Dentate granule cells
Reelin is a positional signal for the lamination of dentate granule cells
... of granule cell polarity and orientation The uniform bipolar morphology and parallel alignment of granule cells in the wild-type dentate gyrus is largely lost in reeler mutants, and in mutants ...
9
Borna Disease Virus Replication in Organotypic Hippocampal Slice Cultures from Rats Results in Selective Damage of Dentate Granule Cells
... the dentate gyrus (DG) of the hip- pocampal formation, where granule cells degenerate following BDV infection (5, 18, ...CA3 cells of the hippocampus receive major excitatory input via the ...
8
TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus
... these cells has never been ...positive cells were also present in the molecular layer and in the hilus (Figure ...for dentate granule cells together with their mossy fiber projections) ...
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Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice
... Using Nissl staining and immunohistochemistry for NeuN, the cytoarchitecture of the brains of SNAP-25 KI mice was examined for abnormalities. In Nissl-stained sections, few differences were detected between mutant and ...
17
COUP TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression
... Cajal-Retzius cells to the DG (Hodge et ...to dentate GCs from early stages to ...Cajal-Retzius cells, and the Cxcl12/Cxcr4 pathway, which represents the major chemotactic system involved in DG ...
14
Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus
... including granule cells in the dentate ...of dentate granule ...the dentate cell body layer as well as in astrocytes throughout the ...dissociated dentate neurons as well ...
12
The mechanisms for pattern completion and pattern separation in the hippocampus
... CA3 cells, which in acting as a pattern associator allow some pattern ...the dentate granule cells using competitive learning to convert grid-like entorhinal cortex firing to place-like ...of ...
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Adult neurogenesis modifies excitability of the dentate gyrus
... mature dentate granule cells based on both the shape and location of the ...Only cells with ≤25 M access resistance and ≥300 M input resistance were ...
16
NEUROPROTECTIVE ROLE OF BENINCASA HISPIDA LINN ON SENILE PLAQUE FORMATION IN COLCHICINE INDUCED EXPERIMENTAL RAT MODEL OF ALZHEIMER’S DISEASE
... of granule cell layers at CA3 region of the dentate gyrus of ...the dentate gyrus from the massive destruction of dentate granule cells and thereby prevented the senile plaque ...
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Visualizing Viral Dissemination in the Mouse Nervous System, Using a Green Fluorescent Protein-Expressing Borna Disease Virus Vector
... fected cells, we infected C57BL/6 mice intracranially with 10,000 FFU of ...identify dentate granule cells and cerebellar Purkinje neurons, respec- tively ...detected cells strongly ...
5
Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
... regulation of the kynurenine pathway has been reported in patients with psychiatric disorders. For example, in the neocortex of patients with schizophrenia and bipolar disorder, kynurenine and kynurenic acid levels are ...
14
P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus
... release and processing of proinflammatory cytokines including TNF-a [34,36,38]. Similar to previous studies [26-29], the present study shows that TNF-a immunor- eactivity is readily apparent in hippocampal neurons as ...
12
Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophy
... Slice cultures show an organotypic morphology [24]. In slice cultures of entorhinal cortex and hippocampus the entorhino-dentate fiber tract, i.e., perforant pathway is present (Fig. 1a, b) and terminates on ...
12
Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers
... independent dentate gyrus-CA3 circuits, which are hypothetically required to effectively encode information similar to, but distinct from, the preexisting circuits ...pyramidal cells promotes mossy fiber ...
9
Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury
... neuronal cells, which returned to basal levels 24 hours after the lesion and increased significantly thereafter due to expres- sion in astroglial ...glial cells of the whole degenerative area including the ...
13
The granule cell density of the dentate gyrus following administration of Urtica dioica extract to young diabetic rats
... Urtica dioica L. Stinging nettle has long been known worldwide as a medicinal plant. To study the benefits of the nettle in diabetic encephalopathy, the gran- ule cell density of the dentate gyrus of diabetic rats ...
9
Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression
... stem cells from their niche, which in vivo comprises a dense network of blood vessels, immune cells, neurotransmitters and chemical signals (reviewed by Gonçalves et ...
12
The role of support cells in the growth and differentiation of neurones in the abdominal ganglion of Aplysia
... Preventing metamorphosis and granule material release the ganglion remains embedded in granule-filled support cells by withholding the macroalgal substrate blocks half of the increase in[r] ...
16
Transit amplification in the amniote cerebellum evolved via a heterochronic shift in NeuroD1 expression
... of granule cell precursors with a distinct pial attachment (Hausmann and Sievers, 1985) forms a transient external germinal layer ...Purkinje cells are a prominent local source ...
5
Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus
... DG: dentate gyrus; EGL: external granule layer; FASD: fetal alcohol spectrum disorder; GCL: granule cell layer; GFAP: glial fibrillary acidic protein; HMGB1: high mobility group box 1; HPRT1: ...
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