Decay Accelerating Factor (DAF)
Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor
... surface-expressed decay- accelerating factor (DAF), but for most of these viruses this interaction is insufficient to mediate cell infection (5, 6, 12, 38, 40, 41, ...that DAF functions ...
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Decay accelerating factor protects human tumor cells from complement mediated cytotoxicity in vitro
... the decay- accelerating factor (DAF), a membrane regulatory protein that protects blood cells from autologous complement ...While DAF was undetectable among neuroblastomas, it was ...
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Hantavirus Causing Hemorrhagic Fever with Renal Syndrome Enters from the Apical Surface and Requires Decay-Accelerating Factor (DAF/CD55)
... entry. Decay-accelerating factor (DAF)/CD55 is a GPI-anchored protein of the complement regulatory system and serves as a receptor for attachment to the apical cell surface for a number of ...
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Dr(a ) polymorphism of decay accelerating factor Biochemical, functional, and molecular characterization and production of allele specific transfectants
... on decay accelerating factor (DAF), a glycosyl-phosphatidylinositol-anchored membrane protein that protects host cells from complement-mediated ...in DAF and to characterize the basis ...
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Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection
... of decay- accelerating factor (DAF or CD55), an intrinsic complement regulator, protects against the development of ...neuromuscular DAF protein) and their Daf1 +/+ littermates by ...
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Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity
... Decay-accelerating factor (DAF) is involved in the cell membrane attachment of many human ...of DAF in mediating productive cell infection and in the pathogenesis of natural enterovirus ...
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Interaction with Decay-Accelerating Factor Facilitates Coxsackievirus B Infection of Polarized Epithelial Cells
... to decay-accelerating factor (DAF), the role of DAF interaction during infection remains ...CAR, DAF was present on the apical surface of polarized cells and that ...
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Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury
... Decay-accelerating factor (DAF, also known as CD55), a ubiquitously expressed intrinsic complement regulatory protein, inhibits complement activation by inhibiting the function of C3/C5 ...
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Synthesis of aberrant decay accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes
... express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal ...the DAF defect in affected cells, patients' polymorphonuclear and ...
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Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
... Background: Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage ...
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Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.
... that DAF is highly expressed on most mamma- lian cells (1, 17, 21, 25, 37), we postulate that the cell and tissue tropism of CB1, CB3, and CB5 is governed by the presence or absence of specific accessory and ...
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Decay-Accelerating Factor Binding Determines the Entry Route of Echovirus 11 in Polarized Epithelial Cells
... Both viruses initiate entry via the apical surface, suggest- ing that both attachment receptors must be located there, but with respect to the entry pathway, the similarities end there. EV11-207 transits rapidly to tight ...
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The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... of DAF expression was too low for us to detect virus binding above background ...that DAF expression is sufficient for EV70 to productively infect NIH 3T3 ...that DAF-expressing cells were able to ...
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Focal and segmental glomerulosclerosis induced in mice lacking decay accelerating factor in T cells
... In subsequent experiments in which normal C57BL/6 mice were passively administered varying doses of anti-podo Abs, sheep IgG and mouse C3 were identified bound to the glomerular capillary wall. In the subsequent ...
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Increased expression of complement decay accelerating factor during activation of human neutrophils
... surface DAF from patients with paroxysmal nocturnal hemoglobulinuria failed to increase DAF ...that DAF deficiency in affected cells involves abnormal synthesis or packaging of DAF for ...
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The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface
... and DAF were identified by determining which atoms on the virus and receptor surfaces were within ...of DAF on the ...bound DAF molecule links two adjacent viral capsid protomers by binding to the ...
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Interaction with Coxsackievirus and Adenovirus Receptor, but Not with Decay-Accelerating Factor (DAF), Induces A-Particle Formation in a DAF-Binding Coxsackievirus B3 Isolate
... 13, DAF fraction 15, HveB fraction 15, unheated control virus fraction 15, and heated control virus fraction 14) was analyzed by plaque assay on HeLa cell ...
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Decay accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions
... express DAF antigen. The percentage of DAF-positive SMC ranged from 20 to 60% between different patient samples and SMC DAF expression was limited to SMC in the lesion ...no DAF-specific ...
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Interaction of Decay-Accelerating Factor with Coxsackievirus B3
... to DAF may be demonstrated by plaque forma- tion in RD cells, although it is unclear whether the virus uses only DAF or an unknown canyon-binding receptor to enter RD ...with DAF inhibits plaque ...
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Interaction of Decay-Accelerating Factor with Echovirus 7
... of DAF complexed with ...pocket factor and its hydrophobic ...pocket factor is shown in green, and the pocket factor (orange) is shown as a model of lauric ...representing DAF bound to ...
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