Decoy Receptor
Diagnostic value of decoy receptor 3 combined with procalcitonin and soluble urokinase-type plasminogen activator receptor for sepsis
... Decoy receptor 3 (DcR3) is a new member of the tumor necrosis factor receptors superfamily, which competitively binds Fas ligand, LIGHT and TL1A to block apop- ...
10
Decoy receptor 3 (DcR3) overexpression predicts the prognosis and pN2 in pancreatic head carcinoma
... status. Decoy receptor 3 (DcR3), a newly discovered member of the tumor necro- sis factor receptor (TNFR) superfamily, is regarded as a secreted molecule because it lacks a transmembrane se- quence ...
7
Original Article Serum decoy receptor 3 is a diagnostic and prognostic biomarker in patients with colorectal cancer
... Background: Decoy receptor 3 (DcR3), a decoy receptor against Fas ligand belonging to the tumor necrosis factor receptor super-family, is over-expressed in types of ...
5
Decoy receptor 3: an endogenous immunomodulator in cancer growth and inflammatory reactions
... Decoy receptor 3 (DcR3), also known as tumor necrosis factor receptor (TNFR) superfamily member 6b (TNFRSF6B), is a soluble decoy receptor which can neutralize the biological functions ...
9
Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer
... Factor Receptor Superfamily member 10c (TNFRSF10c, also known as Decoy Receptor 1 (DCR1)) and Interleukin-1 Receptor-Associated Kinase 1 ...
15
β arrestin control of late endosomal sorting facilitates decoy receptor function and chemokine gradient formation
... its receptor, we transplanted cells expressing Cxcr7b-DsRed into embryos expressing ...the receptor appeared stable ...the decoy receptor appeared stable at the same time (supplementary ...
6
Rodent Herpesvirus Peru Encodes a Secreted Chemokine Decoy Receptor
... pUL21.5 decoy receptor that has exquisite specificity for human CCL5, binding with high affinity and effectively blocking chemokine receptor activation ...chemokine decoy receptors encoded by ...
9
A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia
... Figure 7 Decoy receptor 3 analogue (DcR3a) corrects the impairment in bacterial clearance associated with Fas ligand deficiency. Wild-type control mice (WT) and mice deficient in Fas ligand (gld) or Fas ...
8
The immunomodulator decoy receptor 3 improves locomotor functional recovery after spinal cord injury
... Decoy receptor 3 (DcR3/tumor necrosis factor recep- tor superfamily member (TNFRSF)-6B), a soluble recep- tor belonging to the tumor necrosis factor receptor superfamily, has been shown to be a ...
12
The combination of decoy receptor 3 and soluble triggering receptor expressed on myeloid cells-1 for the diagnosis of nosocomial bacterial meningitis
... apoptosis by neutralizing the activities of the following three members of the TNF superfamily: Fas ligand (FasL) [5], LIGHT [receptor homologous to lymphotoxins ex- hibits inducible expression, competes with ...
7
TRAIL Death Receptor 4, Decoy Receptor 1 and Decoy Receptor 2 Expression on CD8+ T Cells Correlate with the Disease Severity in Patients with Rheumatoid Arthritis
... The statistical package for the Social Sciences 13.0 soft- ware for Windows (SPSS Inc., Chicago, Ill) and Graph- Pad Prism version 5 (La Jolla, CA, USA) were used to plot the data and perform statistical analyses. In ...
9
Structural Determinants of Chemokine Binding by an Ectromelia Virus-Encoded Decoy Receptor
... The EVM1 protein encoded by Ectromelia virus is a member of a highly conserved family of poxvirus chemokine binding proteins that interfere with host immune surveillance processes. EVM1 is abundantly expressed early ...
11
A Decoy Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite
... In parallel with structural studies on these nAChR homologues, short- and long-chain 3FTxs from snake venom, such as α-bungarotoxin from Bungarus multicinctus (many- banded krait) (Huang et al., 2013), α-cobratoxin from ...
15
Dexamethasone stimulates expression of C type Natriuretic Peptide in chondrocytes
... signaling receptor Npr2 and up-reg- ulation of transcript levels for the decoy receptor Npr3 by DEX might counteract increased CNP levels to some degree; however, changes in the mRNA levels for the ...
7
Rational Design and Construction of a Knock-Out Vector for Targeting the Decoy Type 2 Interleukin -1 Receptor
... The expression of IL-1R2 is more confined, with neutrophils being the main source in mouse, unlike the ubiquitous IL-1R1 [7]. IL-1R2 is expressed in both membrane-bound (decoy receptor) and soluble form ...
9
Ziv-aflibercept in metastatic colorectal cancer
... a decoy receptor for vascular endothelial growth factor (VEGF)-A, VEGF-B, and placental growth factor (PlGF); it was approved in combination with 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) for the ...
13
Increased serum TRAIL and DR5 levels correlated with lung function and inflammation in stable COPD patients
... Abbreviations: BMI, body mass index; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; DR5, decoy receptor 5; FEV 1 , forced expiratory volume in 1 second; [r] ...
8
The effect of bisphosphonate treatment on osteoclast precursor cells in postmenopausal osteoporosis: The TRIO study
... the receptor RANK which is located on the osteoclast precursor cells as well as the mature osteoclast ...soluble decoy receptor, thus reducing the population of osteoclast precursor cells, the ...
18
Equipping Decoy Generation Algorithms for Template-free Protein Structure Prediction with Maps of the Protein Conformation Space
... by decoy generation algorithms relies on generating as many decoys as can be ...a decoy dataset. In this paper, we propose to equip a decoy generation algorithm with an evolving map of the protein ...
9
PR3 Email Honeypot
... The concept of honeypot has been successful in other domains to lure attackers and learn their techniques and behaviours. In this paper, the honeypot concept is applied to the email system in order to proactively detect ...
12