Diabetes insipidus
RENAL DIABETES INSIPIDUS
... one female infant (whose family history was not available) was considered to have mani fest renal diabetes insipidus.― The presence of decreased renal concentrating ability and mild cl[r] ...
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Lithium intoxication and nephrogenic diabetes insipidus: a case report and review of literature
... Abstract: Lithium is one of the drugs used widely in the treatment of mood disorders. However, it has a very narrow therapeutic index and side effects can be seen in many organ systems, one of which affects the kidneys. ...
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Metastatic Prostate Adenocarcinoma Presenting Central Diabetes Insipidus
... Diabetes insipidus is a disorder of a large volume of urine (diabetes) that is hypotonic, dilute, and tasteless ...of diabetes mellitus ...
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Rare occurrence of central diabetes insipidus with dermatomyositis in a young male
... Central diabetes insipidus (CDI), a rather disabling and severe disease characterized by polyuria and polydipsia, is caused by defects of the posterior pituitary, resulting in deficiency of the antidiuretic ...
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Methotrexate-associated lymphoproliferative disorder with hypopituitarism and central diabetes insipidus
... Patients treated with immunosuppressive drugs, especially methotrexate (MTX), rarely develop lymphoproliferative disorders (LPDs), known as MTX-related LPD (MTX–LPD). The primary site of MTX–LPD is often extranodal. This ...
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Metformin improves urine concentration in rodents with nephrogenic diabetes insipidus
... AQP2 and UT-A1 in vitro (12). In inner medullary suspensions from control animals, metformin increased AQP2 membrane association but did not increase UT-A1 in the membrane (12). These experiments suggested regulation of ...
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Lithium induced nephrogenic diabetes insipidus: in vivo and in vitro studies
... nephrogenic basis for the diabetes insipidus syndrome manifested by these three patients. The defect in water transport was further characterized in toad urinary bladders in vitro. Short-circuit current (I) ...
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DIABETES INSIPIDUS (DRUG TREATMENT AND ANIMAL MODELS): A REVIEW
... Depending on the severity of the condition, urine output can range from 2.6 quarts (about 2.5 liters) a day if you have mild diabetes insipidus to 16 quarts (about 15 liters) a day if the condition is ...
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Use of acetazolamide in lithium-induced nephrogenic diabetes insipidus: a case report
... Lithium-induced nephrogenic diabetes insipidus (Li-NDI) is a rare and difficult-to-treat condition. A study in mice and two recent papers describe the use of acetazolamide in Li-NDI in 7 patients (a case ...
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Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus
... nephrogenic diabetes insipidus (NDI) is the most prevalent renal side effect of chronic Li administration, with over 50% of patients developing hyposthenuria and 20%–40% of patients developing frank NDI ...
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Chlorpropamide action on renal concentrating mechanism in rats with hypothalamic diabetes insipidus
... To determine vasopressin (VP)-potentiating effect of chlorpropamide (CPMD), we studied the effect of CPMD in vivo and in vitro in kidneys and in specific tubule segments of rats with hypothalamic diabetes ...
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A micropuncture study of collecting tubule function in rats with hereditary diabetes insipidus
... hypothalamic diabetes insipidus. The tip of the left renal papilla was exposed and fluid was obtained by micropuncture from loops of Henle and from collecting ducts at the papillary tip, and at an average ...
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Combined central diabetes insipidus and cerebral salt wasting after craniotomy
... intracranial extension. Consent for surgery was not given until a year and a half later. By that time, a repeat MRI showed the tumour had extended into the left orbit and ethmoid sinus. A lateral rhinotomy, craniotomy ...
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Rare neonatal diabetes insipidus and associated late risks: Case report
... Case Presentation: A neonatal hemorrhagic stroke, caused by an aortic coarctation, caused right lower limb paresis, swallowing disability, and central diabetes insipidus in a term infant. The scant oral ...
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Congenital toxoplasmosis presenting as central diabetes insipidus in an infant: a case report
... CTox may affect the hypothalamic pituitary axis result- ing in variable deficiencies of the anterior as well as the posterior pituitary hormones. Isolated and selective defi- ciency of the antidiuretic hormone as in our ...
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Nephrogenic Diabetes Insipidus Due to Demethylchlortetracycline Hydrochloride in a Child
... RESPONSE TO EXOGENOUS ANTIDIURETIC HORMONE° with nephrogenic diabetes insipidus is usually unable to achieve a urine osmolality above 250 mOsm/kg, moderately severe volume depletion, as[r] ...
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Acquired nephrogenic diabetes insipidus in a dog with leptospirosis
... Leptospirosis is a zoonotic disease caused by infection with pathogenic Leptospira spp. [1]. Clinical signs associ- ated with leptospirosis can range from mild non-specific illness to severe disease associated with ...
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Key points in Diabetes Insipidus´ Diagnosis
... Diabetes insipidus is mainly characterized by polyuria, urinary volume over 3 L/day or 40mL/kg/day in adults, leading to subsequent polydipsia; these features are also present in most cases of ...
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THE USE OF CHLORPROPAMIDE IN DIABETES INSIPIDUS IN CHILDREN
... FIG. The effect of chlorpropamide on the oral glucose tolerance test in patients with diabetes insipidus. The “after therapy” glucose tolerance tests were performed in seven patients and[r] ...
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THE EFFECTS OF CHLOROTHIAZIDES IN NEPHROGENIC DIABETES INSIPIDUS
... The effect of “thiazide” therapy on linear growth of three children with nephrogenic diabetes insipidus... TABLE II[r] ...
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