cytotoxic t cells
Analysis of T cell responses in liver allograft recipients Evidence for deletion of donor specific cytotoxic T cells in the peripheral circulation
... recipient cells with semisyngeneic cells having both donor and third-party HLA antigens failed to reveal the presence of cytotoxic T cells (CTL) specific to the donor, whereas the CTL ...
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Perforin Expression in Theileria parva Specific Cytotoxic T Cells Correlates with Cytotoxicity
... positive cells correlated with the cytotoxicity when the target cells were pulsed with the peptide used in the ...positive cells and the net MFI of the ...of T cell receptors (TCRs) per cell ...
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Tumor infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
... of T cell ...suppressor cells (MDSCs) are a source of the free radical peroxynitrite ...tumor cells with PNT or with MDSCs inhibits binding of processed peptides to tumor cell–associated MHC, and as ...
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Preliminary evidence of reductive stress in human cytotoxic T cells following exercise
... these cells post-exercise (8, 43–45, 48). Both types of T-lymphocyte are antigen specific, where CD4 + T-cells serve broadly to orchestrate the immune response via cytokine production and CD8 ...
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Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells
...  T ⫺ d I and observe that steady state requires that the killing rate balances replication, ...infected cells (19, ... T(0) ⫺ d I , and the initial downslope of the viral load during an effective ...
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Lysis of myotubes by alloreactive cytotoxic T cells and natural killer cells Relevance to myoblast transplantation
... blood cells were used as a source of NK ...NK cells was inhibited by depleting peripheral blood cells of CD16+ cells with anti-CD16 MAb and ...
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MUC1 Antigen Specific CD8 T Lymphocytes Targeting MCF7 and MDA MB 231 Human Breast Adenocarcinoma Cell Lines
... of T cell activation, IFN γ production, T cell proliferation and development of cytotoxic T cells ...CD8 T cells do not produce large amounts of IFN- γ , but ...
15
CD4+ T Cells Develop Antiretroviral Cytotoxic Activity in the Absence of Regulatory T Cells and CD8+ T Cells
... ⫹ T cells might be able to compensate for the lack of cytotoxic T cells in CD8-depleted mice, especially when no Tregs were present to modulate their ...⫹ T cells alone ...
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Decreased severity of collagen antibody and lipopolysaccharide- induced arthritis in human IL-32β overexpressed transgenic mice
... of cytotoxic T cells and NK ...NK cells and dendritic cells that are important for the innate immune system by CAIA and LPS was reduced by ...marrow cells derived from the Tg ...
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Induction of Autoreactive CD8+ Cytotoxic T Cells during Theiler's Murine Encephalomyelitis Virus Infection: Implications for Autoimmunity
... mock-infected cells into 7 control mice or of TMEV-induced autoreactive cells into 10 mice did not induce CNS ...antigen-positive cells were found in the lesions or in other parts of the CNS ...
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Induction of antigen specific human cytotoxic T cells by Toxoplasma gondii
... of T cells in immunity to the parasite Toxoplasma gondii, antigen-specific T cell clones were generated using peripheral blood mononuclear cells from seropositive ...antigen-reactive ...
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Immunoregulatory T cells in man Histamine induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T cells
... activate T suppressor cells that bear the Leu 2 (OKT8) ...distinguish cytotoxic T cells from antigen-specific suppressor T ...2+ cells isolated from peripheral blood were ...
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Distribution and functions of γδ T cells infiltrated in the ovarian cancer microenvironment
... γδ T cells are major MHC-unrestricted T lympho- cytes that are widely distributed in peripheral blood (PB) and mucosal tissues with limited ...γδ T (Vδ1 T cells) and Vδ2 γδ ...
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Original Article Transformations of peripheral T cell subset distributions in oral cancer patients and the effect of P53 gene therapy in a short time
... functions, T cells must be ...Tc cells leads to rapid clonal expansion and differentiation of effector T ...Th cells [27]. We found a significantly higher percent- age of activated ...
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Cytotoxic T cells and viral hepatitis
... recognition, T cell–hepatocyte binding affinity, and hepatocellular ...fected cells (44), raising the possibility that HCV might do the ...infected cells, for the quantitative reasons discussed ...
7
Natural regulatory T cells inhibit production of cytotoxic molecules in CD8+T cells during low level Friend retrovirus infection
... of cytotoxic CD8 + T cells ...+ T cell cytotoxicity, whereas the mechanisms that suppress the production of cytotoxic molecules in low-level virus infections were ...
6
Bowman’s capsule provides a protective niche for podocytes from cytotoxic CD8+ T cells
... Jedi T cells, EGFP + podocyte transgenic mice showed enhanced proteinuria and higher blood urea ...+ T cell infiltrates that were in direct contact with EGFP + podocytes, causing their ...
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Analysis of T Cell Responses during Active Varicella-Zoster Virus Reactivation in Human Ganglia
... infiltrating T cells showed a large number of infil- trating CD4 ⴙ T cells and cytolytic CD8 ⴙ T ...infiltrating T cells were closely associated with neurons within the ...
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In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells
... HCC cells-specific CTL by DCs/allo-HCC To determine whether HCC cells-reactive T cells are induced by fusion cells, T cells from healthy donors were stimulated by fusions ...
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Functional studies on human γδ T cells and their interactions with dendritic cells and B cells
... γδ T cells have attracted interest as immunotherapeutic agents owing to their ability to respond rapidly when faced with a wide array of pathogens or transformed cells, without the requirement for ...
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