cytoplasmic Domain of Marburg Virus GP Modulates Early Steps of Viral Infection
... the presence of its cytoplasmic domain. (A) Schematic representation of MARV GP deletion mutant. Filoviral glycoproteins are composed of the N-terminal ectodomain (ED), the hydrophobic membrane-span- ning ...
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The cytoplasmic domain of chondrolectin interacts with the β-subunit of rab geranylgeranyl transferase
... chodl cytoplasmic domain from the chodl cDNA construct (pUA855) with the primers 5’-gtcgacggggaggaggaggaggaggaacctgctgtttccagatgttg and 5’-gcggccgctatacctccatgccactttcc in a PCR program of: 94ºC for 5 min, ...
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Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein.
... Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain i[r] ...
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Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain
... a cytoplasmic domain ...plasmic domain–deleted mice are viable and exhibit no spontaneous ...the cytoplasmic domain but is due to a low level of hTF expression that is below a threshold ...
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The Tale of the Long Tail: the Cytoplasmic Domain of HIV-1 gp41
... One of the most enigmatic phenomena regarding gp41CD is its cell-type-dependent requirement for HIV-1 replication. Trunca- tion of gp41CD blocks replication of HIV-1 in most cell types, including peripheral-blood ...
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Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins.
... To investigate the role of the gp41 cytoplasmic domain in virus replication, the effect of deletions in this region on the synthesis, processing, cell surface expression, incorporation i[r] ...
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The cytoplasmic domain of simian immunodeficiency virus transmembrane protein modulates infectivity.
... We investigated the function of the SIVmac envelope cytoplasmic domain by replacing the in-frame stop codon by 4395 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A st[r] ...
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Differences in the role of the cytoplasmic domain of human parainfluenza virus fusion proteins.
... the cytoplasmic domain of the vesicular stomatitis virus G protein reduced or eliminated its transport to the cell surface ...HN cytoplasmic tail deletion mutant was found at the cell surface in ...
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Cytoplasmic Domain Signal Sequences That Mediate Transport of Varicella-Zoster Virus gB from the Endoplasmic Reticulum to the Golgi
... gB cytoplasmic domain between aa 818 and 826 is required for the efficient transport of gB from the ER to the Golgi, whereas the sequences immediately ad- jacent to this region do not contribute ...
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Conformational analysis of a receptor cytoplasmic domain
... UV CD spectra were obtained of the peptide in various media in order to ascertain the range of states available to the domain. The results could be classified into three broad sections viz. those in which the CD ...
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Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1
... (A) C2C12 myoblasts were transfected with wild-type (WT) and the C-terminal inhibitory domain mutant STIM1 and labeled with anti-STIM1 antibody, phalloidin, and 4’,6-diamidino-2-phenylindole (DAPI). WT STIM1 ...
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Modification of the Cytoplasmic Domain of Influenza Virus Hemagglutinin Affects Enlargement of the Fusion Pore
... the cytoplasmic tail pro- mote pore dilation? Based on the observation that GPI-an- chored HA causes the formation of a metastable hemifusion diaphragm after triggering the conformational change of the ectodomain ...
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Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein alters the conformation of the external domain.
... These results show that the truncation of the The truncated and full-length TM proteins are not detected cytoplasmic tail markedly increases the ability to detect the on cell surfaces by[r] ...
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Reassessment of the capacity of the HIV 1 Env cytoplasmic domain to trigger NF κB activation
... Given that T lymphocyte activation is a prerequisite to HIV replication and that the viral promoter LTR con- tains NF-κB binding sites, identifying the factors that do promote viral transcription and induce apoptosis in ...
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Signal transduction by the Fat cytoplasmic domain
... Functionally important sequence motifs can often be identified by evolutionary conservation. Mammals have four Fat genes, which share a similar extracellular domain (ECD) structure with Drosophila Fat and Kugelei ...
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The Cytoplasmic Tail Domain of Epstein Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment
... gB cytoplasmic domain “clamp” and enable gB activation, respec- tively (21, ...the cytoplasmic domains of gB and gH might function together in regulating cell fusion ...gH cytoplasmic tail CTD ...
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Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin-beta receptor modulates the signal pathway of the lymphotoxin-beta receptor.
... transmembrane domain and therefore displays ab- normal migration ...interaction domain of the HCV pro- tein with LT-bR lies in its N-terminal 40-amino-acid ...cytoplasmic domain. Since, sim- ...
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Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA
... T5-encoded tapasin does not associate with TAP In order to confirm that the truncated tapasin did not associate with TAP due to the absence of a transmem- brane and cytoplasmic domain, we looked for the ...
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Ubiquitylation and Developmental Regulation of Invariant Surface Protein Expression in Trypanosomes
... ATPase domain of BiP (BiPN) containing the signal sequence (SS) (residues 1 to 415) is fused to an HA epitope, followed by the ectodomain, TMD, and cytoplasmic domain of ...
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