D. discoideum
Meier, Börn (2012): CHEMOTACTIC GRADIENT GENERATOR - A microfluidic Approach on how D. discoideum change direction. Dissertation, LMU München: Fakultät für Physik
... Figure 2.3: Regulatory network of the chemotactic response in D. discoideum. (a) G proteins connected to the cAMP receptor cAR simultaneously activate multiple signaling cascades that are involved in the ...
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Dictyostelium discoideum and autophagy – a perfect pair
... In D. discoideum we found massive transcriptional changes and complex phenotypes of varying severity for ATG12‾, ATG16‾ and ATG12‾/16‾ knock-out cells implying that ATG12 and ATG16 have, in addition to ...
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Characterization of mutant myosins of Dictyostelium discoideum equivalent to human familial hypertrophic cardiomyopathy mutants Molecular force level of mutant myosins may have a prognostic implication
... tile properties are the characteristics of the second one, F506C. F506 is located on a long a-helix away from the actin-binding site and the ATPase pocket (11, 30). This helix is composed of the longest ...
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Characterization of the Roco Protein Family in Dictyostelium discoideum
... Dictyostelium discoideum (Dd), Dictyoste- lium purpureum (Dp), Dictyostelium fasciculatum (Df), and Polysphondylium pallidum (Pp), using human LRRK2 as an outgroup ...in D. discoideum, which suggests ...
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Microbiome management in the social amoeba Dictyostelium discoideum compared to humans
... The D. discoideum genome contains four discoidin I genes, dscA, dscC, and dscD that produce lectins belonging to discoidin I (DiscI) family, and the dscE gene that produces the discoidin II lectin ...
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Evolutionary crossroads in developmental biology: Dictyostelium discoideum
... in D. discoideum are well suited to investigate its signalling pathways, in practice these approaches are time- consuming and technically challenging, making progress ...in D. discoideum to ...
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Small molecules and cell differentiation in Dictyostelium discoideum
... Terpenes are also structurally diverse secondary metabolites and are involved in ecological interactions, including defence against predators and formation of mutually beneficial alliance with other organisms. Terpenes ...
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Cooperation and conflict in the social amoeba Dictyostelium discoideum
... In animals, contests and fights are often won by the largest individuals or those in the best condition. Consistent with this, D. discoideum cells fed glucose are more likely to become spores over those ...
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The Dictyostelium discoideum RACK1 orthologue has roles in growth and development
... For S. cerevisiae it is reported that the RACK1 ortho- logue Asc1p functions as a Gβ subunit for a Gα (Gpa2) [30]. Similarly, in the human pathogenic fungus C. neoformans the RACK1 orthologue Gib2 functions as Gβ for ...
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A multi host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58 lacking full virulence
... of D. discoideum cells on the lawn of these mutants, whereas only the highest amoeba concentrations could produce small phagocytic plaques when using the wild-type bac- terium ...
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Evolutionary reconstruction of pattern formation in 98 Dictyostelium species reveals that cell-type specialization by lateral inhibition is a derived trait
... In D. discoideum, the non-prespore cells at the rear- guard will form the basal disc and lower cup that support the base of the stalk and the spore head, ...
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Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum
... Dictyostelium discoideum and it was owing to use of D. discoideum as a model system that it was first proved that FDPS is the target for the drugs ...(Dictyostelium discoideum FDPS) is closely ...
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The Dictyostelium discoideum model system
... of D. discoideum has allowed in recent years the expansion of our knowledge to other areas, including cell biology and many others related to human ...where D. discoideum acts as a very ...
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The endocytic pathways of Dictyostelium discoideum
... As the contents of macroendosomes are destined for degrada- tion the rescue of cell surface components before their digestion is important for continued cell function. This is achieved by the combined action of sorting ...
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Parasexual genetics of Dictyostelium gene disruptions: identification of a ras pathway using diploids
... Background A large body of work in the 1970s and 1980s showed that parasexual recombination of haploid Dictyostelium discoideum strains was a potent tool for generating multiple mutants [r] ...
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Tel-1 transposon-like elements of Tetrahymena thermophila are associated with micronuclear genome rearrangements.
... tion fragment length polymorphisms detected by a DRE-1 probe are associated with movement of these elements in Dictyostelium discoideum (MARSCHALEK et al. The variation [r] ...
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NEW LOCI IN DICTYOSTELIUM DISCOIDEUM DETERMINING PIGMENT FORMATION AND GROWTH ON BACILLUS SUBTILIS
... Linkage analysis in Dictyostelium discoideum using multiply marked tester strains: establishment of linkage group VI1 and the reassessment of earlier linkage data.. whi[r] ...
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Dictyostelium discoideum: a model system for differentiation and patterning
... Escalante 1 pm Dictyostelium as a developmental system 819 Review Dictyostelium discoideum a model system for differentiation and patterning RICARDO ESCALANTE* and JUAN J VICENTE Instituto de Investig[.] ...
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Paxillin and Phospholipase D Interact To Regulate Actin-Based Processes in Dictyostelium discoideum
... Two such proteins involved in actin-dependent processes are paxillin and phospholipase D (PLD). Paxillin acts as an adapter and anchor protein by recruiting diverse structural and signaling proteins into a complex ...
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PldB, a Putative Phospholipase D Homologue in Dictyostelium discoideum Mediates Quorum Sensing during Development
... Dictyostelium discoideum, is required for efficient entry into the differentiation and development segment of its life ...phospholipase D (PLD) homologue, in quorum ...
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