Death, Mechanism Of
RIP Kinase-Mediated Necrosis as an Alternative Mechanism of Photoreceptor Death
... a mechanism of photoreceptor death, previous morphological analyses demonstrated the presence of photoreceptor necrosis as well as apoptosis after retinal detachment and retinal photic injury ...cell ...
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Mechanism of sudden cardiac death in patients with heart failure
... perfused isolated hearts where the right ventricular out flow tract shows the longest APD (Benoist et al., 2012). Conduction abnormalities are commonly found in right heart failure and are linked not only to changes in ...
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Mitotic death: a mechanism of survival? A review
... In conclusion, after extensive DNA damage, p53 mutated cells miss DNA repair and apoptosis at the G1 and S phase checkpoints and accumulate at the G2 arrest com- partment with point mutations and chromosome breaks. The ...
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The mechanism of low concentration sodium nitroprusside mediated protection of chondrocyte death
... signaling mechanism involved in low-concen- tration SNP-mediated cytoprotection, cGMP dependence was first ...cell death induced by 1 mM SNP, indicating a cGMP-mediated cytoprotective ...SNP-induced ...
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Evaluating an educational intervention to improve the accuracy of death certification among trainees from various specialties
... the mechanism of death without an underlying disease as the cause of death; (ii) improper temporal sequencing of events; (iii) listing two causally unrelated, etiologically specific diseases as the ...
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<p>Targeting off-target effects: endoplasmic reticulum stress and autophagy as effective strategies to enhance temozolomide treatment</p>
... mechanism of ER stress and autophagy transition between pro-survival and pro-apoptosis roles to ultimately determine cell fate. Under low doses and short-term TMZ treatment, ER stress and autophagy may have a ...
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Oncolytic Vesicular Stomatitis Virus Induces Apoptosis in U87 Glioblastoma Cells by a Type II Death Receptor Mechanism and Induces Cell Death and Tumor Clearance In Vivo
... the death receptor and mitochondrial apoptotic pathways is required for efficient in- duction of cell ...death. Death receptor signaling has been clas- sified as type I or type II, depending on ...
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Occurrence and Mechanisms of Sudden Oxygen Desaturation in Infants Who Sleep Face Down
... infant death syndrome. It has been suggested that 1 mechanism of death in this situation involves rebreathing of expired ...the mechanism of these desaturations, and 3) to determine the timing ...
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Cardiac death after extreme physical and mental trauma—case report
... cardiac death immediately after intense physical and mental stress are occasionally described, known as “ stress- related sudden deaths ” ...of death and mechanism of death, is the ...
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Targeting Tumour-Initiating Cells with TRAIL Based Combination Therapy Ensures Complete and Lasting Eradication of Multiple Myeloma Tumours In Vivo
... In the present study we have shown that both CD138 + and CD138 2 cells, derived from either cell lines or from patient samples, are susceptible to the actions of TRAIL, DOX and DEX. Of note these cells were more ...
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Breast cancer: Small molecules targeting apoptosis, a prospective approach to safe scientific success
... The mitochondrial pathway of apoptosis is the major mechanism of physiological cell death in vertebrates. In this pathway, proapoptotic members of the Bcl-2 family (contain only a BH3 domain) cause ...
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Quality of death notification forms in North West Bank/Palestine: a descriptive study
... to death, (ii) competing causes of death occurs when two or more causally unrelated, etio- logically specific diseases listed in part 1 of the DNF, (iii) unacceptable cause of death is documented ...
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Fear Avoidance as the Body’s Defence Mechanism for Death
... the mechanism of fear avoidance is a well-known concept that has been substantiated through international literature in the ...to death and can be defined in the following way: fear of death/distress ...
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Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase
... GR induces neuronal superoxide production after HG. (A) Neuronal superoxide production as imaged by Et fluo- rescence in rat brain hippocampal sections after sham HG (Sham), 60 minutes of HG without GR (HG only), or 30 ...
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Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts
... Celecoxib does not induce caspase activation in rheumatoid arthritis fibroblast-like synoviocytes (RA FLSs). (a) FLSs were stimulated for 2 hours with celecoxib at indicated concentrations or for 4 hours with tumor ...
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Tauroursodeoxycholic Acid Prevents Amyloid-β Peptide-Induced Neuronal Death Via a Phosphatidylinositol 3-Kinase-Dependent Signaling Pathway
... The role of apoptosis in Aβ-induced toxicity suggests that its modulation may slow the neurodegenerative process. The endogenous hydrophilic bile acid ursodeoxycholic acid (UDCA) and its taurine-conjugate ...
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Defining the chemical and molecular mechanisms of cytotoxicity Induced by the endoperoxide class of antimalarials
... Artemisinin-derived endoperoxide drugs are routinely employed as frontline treatment in the fight against malaria. Their use in combination regimens provides highly effective therapy against parasite strains displaying ...
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Original Article The cell death of C6 astrocytoma cells induced by oridonin and its mechanism
... Abstract: Many studies have shown that oridonin, a compound purified from Rabdosia rubescens, was able to suppress proliferation and induce apoptosis in many cell types. In this study, In order to investigate the ...
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Basic biological aspects of Tritrichomonas foetus of re levance to the treatment of bovines suffering of tricho moniasis
... of super cells expressed in the development and eradica- tion of others, defective [72]. Teratogenic transforma- tions, microbial infections, lethal factors such as heat, mutagens and oxidants agents, and toxins induce ...
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The relation between alcohol and cardiovascular disease in Eastern Europe: explaining the paradox.
... used information provided in 1953 by 2073 Finnish men on drinking habits including frequency, intoxication, hangovers, hangover drinking (morning drinks) and black- outs. After a 12 year follow up, compared with never ...
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