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Db/db, adipose tissue

DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid

DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid

... in db/ db ...of db/db mice fed an SL diet and increase of SDF-1α, BNP, or other DPP-4 target factors by DPP-4 inhi- bition might be involved in longevity of those ...of db/db ...

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Original Article Increased SPARC expression in skeletal muscle and adipose tissue of db/db mice

Original Article Increased SPARC expression in skeletal muscle and adipose tissue of db/db mice

... by adipose tissue, which has been recently linked with insulin resistance and glucose ...in adipose tissue and skeletal muscle of db/db and control ...in adipose ...

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Oral Quercetin Supplementation Lowers Plasma sICAM 1 Concentrations in Female db/db Mice

Oral Quercetin Supplementation Lowers Plasma sICAM 1 Concentrations in Female db/db Mice

... in adipose tissue via a PPAR-γ- independent mechanism ...The db/db mouse is a well-established animal model for non-insulin dependent diabetes mellitus (NIDDM) in man, characterized by ...

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Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney

Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney

... Furthermore, the target genes regulated by the 7 miR- NAs identified were subjected to KEGG pathway enrich- ment. Our study showed that T2DM; renal cell carcinoma; AMPK signaling pathway; PI3K-Akt signaling pathway; ...

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Chronic stress aggravates glucose intolerance in leptin receptor-deficient (db/db) mice

Chronic stress aggravates glucose intolerance in leptin receptor-deficient (db/db) mice

... subordinate db/db mice showed a systemic low- grade pro-inflammatory profile, as suggested by elevation of TNF-alpha levels and mild increase in IL-6 levels, in line with results in wild-type mice ...

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Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration in diabetic BKS db/db mice

Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration in diabetic BKS db/db mice

... AD-MSCs: Adipose tissue-derived mesenchymal stem cells; BDNF: Brain-derived neurotrophic factor; CD3: Cluster of differentiation 3; CD11b: Cluster of differentiation 11b; CM: Conditioned medium; CMAP: ...

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Glucose transporter levels in spontaneously obese (db/db) insulin resistant mice

Glucose transporter levels in spontaneously obese (db/db) insulin resistant mice

... muscle/adipose tissue glucose transporter (GLUT-4) in various tissues of spontaneously obese mice (C57BL/KsJ, db/db) and their lean littermates ...in db/+, P less than ...in ...

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Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice

Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice

... Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver disease affecting 15–40% of the general adult population [1]. NAFLD is closely linked to obesity, type 2 diabetes and other metabolic ...

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Liraglutide reduces lipogenetic signals in visceral adipose of db/db mice with AMPK activation and Akt suppression

Liraglutide reduces lipogenetic signals in visceral adipose of db/db mice with AMPK activation and Akt suppression

... Abstract: Liraglutide, a glucagon-like peptide-1 analog, has been proved to reduce body weight and visceral adipose tissue (VAT) in human studies. In this study, we aimed at exam- ining lipogenetic signal ...

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Original Article Alpinia oxyphylla Miq. extract changes microRNA expression profiles in db-/db- mouse livers

Original Article Alpinia oxyphylla Miq. extract changes microRNA expression profiles in db-/db- mouse livers

... [13]. Although significant numbers of miRNAs have been identified in such studies, only a few are likely to be important therapeutic targets. Alpinia oxyphylla Miq. is regarded as a sought- after drug in the herbal ...

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Expression of the oxygen regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport

Expression of the oxygen regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport

... Wound tissue was dissected using 10-mm skin biopsy punches 5 days after the ...granulation tissue and the ratio of GFP-positive cells to F4/80-positive cells were counted by two investigators blinded to the ...

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Packing Anti debugging Reversing pdf

Packing Anti debugging Reversing pdf

... DbgNotFoundTitle db "Debugger status:",0h DbgFoundTitle db "Debugger status:",0h DbgNotFoundText db "Debugger not found!",0h DbgFoundText db "Debugger found!",0h .code start: ASSUME FS:N[r] ...

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Cyber Database Control System Ver 2 Application Programming Ref Man 60485300D Apr86 pdf

Cyber Database Control System Ver 2 Application Programming Ref Man 60485300D Apr86 pdf

... DB$LKAR Routine Format DB$RPT Routine Format DB$SIR Routine DB$VERS Routine Format COBOL Example Showing Use of Version Master and an Alternate Version 2-19 DB$WAIT Routine Format 2-20 D[r] ...

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Privacy Access Policy for Mongo DB

Privacy Access Policy for Mongo DB

... NoSQL datastores are emerging non relational databases committed to provide high security for database operations over several servers. These platforms are getting increasing attention by companies and organizations for ...

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Implementation of ARM in Distributed DB

Implementation of ARM in Distributed DB

... 1) Selecting the products available in the catalog and request to the administrator to process the purchase of the product. 2) Each customer can have their own user id otherwise [r] ...

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Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα

<p>Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-&kappa;B p65 Nuclear Translocation and the Ubiquitination and Degradation of I&kappa;B&alpha;</p>

... 3 Db/db mice are a spontaneous mutation in the 129 C57BL/Ks mouse colony that induces moderate hyperphagia and obesity, accompanied by severe fasting hyperglycaemia that increases with age and a marked ...

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Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice

Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice

... During progression to diabetes islet structure degenerate [13]. To evaluate if EGCG and/or rosiglitazone were able to prevent islet degeneration in the db/db mouse model we used light microscopy to examine ...

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Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

... limiting enzyme of the PPAR α -regulated and peroxisome proliferator-inducible fatty acid β -oxidation system. Our results showed that BBR-SLNs effectively inhibited SCD1, FAS, and SREBP1c expression (P,0.05) following ...

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Parametric studies on effects of defected ground structure (DGS) for dual band bandstop microstrip filter

Parametric studies on effects of defected ground structure (DGS) for dual band bandstop microstrip filter

... Abstract. A dual-band bandstop microstrip filter is proposed and designed by using microstrip resonator with Defected Ground Structure (DGS). The DGS are placed in the ground plane to obtain high attenuation of the ...

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Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists  A novel treatment strategy

Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists A novel treatment strategy

... Treatment of db/db mice with A717 significantly reduced the proteinuria (1.52 +/- 0.3 mg/mg creatinine), inhibited mesangial matrix expansion, and attenuated overexpression of matrix mRNAs. The nephropathic ...

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