Dex, dexamethasone
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial
... tomography; Dex: Dexamethasone; EQ-5D: EuroQol Quality of Life questionnaire; GCP: Good Clinical Practice; GCS: Glasgow Coma Scale; HES: Hospital Episode Statistics; IDMEC: Independent Data Monitoring and ...
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Statistical analysis plan for the Dex CSDH trial: a randomised, double blind, placebo controlled trial of a 2 week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma
... Dex-CSDH is a multi-centre, clinical phase III, ran- domised, double-blind, placebo-controlled trial of dexam- ethasone for up to 2 weeks on clinical outcome following CSDH. In total, 750 symptomatic patients with ...
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Front line treatment of elderly multiple myeloma in the era of novel agents
... 1990s, dexamethasone was considered a simple, effective, and safe primary treatment for a large fraction of patients, mainly in North ...high-dose dexamethasone was recognized as a major source of concern ...
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Carfilzomib boosted combination therapy for relapsed multiple myeloma
... lenalidomide dexamethasone; CR, complete remission; Dara, daratumumab; dex, dexamethasone; DRd, daratumumab lenalidomide dexamethasone; ERd, elotuzumab lenalidomide dexamethasone; FDA, ...
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Induction regimens for transplant-eligible patients with newly diagnosed multiple myeloma: a network meta-analysis of randomized controlled trials
... plus dexamethasone; Dex, dexamethasone; HR, hazard ratio; OR, odds ratio; ORR, overall response rate; OS, overall survival; PAD, bortezomib plus doxorubicin plus dexamethasone; PFS, ...
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Reversal of corticosteroid insensitivity by p38 MAPK inhibition in peripheral blood mononuclear cells from COPD
... with dexamethasone or gW856553 alone or in combination for 1 hour and then stimulated with lPs (10 ng/ml) for 24 ...of dexamethasone, and (B) by dexamethasone in the presence of ...to ...
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A PROSPECTIVE COMPARATIVE STUDY OF SAFETY OF LENALIDOMIDE PLUS DEXAMETHASONE COMBINATION THERAPY VERSUS VAD (VINCRISTINE, DOXORUBICIN AND DEXAMETHASONE) REGIMEN IN THE TREATMENT OF MULTIPLE MYELOMA
... plus Dexamethasone (Len-Dex) and VAD (Vincristine, Doxorubicin and Dexamethasone) regimen are the two common drug therapies involved in the treatment of Multiple ...
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Intravitreal bevacizumab injections versus dexamethasone implant for treatment-naïve retinal vein occlusion related macular edema
... This study has several limitations. First, the patient selec- tion may be biased, as the decision of primary treatment modality was nonrandomized and performed by the treating clinician. On the other hand, baseline ...
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26S proteasome inhibitors inhibit dexamethasone dependent increase of tyrosine aminotransferase and tryptophan 2,3 dioxygenase mRNA levels in primary cultured rat hepatocytes
... inhibited Dex-dependent increase of TAT and TO mRNA levels in the nuclear faction at 7 h, at which time the in- crease reached ...by Dex in primary rat hepatocytes cultured for 2 h reached maximum at 2 h ...
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Post-marketing surveillance study of the safety of dexamethasone intravitreal implant in patients with retinal vein occlusion or noninfectious posterior segment uveitis
... The primary outcome measures were serious adverse events (SAEs) and adverse events of special interest (AESIs, determined based on important identified or potential risks of DEX listed in the Ozurdex EU Risk ...
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A Genetic Analysis of Glucocorticoid Receptor Signaling: Identification and Characterization of Ligand-Effect Modulators in Saccharomyces cerevisiae
... tion, DNA binding, and nuclear localization. The C Whereas most prior genetic studies of the glucocorti- terminus interacts with molecular chaperones, coactiva- coid receptor signaling pathway have analyzed candi- tors, ...
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The effect of alpha asarone, olive oil, and dexamethasone on collagen induced arthritis (CIA) in the mouse
... example, dexamethasone (DEX) repaired the articular surface and bone in zymosan-induced arthritis in the rat [15]; DEX significantly reduced the histology- cal severity of synovitis and bone damage ...
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In vitro evaluation of the synergistic antioxidant and anti inflammatory activities of the combined extracts from Malaysian Ganoderma lucidum and Egyptian Chlorella vulgaris
... Folin-Ciocalteau reagent, gallic acid (GA), ursolic acid (UA), rutin (RU), catechin, dextran sulfate (DS), 2,2 diphenyl-1-picrylhydrazyl (DPPH), Griess reagent, thio- barbituric acid (TBA), riboflavin, ...
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Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways
... drug dexamethasone (DEX) to stimulate the odontogenic differentiation of human dental pulp cells ...(HDPCs). DEX molecules were first loaded onto the BGN, and then the DEX-BGN complex was ...
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Self-assembled rosette nanotubes encapsulate and slowly release dexamethasone
... incorporate dexamethasone (DEX, an inflammatory and a bone growth promoting steroid) into RNTs was ...that DEX can be easily and quickly encapsulated into RNTs and released to promote osteoblast ...
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Development and Validation Method for Simultaneous Analysis of Retinoic Acid, Hydroquinone and Corticosteroid in Cream Formula by High-Performance Liquid Chromatography
... (HYQ), dexamethasone (DEX), triamcinolone acetonide (TSA), hydrocortisone acetate (HYA), betamethasone valerate (BEV) and retinoic acid (REA) in the cream dosage ...HYQ, DEX, TSA, HYA, BEV and REA ...
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Original Article A rare case of nasopharyngeal carcinoma in a patient with multiple myeloma after treatment by lenalidomide
... logic malignancies. Approximately 86,000 new cases of MM were reported annually worldwide [1]. Lenalidomide is an oral immunomodulatory drug (IMiD) approved in the United States for patients with MM. The introduction of ...
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High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis
... Abstract: Prolonged administration of an excessive dose of corticosteroids proved to be harmful for patients with acute lung injury (ALI). A previous study has found that repeated administration of an excessive dose of ...
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Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice
... c Isometric force as a function of stimulation frequency of TA muscle from mice implanted with osmotic pumps delivering saline or dexamethasone (Dex) and treated with REGN1033 or isotype[r] ...
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The efficacy and safety outcomes of the 0.19 mg fluocinolone acetonide implant after prior treatment with the 0.7 mg dexamethasone implant in patients with diabetic macular edema
... In March 2014, the first FAc implant was injected after CRT had again rebounded within 7 months of the fourth DEX implant being given (to 748 microns) and VA had started to worsen (50 letters). Figure 1 highlights ...
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