Cytotoxic chemotherapy
Targeted antiangiogenic agents in combination with cytotoxic chemotherapy in preclinical and clinical studies in sarcoma
... with cytotoxic chemotherapy may pro- vide a valid approach to overcoming chemoresistance and inhibiting growth of these ...with chemotherapy may be ben- eficial in the treatment of patients with ...
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The management of cytotoxic chemotherapy extravasation: A systematic review of the literature to evaluate the evidence underpinning contemporary practice
... of cytotoxic chemotherapy, supported by up to date institutional policies and procedures, is a key factor in the effective prevention of extravasation (EONS 2007, UKONS 2008, Dougherty 2010, Schulmeister ...
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Monitoring dynamic cytotoxic chemotherapy response in castration resistant prostate cancer using plasma cell free DNA (cfDNA)
... Results: Peripheral blood was obtained from 15 patients with metastatic castration-resistant prostate cancer (CRPC) immediately before and after cytotoxic chemotherapy infusion. cfDNA was extracted and ...
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Is this the end of cytotoxic chemotherapy in Merkel cell carcinoma?
... of cytotoxic chemotherapy in ...leave chemotherapy as an option for those who are not candidates for or progressed after immu- notherapy, or those who are not eligible for a clinical ...with ...
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Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review
... chemo-resistant, cytotoxic chemotherapy represented the only available therapeutic option for metastatic mela- noma before the era of targeted therapies and immuno- ...Many chemotherapy regimens only ...
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Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer
... Abstract: Approximately a fifth of ovarian carcinoma (OC) is associated with inherited germline mutations, most commonly in the DNA repair genes BRCA1 or BRCA2 (BRCA). BRCA1- and BRCA2-associated OCs have historically ...
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Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer
... Some additional evidence in support of an epigenetic priming of chemotherapy response was observed in LX7 xenografts. LX7 PDXs established from vehicle and epigenetically pretreated LX7 tumors both responded ...
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Hepatitis B reactivation among 1962 patients with hematological malignancy in Taiwan
... receiving cytotoxic chemotherapy has been noted for 3 decades [3, 24, 25], especially in patients with lymphoma [4, 5], patients treated with corticosteroids [6, 7] and rituximab [8, 9], as well as in ...
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Role of TGF-β signaling in tumorigenesis
... Blockade of tumor cell transforming growth factor-betas enhances cell cycle progression and sensitizes human breast carcinoma cells to cytotoxic chemotherapy. Exp Cell Res[r] ...
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Profile of nintedanib in the treatment of solid tumors: the evidence to date
... with cytotoxic chemotherapy for indications including metastatic colorectal cancer, non-small-cell lung cancer, breast cancer, renal cell carcinoma (RCC), and gastric cancer, some are used as approved ...
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The prognostic significance of facial lymphoedema in HIV-seropositive subjects with Kaposi sarcoma
... The patient refused anti-retroviral treatment and systemic cytotoxic chemotherapy, and was temporarily lost to fol- low-up but returned to our clinic three months later. He now presented with severe oedema ...
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Tolerability of oral sorafenib in pet dogs with a diagnosis of cancer
... Within the constraints of an early phase tolerability study, response to therapy was not a primary end point. Despite this focus, hints of activity may be informative to future inves- tigators and are, as such, briefly ...
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Principles of adoptive T cell cancer therapy
... Evidence in support of the cancer stem cell hypothesis and the idea that these cells present a substantial barrier to complete tumor elimination using cytotoxic chemotherapy raises the h[r] ...
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Critical appraisal of pemetrexed in the treatment of NSCLC and metastatic pulmonary nodules
... first-line cytotoxic chemotherapy should be stopped at disease progression or after 4 cycles, in patients whose disease is stable but not responding to ...Two-drug cytotoxic combinations should be ...
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PubMedCentral-PMC5049997.pdf
... that cytotoxic chemotherapy may be more age-pro- moting than non-cytotoxic drugs used for myeloma, and is consonant with the practice of avoiding alkylating agents in patients with myelo- ma because ...
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Potential anticancer properties of bioactive compounds of <em>Gymnema sylvestre</em> and its biofunctionalized silver nanoparticles
... Many plant-derived saponins, eg, ginsenosides, soy- asaponins, and saikosaponins, have been found to exhibit significant anticancer activity. The anticancer activity of gymnemagenol on HeLa cancer cell lines in in vitro ...
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Cytotoxic activity screening of ethyl acetate fungal extracts derived from the marine sponge Neopetrosia chaliniformis AR-01
... Two cell lines, WiDr as a colon adenocarcinoma cell line, and Vero as normal cell line were prepared for cytotoxic assay using MTT. All cell lines were obtained from Laboratory of Parasitology at Gajah Mada ...
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The relationship between cancer patient's fear of recurrence and chemotherapy : a systematic review and meta analysis
... There has been a dramatic improvement in the survival of cancer patients over the last two decades. The use of combined modalities of treatment, such as surgery, chemotherapy and radiotherapy has brought great ...
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Preexposure of MCF-7 breast cancer cell line to dexamethasone alters the cytotoxic effect of paclitaxel but not 5-fluorouracil or epirubicin chemotherapy
... doses of GCs, most commonly dexamethasone (Dex), are frequently administered throughout the course of chemotherapeutic treatment for solid tumors in order to reduce toxicity and to protect normal tissue from the negative ...
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“Phytochemical, Antibacterial and Cytotoxic Screening of Salicia fruticosa Heyne Ex Lawson., Aerial Parts - in vitro Model” by Dhanalakshmi M, Prabhavathi.K, Pradeepti.K.G, Manjula Devi K, Senthil Rajan D, India.
... and cytotoxic properties of medicinal plant frequently used in Indian traditional ...vitro cytotoxic activity of EAC and DLA cell line using different concentration to find the % cell death by various ...
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