diagnostic assays
Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection
... Unsafe medical practices, including unregulated blood transfu- sions without effective screening, as well as illicit injection drug use have historically been major drivers of viral hepatitis infec- tions. U.S. ...
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Variola Virus Specific Diagnostic Assays: Characterization, Sensitivity, and Specificity
... designed diagnostic assays (A4L and A36R) under- went extensive testing with a wide-ranging exclusivity panel to ensure that cross-reactivity with the pathogens most likely to be confused with smallpox did ...
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Diagnostic assays and sampling protocols for the detection of Batrachochytrium dendrobatidis
... ABSTRACT: Batrachochytrium dendrobatidis is a fun- gus belonging to the Phylum Chytridiomycota, Class Chytridiomycetes, Order Chytridiales, and is the highly infectious aetiological agent responsible for a poten- tially ...
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Comparison of Two Rapid Diagnostic Assays for Detection of Immunoglobulin M Antibodies to Dengue Virus
... commercial diagnostic assays, a dipstick enzyme-linked immunosorbent assay (ELISA) (Integrated Diagnostics, Baltimore, ...commercial assays provide sensitive and specific detection of anti-dengue ...
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Application of statistical process control to qualitative molecular diagnostic assays
... molecular assays are now processed in numbers sufficient to permit some form of SPC and this has been achieved for quantitative molecular assays (Liang et ...molecular diagnostic assays is ...
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Impact of Clinical Symptoms on Interpretation of Diagnostic Assays for Clostridium difficile Infections
... Asymptomatic Clostridium difficile colonization is common in hospitalized patients. Existing C. difficile assay comparisons lack data on severity of diarrhea or patient outcomes, limiting the ability to interpret their ...
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Isothermal diagnostic assays for the detection of soil transmitted helminths based on the SmartAmp2 method
... White precipitate in positive reactions can be detected by eye after brief centrifugation. This precipitate resulted from accumulation of the by-product, magnesium pyro- phosphate, whereas negative reactions remained ...
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Evaluation of three PCR based diagnostic assays for detecting mixed Plasmodium infection
... All PCR assays were completed on a BioRad iCycler (BioRad, Hercules, CA). Nested PCR was performed with primers and cycling conditions described by Snounou et al. [20] with modifications described in [27] in a 20 ...
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COMPARISON OF THREE RAPID DIAGNOSTIC ASSAYS FOR DIAGNOSIS OF LEPTOSPIROSIS IN A RESOURCE POOR SETTING
... laboratory diagnostic tests; culture, polymerase chain reaction, histopathological techniques or microscopic agglutination test [3] ...early diagnostic test [4] . Molecular diagnostic tools such as ...
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Survival analysis of diagnostic assays in Plasmodium falciparum malaria
... qPCR assays: human beta-2-microglobulin (B2MG) extraction con- trol, Plasmodium malariae/Plasmodium ovale species- specific duplex and ...qPCR assays were run using ABI 7900HT Real-time PCR System using the ...
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Companion diagnostics and molecular imaging-enhanced approaches for oncology clinical trials
... medicine, diagnostic approaches are helping pharmaceutical and biotechnology sponsors streamline the clinical trial ...Molecular assays and diagnostic imaging are routinely being used to stratify ...
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Heterotypic Humoral and Cellular Immune Responses following Norwalk Virus Infection
... modern diagnostic assays, such as the antibody VLP-HBGA blockade, large panels of GI and GII VLPs, the isolation of human monoclonal antibodies following infection, and a vari- ety of T-cell assays, ...
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Comparison of PCR based detection of Plasmodium falciparum infections based on single and multicopy genes
... rapid diagnostic assays based on the detection of parasite antigens in whole blood and DNA based methods for the detection of parasites, mainly the clinically important ...
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Immuno-Molecular Diagnosis of Toxoplasma gondii in Blood and Meat of Indigenous Chickens in Some Rural Regions of Iraq
... the diagnostic assays, significant differences in positive results were reported between indirect-ELISA and PCR technique among the tested samples of sera and meat as well as skeletal and cardiac ...
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Diagnostic Approach to Acute Diarrheal Illness in a Military Population on Training Exercises in Thailand, a Region of Campylobacter Hyperendemicity
... and diagnostic assay with 95% confidence ...various diagnostic tests derived from the same cases, an adjustment was made to account for correlations between areas ...and diagnostic assays were ...
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Profiles of Antibody Responses against Severe Acute Respiratory Syndrome Coronavirus Recombinant Proteins and Their Potential Use as Diagnostic Markers
... of diagnostic assays that can detect SARS-CoV ...as diagnostic antigens for serological assays, the viral proteins were expressed individually in mammalian and/or bacterial cells and tested ...
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Applied Epidemiology of Communicable Disease at a National Level
... There are a few limitations to consider when interpreting these data. The use of national notifications restrict the study population to people who have been tested and diagnosed with infectious syphilis and may ...
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Improved Serodiagnosis of Bovine Brucellosis by Novel Synthetic Oligosaccharide Antigens Representing the Capping M Epitope Elements of Brucella O Polysaccharide
... ing assays were performed on thawed ...conventional assays: CFT (n ⫽ 44), SAT (n ⫽ 24), cELISA (n ⫽ 58), or iELISA (n ⫽ ...four assays, 36 were positive in three, 16 were positive in two, and 8 were ...
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Reduction of Diagnostic Window by New Fourth Generation Human Immunodeficiency Virus Screening Assays
... The results obtained for the 17 seroconversion panels are summarized in Table 1. Ten of the 17 seroconversions were detected between 2 and 20 days earlier with fourth-generation assays than with the HIV-1/HIV-2 ...
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Diagnostic accuracy of contemporary and high-sensitivity cardiac troponin assays used in serial testing, versus single-sample testing as a comparator, to triage patients suspected of acute non-ST-segment elevation myocardial infarction: a systematic review protocol
... the diagnostic accuracy of contemporary and high-sensitivity cardiac troponin assays, when used in serial testing to identify MI in symptomatic patients presenting to the ...
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