Cytoskeletal dynamics
Continuum descriptions of cytoskeletal dynamics
... study cytoskeletal dynamics, while keeping track of each individual cytos- keletal filament, of each motor molecule, and of any other cytoskeletal protein possibly present, for example, the passive ...
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Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
... Metabolic reprogramming is an important driver of tumor progression; however, the metabolic regulators of tumor cell motility and metastasis are not understood. Here, we show that tumors maintain energy production under ...
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Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure
... In order to test whether there was an underlying causality to the correlation between actin-myosin activity and the macroscopic cell shape fluctuations, we modified cytoskeletal dynamics exclusively in the ...
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Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance
... anticapping proteins, (6) sever F-actin, (7) bundle, cross- The dynamic instability of microtubules was first di- link, or otherwise stabilize F-actin, and (8) anchor F-actin rectly observed in vivo in fibroblasts ...
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Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics
... actomyosin dynamics and apical ...actin dynamics and the localization of the actin remodeling protein cofilin ...the cytoskeletal dynamics that promote apical constriction and identify cofilin ...
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Thrombocytopenia associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets
... cytoskeletal dynamics. We next used immunofluorescence to monitor cytoskeletal changes during platelet activation by thrombin on fibrinogen-coated surfaces at different time ...
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Role of Actin Cytoskeletal Dynamics in Activation of the Cyclic AMP Pathway and HWP1 Gene Expression in Candida albicans
... actin cytoskeletal network that is essential for wild-type hyphal ...actin cytoskeletal dynamics during polarized morphogenesis through its physical interactions with Bni1 ...
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A new kymogram-based method reveals unexpected effects of marker protein expression and spatial anisotropy of cytoskeletal dynamics in plant cell cortex
... of Cytoskeletal Kymograms), and validated it on data from Arabidopsis thaliana fh1 formin mutants, previously shown by conventional methods to exhibit altered actin and microtubule dynamics compared to the ...
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Panx1 regulates neural stem and progenitor cell behaviours associated with cytoskeletal dynamics and interacts with multiple cytoskeletal elements
... Altogether, our data expand on our previous findings by demonstrating that Panx1 is expressed in Dcx- positive migrating neuroblasts in adult brain, and is also involved in additional cell behaviours associated with ...
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Angerilli, Alessandro (2018): Histone H4K20 methylation phases cytoskeletal dynamics with the cell cycle during Xenopus mucociliary epithelium formation. Dissertation, LMU München: Medizinische Fakultät
... post-mitotic cytoskeletal structures such as the cilium (obviously enriched in the epidermal compartment) and cell projections (Mi, Poudel et ...are cytoskeletal genes down regulated in block at NF16? A ...
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N WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination
... impaired cytoskeletal capacity to evoke the inner Schwann cell mesaxon movement that drives the elaboration of spirally wrapped membrane needed for myelin sheath ...multiple cytoskeletal anomalies ...
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Nap1 regulated cytoskeletal dynamics during cortical neuronal development
... the modification of Nap1 expression in vivo in cortical plate neurons only. . Cortices were then sliced (200μm thick) and maintained in vitro for 3 days prior .[r] ...
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Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium
... the site where most bacteria and fungi are digested. Non- digestible particles are retained in the lung for longer peri- ods of time, for example iron oxide tracer particles have a clearance half-time of 120 days in ...
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Tubulobulbar complex: Cytoskeletal remodeling to release spermatozoa
... Actin Like podosomes, TBCs comprise a core of F-actin around the tubular invagination. F-actin (filamentous actin) is a polymer and the basic unit of microfilaments. It is an assembly of G-actin (globular actin) subunits ...
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MIEN1 drives breast tumor cell migration by regulating cytoskeletal-focal adhesion dynamics
... a cytoskeletal-signaling adapter protein to drive breast cancer cell ...actin dynamics by inducing phosphorylation of FAK at Tyr-925 and reducing phosphorylation of cofilin at Ser-3, which results in breast ...
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Cytoskeletal and Signaling Dynamics Underlying Directional Persistence of Cell Migration.
... We have developed several image analysis methods for quantification of cell morphology, intracellular signaling, and cytoskeletal dynamics (Asokan et al., 2014; Johnson and Haugh, 2013; Johnson et al., ...
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α Catenin dependent cytoskeletal tension controls Yap activity in the heart
... control cytoskeletal dynamics, suggesting a positive-feedback loop may exist that maintains nuclear Yap localization (Morikawa et ...actin dynamics, which play a crucial role in junctional remodeling ...
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RacB Regulates Cytoskeletal Function in Dictyostelium spp.
... To visualize the changes in the actin cytoskeletal dynamics, WT-RacB and V12-RacB constructs were transformed into cells that constitutively express GFP-ABD. This fusion protein binds specifically to ...
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The Cytoskeletal Mechanisms of Cell-Cell Junction formation in Endothelial Cells
... To mimic cadherin interaction on single cells, we propose to utilize one of two current techniques to coat glass coverslips with specific areas of collagen or cadherin. The first technique, micropatterning, offers ...
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Zinc Alters Cytoskeletal Integrity and Migration in Colon Cancer Cells
... invasiveness, cytoskeletal integrity and expression of selected markers (E-cadherin, catenin, vimentin, tubulin and actin) of invasive SW480 colon tumor ...
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