Detection HPV 16 E6/E7 mRNA transcripts in cervical tissue:
HPV genotype determination and E6/E7 mRNA detection for management of HPV positive women
... IS. HPV mRNA tests for the detection of cervical intraepithelial neoplasia: a systematic ...for cervical cancer screening working group the new Technologies for Cervical Cancer ...
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HPV OncoTect E6, E7 mrna Kit A highly specific molecular test for early detection of cervical cancer
... The HPV OncoTect ™ E6, E7 mRNA Kit is a unique detection method that measures both the number of transforming cells and the quantity of E6, E7 mRNA in each ...of ...
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Sensitivity and specificity of HR HPV E6/E7 mRNA test in detecting cervical squamous intraepithelial lesion and cervical cancer
... HR HPV E6/E7 mRNA, may significantly contribute to the earlier and more pre- cise detection of cervical neoplasia pathology in high-risk patients groups ...and cervical ...
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THE CARCINOGENIC POTENTIAL OF E6 & E7 GENES OF HIGH RISK HPV COMPARED WITH E6, E7 GENES OF LOW RISK HPV IN HUMAN CERVICAL CANCER: A REVIEW
... genital HPV infections and cervical cancer was first demonstrated in the early 1980s by Harold Zur Hausen, a German ...on Cervical Cancer, recognized HPV as an important cause of ...
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Labec Pharma, S.L HPV OncoTect : Flow cytometry assay based on E6/E7 mrna for the early diagnosis of cervical cancer.
... % HPV E6, E7 mRNA+ Cells The purpose of this study was to combine HPV DNA screening with HPV E6, E7 mRNA detection in an effort to improve the overall ...
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Aptima HPV E6/E7 mRNA Test Is as Sensitive as Hybrid Capture 2 Assay but More Specific at Detecting Cervical Precancer and Cancer
... the HPV tests was assessed on the basis of histological diagnosis, with CIN 2 ⫹ serving as the disease ...cross-sectional HPV data based on a single cervical brush specimen collected at the time of ...
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Type Specific Human Papillomavirus E6/E7 mRNA Detection by Real Time PCR Improves Identification of Cervical Neoplasia
... remaining HPV DNA was present, the DNase-treated samples were also run with the DNA detection protocol, ...step. mRNA detection was accepted only if the corresponding DNA was not detected or ...
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Presence of E6 and E7 mRNA from Human Papillomavirus Types 16, 18, 31, 33, and 45 in the Majority of Cervical Carcinomas
... different HPV type result by PCR versus NASBA: sequencing of the Gp5 ⫹ /Gp6 ⫹ consen- sus PCR product reported the presence of HPV-51, whereas type-specific PCR and NASBA gave positive results for ...
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Clinical Performance of the PreTect HPV Proofer E6/E7 mRNA Assay in Comparison with That of the Hybrid Capture 2 Test for Identification of Women at Risk of Cervical Cancer
... for detection of CIN 2 ⫹ in comparison with HC2, supplemented with HPV genotypic analysis using a standardized commercially available genotyping ...for E6/E7 mRNA and other molecular ...
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Prognostic and diagnostic validity of p16/Ki 67, HPV E6/E7 mRNA, and HPV DNA in women with ASCUS: a follow up study
... HPV E6/E7 mRNA test and p16/Ki-67 immunocyto- chemistry has been proposed as promising biomarkers for HPV oncogene ...that HPV E6/E7 mRNA test and p16/Ki-67 ...
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A novel HPV 16 L1 based chimeric virus like particle containing E6 and E7 seroreactive epitopes permits highly specific detection of antibodies in patients with CIN 1 and HPV 16 infection
... containing HPV-16 L1 protein fused with E6 and E7 seroreactive epitopes enable much better detection of IgG antibodies in the sera of CIN 1 patients positive for HPV-16 ...
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<p>An efficient method that combines the ThinPrep cytologic test with E6/E7 mRNA testing for cervical cancer screening</p>
... TCT, HPV DNA detection, and E6/E7 mRNA are widely applied for pri- mary ...DNA detection and E6/E7 testing is low, which causes a large number of overdiagnoses and ...
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High Risk Human Papillomavirus (hrHPV) E6/E7 mRNA Testing by PreTect HPV Proofer for Detection of Cervical High Grade Intraepithelial Neoplasia and Cancer among hrHPV DNA Positive Women with Normal Cytology
... a cervical smear in the greater Amsterdam area in The Netherlands from January 2005 till March ...population-based cervical screening program in which women between 30 and 60 years of age are invited for ...
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Original Article E6/E7 oncoproteins of high risk HPV-16 upregulate MT1-MMP, MMP-2 and MMP-9 and promote the migration of cervical cancer cells
... of cervical cancer cells. The overexpres- sion of HPV16 E6/E7 oncoproteins promoted MT1-MMP, MMP-2 and MMP-9 in cervical can- cer ...HPV16 E6/E7-positive cervi- cal cancer cell ...
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Expression of human papillomavirus type 16 E6 E7 open reading frame varies quantitatively in biopsy tissue from different grades of cervical intraepithelial neoplasia
... type 16 E6-E7 open reading frame are essential for transformation of the host ...Two mRNA species, E6*I and E6*II, generated by alternative splicing of a polycistronic ...
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The E7 Oncoprotein Is Translated from Spliced E6*I Transcripts in High-Risk Human Papillomavirus Type 16- or Type 18-Positive Cervical Cancer Cell Lines via Translation Reinitiation
... oncoprotein E7 is derived from spliced E6*I mRNAs in cervical cancer cells, as well as in cells trans- fected with corresponding expression ...the E6 coding region are responsible mainly for ...
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Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High Grade Lesions of the Cervix
... from HPV was detected more frequently than the E6 and E7 ...most HPV infections, only a few of which produce precancerous ...the detection of E6 and E7 mRNA in a ...
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Detection of HPV E7 transcription at single-cell resolution in epidermis
... 2014). mRNA sequencing of 31 cutaneous squamous cancers was unable to detect HPV transcripts even in samples that were HPV DNA positive (Arron et ...detected HPV transcripts in ...
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A study on HPV mRNA test and colposcopy in HIV positive women for early detection of cervical intraepithelial lesions
... HIV, HPV and ...of HPV infection in HIV positive women who were on ...of HPV and other lower genital tract infection in HIV positive women who are not on ART and also correlating colposcopic findings ...
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Overexpression of HPV E6/E7 Oncoproteins is a Marker of Progression to Cervical Cancer
... that E6 interaction with p53 can inhibit the binding of p53 to its site specific DNA sequences ...each E6 protein has for p53 thus 16E6 shows the highest level of site specific binding inhibition, 31E6 and ...
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