dermal papilla
Sox2 positive dermal papilla cells specify hair follicle type in mammalian epidermis
... Fig. 2. Sox2 expression is restricted to guard/awl/auchene dermal papillae. (A) Bright-field images showing layers of medulla cells at the thickest point of the shaft of different hair types. (B) Percentage of ...
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In vitro Hair Growth Promoting Effects of Naringenin and Hesperetin on Human Dermal Papilla Cells and Keratinocytes
... human Dermal Papilla cells from hair follicle and keratinocytes (HaCaT cells) are yet to be ...human Dermal Papilla cells (DPCs) from hair follicle and keratinocytes ...
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Original Article Platelet-rich plasma promotes cell viability of human hair dermal papilla cells (HHDPCs) in vitro
... Abstract: Purpose: This study aimed to clarify the effect of platelet-rich plasma (PRP) on human hair dermal papilla cell (HHDPC) viability and expression levels of alkaline phosphatase (ALP) and versican. ...
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Hair growth promoting effect of Geranium sibiricum extract in human dermal papilla cells and C57BL/6 mice
... Results: GSE treatment proliferated and migrated human dermal papilla cells (hDPCs) more than treatment of 10 μ M minoxidil. GSE significantly stimulated the expression of Ki-67 protein and the mRNA levels ...
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Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth
... Figure 9. OSA-EVs and DP-EVs accelerate the telogen-to-anagen transition in C57BL/6 mice. (A) After hair depilation, mice dorsal skin was treated every 4 days with OSA-EVs, DP-EVs, PBS (negative control), or 3% minoxidil ...
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11β Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
... in DPCs plays an important role in modulating glucocorticoid action in DPCs. Pharmacological inhibition of 11β-HSD1 by a selective inhibitor significantly attenuated the glucocorticoid- induced inhibition of ...
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Dominant negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types
... The presence of dominant-negative SOX18 at E14.5 in primary DC cells had long-term consequences, despite the expression of SOX2 resulting in a loss of quiescent epidermal stem cells, extended anagen periods, poor ...
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Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells
... Background: Accumulating evidence indicates that reactive oxygen species (ROS) are an important etiological factor for the induction of dermal papilla cell senescence and hair loss, which is also known ...
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Identification of a new plant extract for androgenic alopecia treatment using a non radioactive human hair dermal papilla cell based assay
... used dermal papilla cells for either their cell-based or enzyme-based (source of 5 α -R) assay ...systems. Dermal papilla cells are a primary cell type that regulate hair growth, express 5α-R ...
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Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK 3β signaling pathway
... follicle dermal papilla (HDP) cells, a type of specialized fibroblast in the hair bulb, play an essential role in controlling hair growth and in conditions such as androgenic ...
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TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice
... A hair follicle (HF) is composed of several distinct epithe- lial and mesenchymal lineages (Schmidt-Ullrich and Paus 2005). Each stage of hair cycle is regulated by signaling between the epithelium and mesenchymal cells ...
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Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells
... Human dermal papilla; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAPK: Mitogen-activated protein kinase; miRNA: MicroRNA; PBS: Phosphate-buffered saline; PI: Propidium iodide; UTR: Untranslated region; ...
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Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline
... Although the hair shaft is derived from the progeny of keratinocyte stem cells in the follicular epithelium, the growth and differentiation of follicular keratinocytes is guided by a specialized mesenchymal population, ...
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Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
... DP: dermal papilla; DPCs: dermal papilla cells; DPC- Exos: dermal papilla cell derived exosomes; miRNA: micro RNA; P: passage; FACS: fluorescence-activated cell sorting; qRT-PCR: ...
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Induction of Cell Proliferation and Cell Death in Human Follicle Dermal Papilla Cells by Zinc Chloride
... follicle dermal papilla cells were ...follicle dermal papilla cells and the expression levels of cell cycle regulatory ...follicle dermal papilla ...follicle dermal ...
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Multimodal label-free imaging of living dermal equivalents including dermal papilla cells
... both dermal sheath (DS) and DP cells seeded into rat tail type I collagen contracted the collagen lattice to a similar degree, with both displaying significantly enhanced contractile ability over dermal ...
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Original Article Topical application of 8DSS induces anagen hair growth in telogenic mouse skin
... teins to the Frizzled (Fz) receptors leads to stabilization of cytoplasmic β-catenin, which enters the nucleus and interacts with the tran- scription factor T-cell factor/lymphoid enhancer factor (TCF/LEF) to regulate ...
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Original Article Epidermal growth factor promotes mesenchymal stem cell-mediated wound healing and hair follicle regeneration
... Many studies have focused on wound healing and hair regeneration [8-11]. The use of mes- enchymal stem cells (MSCs) is one of the most promising discoveries, which can contribute to wound closure acceleration, ...
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Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration
... MSCs in wound healing and cutaneous regeneration Cutaneous wound healing is a highly organized physio- logical process that restores the integrity of the skin following injury. It involves the interplay between vari- ous ...
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Use of human intra-tissue stem/progenitor cells and induced pluripotent stem cells for hair follicle regeneration
... or dermal HFSPCs were ...trichogenic dermal signals and/or potent hair inductive capacity of ...and dermal papilla cells, their precursor cells in the dermal sheath, or trichogenic ...
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