diet-induced obese
Effect of vitamin A and E on carbohydrate and lipid metabolism in diet induced obese wistar rats
... changes induced in lipid profiles suggesting an improvement in insulin sensitivity through up-regulation in LPL STREBP-1a and STREBP-1c expression, while FAS expression was down ...in diet-induced ...
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Adipose tissue miRNA level variation through conjugated linoleic acid supplementation in diet-induced obese rats
... normal-fat diet (NFD) and high-fat diet (HFD) ...the diet-induced obese rats were randomly selected to receive 500 mg CLA per 1 kg body weight for 4 ...
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Supplementation of Syzygium cumini seed powder prevented obesity, glucose intolerance, hyperlipidemia and oxidative stress in high carbohydrate high fat diet induced obese rats
... zotocin induced diabetic rats ...tetrachloride induced rats ...glutamate induced obese rats ...fat diet fed rats [17, ...fat diet induced obese ...in diet ...
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Weight Management Effects of a Mixture of Conjugated Linoleic Acid and L-Carnitine in Diet Induced Obese Rats
... LC and CLA are in a close metabolic inter- relationship and few studies have clarified the similar or complementary role of them in fat metabolism [23]. For example, LC transports long-chain fatty acids across ...
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Diet induced obese mice develop peripheral, but not central, resistance to leptin
... fat diet for up to 56 d, providing a fairly rigorous evalu- ation of their leptin ...these diet-induced obese ...the diet-induced obese ...
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Germinated brown rice ameliorates obesity in high fat diet induced obese rats
... Previous studies of methanol extract [9] and water ex- tract [10] of GBR demonstrated suppression on body weight gains on mice fed on HFD. Ho et al. [9] reported that methanol extract of GBR was able to reduce adipo- ...
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Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats
... Since we found significantly lower fasting insulin lev- els in rats treated with sulodexide, this agent may affect the early stage of insulin resistance in high fat diet. Sulodexide is a blend of two ...
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Adipose-derived mesenchymal stem cells improve glucose homeostasis in high-fat diet-induced obese mice
... Methods: Seven-week-old C57BL/6 mice were fed a high-fat diet for 20 weeks to generate the DIO mouse model. Mice were given a single intravenous infusion of ex vivo expanded syngeneic ASCs at 2 × 10 6 cells per ...
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Effects of exercise and diet change on cognition function and synaptic plasticity in high fat diet induced obese rats
... fat diet affects synaptic plasticity to be reduced and learning as well as cognition of the brain with low levels of NGF and BDNF, but with regular exercise and dietary change, it has been identified to be ...
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Whole blueberry protects pancreatic beta-cells in diet-induced obese mouse
... blueberry-supplemented diet was ap- plied to the mice fed with the combination of high-fat diet (HFD) to examine the effect of whole blueberry on β-cell mass and insulin ...in diet (HFD + B) ...
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Effects of novel vaccines on weight loss in diet-induced-obese (DIO) mice
... Our approach in designing a therapeutic vaccine target- ing the counter-regulatory hormone somatostatin is based on the highly antigenic carrier protein chloramphenicol- acetyl transferase (CAT) which has been made ...
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Anti obesity effect of Yangkyuksanwha tang in high fat diet induced obese mice
... commercial diet (AIN-76A diet, Ral- ston Purina, ...normal diet group (C57bl/6 J-Nr), high-fat diet (HFD)-fed control group (HFD-CTL), HFD plus Gar- cinia cambogia extract 245 mg/kg positive ...
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Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet induced obese mice
... pathogenic features of excess adiposity and insulin re- sistance [3]. Dysregulation of hepatic lipid homeostasis is thought to be important in the development of fatty liver, such as reduced fatty acid oxidation, ...
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Anti obesity activity of Taraxacum officinale in high fat diet induced obese rats
... in obese subjects via inhibiting of gastric and pancreatic lipase, an enzyme that is crucial for the digestion of the long chain triglycerides, which at a three daily doses of 120mg reduces fat absorption by 30% ...
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Disruption of the hippocampal and hypothalamic blood–brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate
... To examine oxidative stress in this model, we measured levels of protein carbonyls, 3-nitrotyrosine (3-NT) and 4-hydroxynonenal (HNE) as previously described [36]. Protein carbonyls and 3-NT are measurements of protein ...
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Importance of leptin signaling and signal transducer and activator of transcription 3 activation in mediating the cardiac hypertrophy associated with obesity
... Interestingly, obese LepR S1138 exhibited a more pronounced in- crease in mean heart weights not only compared to lean or diet-induced obese WT mice, but also com- pared to LepR db/db mice (P ...
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Gut derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition
... against diet-induced neural leptin ...in diet-induced obese mice, including reduced body weight and adiposity, and a decreased hypothalamic level of SOCS3, an inhibitor of leptin ...
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... fat diet induced obese Wistar ...in obese female rats than obese male ...in obese female rats in the present study is in agreement with Mendonca HC et ...
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Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy
... CCDC47 upregulation in a DIO model of cardiomyopathy While the effect of diabetes on left ventricular hypertro- phy has been studied [2], less is known about alterations in the atrium [28]. Disruption in calcium ...
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Obesity does not promote tumorigenesis of localized patient- derived prostate cancer xenografts
... this obese phenotype with an efficient and reproducible PDX approach that has been optimized to maintain survival and proliferation of human prostate cancer ...
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