decay-accelerating factor (CD55)
Hantavirus Causing Hemorrhagic Fever with Renal Syndrome Enters from the Apical Surface and Requires Decay-Accelerating Factor (DAF/CD55)
... entry. Decay-accelerating factor (DAF)/CD55 is a GPI-anchored protein of the complement regulatory system and serves as a receptor for attachment to the apical cell surface for a number of ...
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Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury
... Decay-accelerating factor (DAF, also known as CD55), a ubiquitously expressed intrinsic complement regulatory protein, inhibits complement activation by inhibiting the function of C3/C5 ...
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Interaction between echovirus 7 and its receptor, decay-accelerating factor (CD55): evidence for a secondary cellular factor in A-particle formation.
... of decay-accelerating factor (DAF) (CD55), the receptor for echovirus 7, were synthesized in the yeast Pichia ...secondary factor(s) may contribute to A-particle formation and uncoating ...
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Decay-Accelerating Factor Binding Determines the Entry Route of Echovirus 11 in Polarized Epithelial Cells
... and decay-accelerating factor (DAF or CD55) at the apical surface of polarized Caco-2 cells results in rapid transport of the virus to tight junctions and in its subsequent ...
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Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection
... characterized by loss of acetylcholine receptors (AChR’s) due primarily to the production of anti-AChR autoantibodies. In this study we investigated whether the presence of decay- accelerating factor ...
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Single Amino Acid Changes in the Virus Capsid Permit Coxsackievirus B3 To Bind Decay-Accelerating Factor
... CB interact with at least two receptors. All isolates so far examined attach to the coxsackievirus and adenovirus receptor (CAR), a 46-kDa transmembrane protein that also serves as a receptor for many adenoviruses (2, ...
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Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry.
... co- factor protein CD46 or to the membrane-organizing external spike protein moesin; coexpression of both molecules results in a more productive infection ...of decay-accelerating factor (DAF; ...
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Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity
... Decay-accelerating factor (DAF) is involved in the cell membrane attachment of many human enteroviruses. Presently, further specific active roles of DAF in mediating productive cell infection and in ...
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Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor
... Decay-accelerating factor (DAF) mediates cellular attachment for many human picornaviruses. In most cases, viral binding to DAF is itself insufficient to permit cell infectivity, with a second, ...
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Dr(a ) polymorphism of decay accelerating factor Biochemical, functional, and molecular characterization and production of allele specific transfectants
... on decay accelerating factor (DAF), a glycosyl-phosphatidylinositol-anchored membrane protein that protects host cells from complement-mediated ...
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Synthesis of aberrant decay accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes
... Paroxysmal nocturnal hemoglobinuria (PNH) leukocytes fail to express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal cells. To further investigate the ...
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Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
... Background: Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage ...
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Decay accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions
... Decay-accelerating factor DAF is a constitutively expressed plasma membrane glycoprotein on blood cells and endothelium that inhibits cell surface C3/C5 convertase formation, thus inhibi[r] ...
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Interaction with Decay-Accelerating Factor Facilitates Coxsackievirus B Infection of Polarized Epithelial Cells
... All coxsackie B (CB) viruses can initiate infection by attaching to the coxsackievirus and adenovirus receptor (CAR). Although some CB isolates also bind to decay-accelerating factor (DAF), the role ...
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Interaction of Decay-Accelerating Factor with Echovirus 7
... Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. ...
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Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.
... identify decay accelerating factor as a major cell attachment receptor for coxsackieviruses B1, B3, and ...human decay acceleration factor on the surface of nonpermissive murine ...
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Decay accelerating factor protects human tumor cells from complement mediated cytotoxicity in vitro
... the decay- accelerating factor (DAF), a membrane regulatory protein that protects blood cells from autologous complement ...venom factor-treated ...
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The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... (18). Decay-accel- erating factor (DAF, CD55) is recognized as the cellular re- ceptor for at least six echovirus serotypes (3, 51) and as a receptor for coxsackieviruses B1, B3, and B5 (5, ...
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Statin induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti inflammatory actions of statins in rheumatoid arthritis
... proteins decay- accelerating factor (DAF, CD55), membrane cofactor protein (MCP, CD46), complement receptor-1 and CD59 provide protection from autologous complement-mediated injury ...
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Focal and segmental glomerulosclerosis induced in mice lacking decay accelerating factor in T cells
... significantly correlated. These data are strong evidence that extra- renal DAF deficiency dictates whether FSGS ensues or not, while local DAF deficiency is of considerably less consequence. Recur- rence of proteinuria ...
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