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Diabetic Mice

In Vivo Antidiabetic Activity of Aqueous Extract of Psidium Quajava in Alloxanised Diabetic Mice

In Vivo Antidiabetic Activity of Aqueous Extract of Psidium Quajava in Alloxanised Diabetic Mice

... Introduction: Psidium quajava has for long been employed in the management of many diseases in Kenya, including diabetes mellitus. However, the use of this plant extract lacks scientific validation in regard to its ...

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Attenuation of diabetic hepatopathy in alloxan-induced diabetic mice by methanolic flower extract of Phlogacanthus thyrsiflorus Nees

Attenuation of diabetic hepatopathy in alloxan-induced diabetic mice by methanolic flower extract of Phlogacanthus thyrsiflorus Nees

... alloxan-induced diabetic mice. Diabetic mice prepared with alloxan (150 mg/kg) body weight (bw) were treated with effective different doses (150-550 mg/kg bw) of ...treated diabetic ...

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Anti-diabetic Activity of Diplocyclos palmatus Linn. in Streptozotocin-Induced Diabetic Mice

Anti-diabetic Activity of Diplocyclos palmatus Linn. in Streptozotocin-Induced Diabetic Mice

... promote conception . It has likewise been employed in more recent times in convulsions due to the presence of worms in the intestine, as a cathartic in dropsy, and in cases of chronic inflammations, attended with ...

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Effect of Gymnopetalum Cochinchinensis on Blood Glucose Level in Normal and Alloxan- Induced Diabetic Mice

Effect of Gymnopetalum Cochinchinensis on Blood Glucose Level in Normal and Alloxan- Induced Diabetic Mice

... alloxan-induced diabetic mice. In alloxan- induced diabetic mice, blood glucose was markedly reduced to 56% from that of control at 4 h, while in normal mice the blood glucose level was ...

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Pyrrolidine Dithiocarbamate Alleviated Anxiety in Diabetic Mice

Pyrrolidine Dithiocarbamate Alleviated Anxiety in Diabetic Mice

... technology. Mice were housed in groups of 4 animals per cage (30×19×13 cm) in a controlled environment with a 12 h light and 12 h dark cycle, average temperature of 22±2°, and 62±5% relative humidity with free ...

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Prevention of cataract in diabetic mice by topical pyruvate

Prevention of cataract in diabetic mice by topical pyruvate

... in diabetic mice was assessed by ophthalmoscopy after ...untreated diabetic group was significantly higher as compared with the pyruvate-treated ...

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In Vivo Anti-diabetic Effects of Aqueous Leaf Extracts of Rhoicissus tridentata in Alloxan Induced Diabetic Mice

In Vivo Anti-diabetic Effects of Aqueous Leaf Extracts of Rhoicissus tridentata in Alloxan Induced Diabetic Mice

... treated diabetic mice whose blood sugar levels was lowered by 58% within the first ...treated diabetic mice whose sugar levels was lowered by 70% within the same hour (Figure ...

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Immunization of AGE-modified albumin inhibits diabetic nephropathy progression in diabetic mice

Immunization of AGE-modified albumin inhibits diabetic nephropathy progression in diabetic mice

... the diabetic immunized groups showed more upregulated nephrin expression than the normal group, and the diabetic control groups showed the lowest nephrin intensity compared with the other ...

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Senescence associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors

Senescence associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors

... in mice that are simply Akita ...Akita diabetic mice is much less than in the double mutants, it is nevertheless more severe than that normally seen in most human insulin-dependent diabetics in ...

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Treadmill running improves hindlimb arteriolar endothelial function in type 1 diabetic mice as visualized by X-ray microangiography

Treadmill running improves hindlimb arteriolar endothelial function in type 1 diabetic mice as visualized by X-ray microangiography

... Our data in Fig. 3 demonstrated that there was no major vasodilation, thus no functional impairment was found in arteries of the diabetic mice compared to the control mice when 0.1 μg/kg/min of ...

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Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice

Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice

... diabetic mice. There was no dramatic morphologic difference between diabetic ASCs and healthy ASCs, nor did the expression of stem cell surface markers including CD29, CD105, and ...that ...

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ANTI DIABETIC EFFECTS OF ECLIPTA ALBA ON ALLOXAN INDUCED DIABETIC MICE

ANTI DIABETIC EFFECTS OF ECLIPTA ALBA ON ALLOXAN INDUCED DIABETIC MICE

... alba has been produce anabolic effects, enhancing the synthesis of certain modulator proteins in liver. On the other hand levels of urea, uric acid and creatinine increases in diabetic mice and these ...

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Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice

Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice

... We found that these compounds substantially elevated insulin secretion, which might subsequently attenuate dyslipidemia in CA or EA treated diabetic mice via improving lipid metabolism. Thus, the observed ...

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Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice

Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice

... in diabetic mice. We demonstrate that diabetic mice produced abnormally high skin levels of LTB 4 in response to MRSA skin infection and that these LTB 4 levels dictated uncontrolled ...

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Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice

Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice

... induced diabetic mice with model of hind-limb ischemia, were divided into non-diabetic control, diabetic control, and low- and high-dose rivaroxaban treatment groups, in order to evaluate the ...

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Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan induced diabetic mice

Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan induced diabetic mice

... albino mice bred in the animal house of Ethiopian Health and Nutrition Research Institute, Addis Ababa, Ethiopia, with weights ranging from 24 to 35 g and eight weeks of age were used for the experi- ...(5 ...

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Increased atherosclerosis in streptozotocin induced diabetic mice

Increased atherosclerosis in streptozotocin induced diabetic mice

... the diabetic effects of alloxan showed increased atherosclerosis in the aorta when fed a high fat diet, but characterization of lesions and atherogenic mechanisms was not ...Alloxan-induced diabetic rabbits ...

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EFFECT OF Tylophora indica ON DIABETE IN DIABETIC MICE

EFFECT OF Tylophora indica ON DIABETE IN DIABETIC MICE

... Hypoglycemic study: Results indicated that T. indica showed hypoglycemic activity (Table No.1). The hypoglycemic activity is first time reported in T. indica and this can be used as a substitute an anti-diabetic ...

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Inhibition of renin activity by aliskiren ameliorates diabetic nephropathy in type 1 diabetes mouse model

Inhibition of renin activity by aliskiren ameliorates diabetic nephropathy in type 1 diabetes mouse model

... of diabetic nephropathy. Male DBA/2J mice were induced to diabetes with streptozotocin, and the diabetic mice were treated for 16 weeks with saline or aliskiren, a renin en- zymatic ...in ...

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The promotion of nephropathy by Porphyromonas gingivalis lipopolysaccharide via toll-like receptors

The promotion of nephropathy by Porphyromonas gingivalis lipopolysaccharide via toll-like receptors

... the diabetic mice with Pg-LPS, a 100-µl volume (100 µg, 1 mg/ml) of Pg-LPS (3 mg/kg, LD50 = 30 mg/kg body weight, Wako) was administered repeatedly under the buccal mucosa once a week to the STZ-induced ...

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