D-optimal design
Linagliptin loaded Solid-SMEEDS for enhanced solubility and dissolution: Formulation development and optimization by D-optimal design
... using D-optimal Design D-optimal mixture design was used as a statistical tool to understand the relationship between formulation variables and response ...
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Selectively increasing of polyunsaturated (18:2) and monounsaturated (18:1) fatty acids in Jatropha curcas seed oil by crystallization using D-optimal design
... In this study, variations of factors that affect the urea complex fractionation such as the ratio of urea-to-FAs (w/w), crystallization temperature (°C) and crystallization time (h) were examined to obtain optimum ...
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Optimization Of Clay-Bonded Graphite Crucible Using D-Optimal Design Under Mixture Methodology
... D-optimal design under the mixture methodology was employed to optimize the mixture and process ...The design was performed using design expert software ...
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D-Optimal Design for Logistic Regression Model with Three Independent Variables
... considering D-optimal criterion, appropriate models were introduced and, based on a logistic regression model with three independent variables and dependence of information matrix on passive parameters, a ...
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Optimization of Monolayer Hydrophilic Matrix Tablets Containing Nisoldipine Solid Dispersion Using D-optimal Design
... a D-optimal design was justified by the fact that a continuous variation in weight of the matrix tablet might result in different surface area of the tablets and might act as a key variable to affect ...
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D-optimal Design and Development of Microemulsion Based Transungual Drug Delivery Formulation of Ciclopirox Olamine for Treatment of Onychomycosis
... This design provided a 10 run empirical model to describe the effect of formulation ingredient on the globule size (D50), transungual drug permeation flux, and nail drug loading from microemulsion ...experimental ...
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Optimization of Moisturizing Clay Soap Containing Pitaya (Hylocereus Polyrhizus) Seed Extract using D Optimal Mixture Experimental Design
... The design was implemented by combining 6 different independent variables: cocoa butter, virgin coconut oil, olive oil, palm oil, water and caustic ...the D-optimal mixture experimental design ...
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SIMULTANEOUS DETERMINATION OF KETOROLAC TROMETHAMINE AND OLOPATADINE-HCl IN PURE FORM, MARKETED TABLETS AND NEW FORMULATED FAST DISSOLVING FILMS
... Experimental design: D-optimal design was applied and the material attributes and response variables were studied and related to determine the effect of each factor on the determined responses ...
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Hydrolysis optimization and characterization study of preparing fatty acids from Jatropha curcasseed oil
... of ethanolic KOH (M), reaction temperature (°C), and reaction time (h), respectively. The settings for the inde- pendent variables were as follows (low and high values): KOH concentration of 1.00 and 2.00 M; hydrolysis ...
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Optimal Raw Material Mix for the Production of Rice Husk Ash Blended Cement
... The D-optimal design is a statistical approach for use with categorical factors as an alternative to the general factorial design option Design Expert, 2013 ...The ...
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<p>Eudragit<sup>®</sup>-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers</p>
... The current work aimed at developing and optimizing a promising etoricoxib-loaded nanosystem for colon tar- geting applying the D-optimal design via nano-spray dry- ing technique using poly ...
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Application of D Optimal Study Design with Contour Surface Response for Designing Sustained Release Gliclazide Matrix Tablets
... the optimal excipient compo- sition for achieving the optimized formulation ...advantages, D-optimal design with a polynomial quadratic statistical model instead of a quadratic model was used ...
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Design and Optimization of Controlled Release Felbamate Tablets by D-optimal Mixture Design: In vitro-in vivo Evaluation
... using D-optimal design, which can elucidate the effect of all variables simultaneously during formulation ...by D-optimal ...by D-optimal design have potential to ...
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Optimization on the Stability of Linseed Oil-in-Water Nanoemulsions Generated by Ultrasonic Emulsification Using Response Surface Methodology (RSM)
... particularly D-optimal design, was used to study the effects of independent variables: dispersed phase ratio (X1), HLB (X2) and emulsifier ratio (X3) on the droplet size and viscosity of Linseed oil ...
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Compound optimal designs for percentile estimation in dose response models with restricted design intervals
... an optimal design ξ with respect to some criterion function Φ(·) lie outside a reasonable dosage range, ...restricted design intervals into ...on optimal design for the binary response ...
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Minimax and admissible adaptive two-stage designs in phase II clinical trials
... two-stage design for use in phase II clinical trials to assess the new treat- ment’s ...adaptive optimal design by Shan et al. [8]. The proposed design allows the second stage sample size and ...
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Optimal design and analysis of wireless power transfer system with converter circuit
... Generally, power transfer efficiency is as the objective function under some constrains, such as the volume of the receiver coil or the power transfer distance. Accord- ing to the application background, sometimes, the ...
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SERVICE QUALITY IMPACT ON CUSTOMER SATISFACTION - A STUDY OF ICICI BANK IN MYSORE CITY
... The problem of optimal pole-placement has been generally solved only in the case of single-input linear systems [8]. For the case of multi-input systems a method deals with system eigen values as a whole and ...
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The optimal design of a fiscal union
... of optimal monetary and fiscal policy among interdependent economies, particularly within a currency ...for optimal policy in their dynamic model, they log-linearize around the Cole-Obstfeld (1991) steady ...
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The optimal design of rewards in contests
... ments have been analyzed before both positively, studying the equilibrium behavior properties and normatively, determining what are optimal contest designs. Environments with complete information have been ...
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