dengue virus serotypes 1–4
Simultaneous detection and differentiation of dengue virus serotypes 1 4, Japanese encephalitis virus, and West Nile virus by a combined reverse transcription loop mediated isothermal amplification assay
... Results: We developed a flexible reverse-transcription loop-mediated isothermal amplification (RT-LAMP) unit for the detection and differentiation of dengue virus serotypes 1-4 ...
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The prevalence of dengue virus serotypes in asymptomatic blood donors reveals the emergence of serotype 4 in Saudi Arabia
... from dengue-endemic countries [12, ...− 1, and the latter has also recently been isolated for the first time from symptomatic patients in Makkah city ...of dengue and its vector into other regions of ...
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Two dimensional VOPBA reveals laminin receptor (LAMR1) interaction with dengue virus serotypes 1, 2 and 3
... from 4 differ- ent dengue virus serotypes grown in C6/36 mosquito ...vidual dengue serotypes ...a dengue virus antigen or cocktail, 2 reactive spots were ...with ...
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Inhibition of Dengue Virus Serotypes 1 to 4 in Vero Cell Cultures with Morpholino Oligomers
... DEN virus titers in the presence of 5 to 20 M 3 ⬘ CS or 5 ⬘ SL P4-PMO were maximally inhibited to levels below the detection threshold of 80 to 160 PFU/ml in our growth curve ...P4-PMO-treated, ...
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Monkeys immunized with intertypic chimeric dengue viruses are protected against wild-type virus challenge.
... four dengue virus serotypes continue to pose a major public health problem in most tropical and subtropical ...against dengue is still not available. The current strategy for dengue ...
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The Dengue virus in Nepal: gaps in diagnosis and surveillance
... Dengue virus detection and epidemic pattern in Nepal Sparse information on DENV infection in Nepal was available prior to 2004 [17], which changed with the report of one Japanese foreigner being diagnosed ...
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Clade Replacements in Dengue Virus Serotypes 1 and 3 Are Associated with Changing Serotype Prevalence
... measures would affect clades of DENV-1 in such a different manner. We therefore considered whether the selection pres- sures imposed by different serotypes cocirculating in the pop- ulation, which will ...
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Circulating serotypes of dengue virus and their incursion into non endemic areas of Pakistan; a serious threat
... previous dengue outbreaks in Punjab, mortality and morbidity rate was highest in ...of dengue in the region, prevalence of all four serotypes (Table 1), mixed infection ...and 4) that ...
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Concurrent infections of dengue virus serotypes in Bali, Indonesia
... DENV serotypes involved in concurrent infec- tions were mostly involved DENV-1 and dominated by mix of DENV-1 and -2, followed by DENV-1 and -3, DENV-2 and -4, and DENV-3 and ...mild ...
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Dengue-specific serotype related to clinical severity during the 2012/2013 epidemic in centre of Brazil
... with dengue. The dengue virus (DENV) serotypes were identified in 243 ...in 4 (1.6%). Patients with the DENV-1 serotype were more prone to present with several clinical and ...
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A Tetravalent Dengue Vaccine Based on a Complex Adenovirus Vector Provides Significant Protection in Rhesus Monkeys against All Four Serotypes of Dengue Virus
... for dengue vi- ruses in macaques has been generally ...gue virus E peptides have not worked well in in vitro stimulations of primate peripheral blood mononuclear cells ...purified dengue-1 to ...
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Evolution and heterogeneity of multiple serotypes of Dengue virus in Pakistan, 2006–2011
... of 1 isolate (D2-PS51) that was closely related to a previous strain from Saudi Arabia, the remaining 25 isolates formed a distinct monophyletic clade with 78% bootstrap support (Figure ...
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Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India
... 2 dengue virus serotypes was reported from Puerto Rico in 1982 [30], since then different countries have reported the occur- rence of concurrent infections [21-26] in areas where mul- tiple ...
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Competitive advantage of a dengue 4 virus when co infecting the mosquito Aedes aegypti with a dengue 1 virus
... no dengue outbreaks were reported in the Americas while epidemics repeatedly struck countries in Southeast ...every 4–6 years [25] and the first cases of DHF being reported during the 1991–92 DENV-2 ...
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A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture
... file 1: Figure ...Table 1. These data reveal that MB21 could inhibit DENV-1, −2, −3 and −4 titers by 50, 82, 75 and 73%, ...(Figure 4, panels B-E) and corroborates NS1 as a marker for ...
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Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus.
... purified dengue-2 virus E ...from dengue-4 virus-immunized BALB/c mice did not recognize the dengue-4 virus E protein (42), whereas many of the CD8 1 clones ...
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Epidemiology of dengue hemorrhagic fever in Indonesia: analysis of five decades data from the National Disease Surveillance
... four dengue virus (DENV) serotypes (1–4), is the most important mosquito-borne viral disease in humans and is of major public health concern [1, ...as dengue fever (DF), ...
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Current perspectives on the spread of dengue in India
... Dengue virus belongs to the genus Flavivirus in the family ...(RNA) virus that is composed of three structural protein genes that encode the nucleocapsid or core protein, a mem- brane-associated ...
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Detection of dengue virus serotypes 1, 2 and 3 in selected regions of Kenya: 2011–2014
... presentations, dengue hemorrhagic fever (DHF) or dengue shock syndrome ...(DSS). Dengue viruses are mosquito-borne members of the Flavivirus genus, family Flaviviridae, first isolated in 1943 and ...
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Characterization and epitope mapping of Dengue virus type 1 specific monoclonal antibodies
... and dengue shock syndrome (DSS) ...other serotypes, case fatality rates might reach as high as 10–15% in hospitalized patients [2, 4, ...other serotypes are needed for the future improvement ...
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